A T1WI-fMRI image tumor collaborative segmentation method based on 3D-Unet and graph theory segmentation

Abstract

A T1WI-fMRI image tumor collaborative segmentation method based on 3D-Unet and graph theory segmentation is provided, the method comprises the following steps: step 1, obtaining a T1WI and fMRI tumorsegmentation data set, and carrying out preprocessing; Step 2, generating a training sample; Step 3, training two independent 3D-Unet network; carrying out tumor and tumor sub-region segmentation onthe T1WI image and the fMRI image respectively, and helping high-quality voxel-level tumor and tumor sub-region / non-tumor masks and probability graphs to be generated through the strong description capability of the network; and step 4, carrying out fine segmentation based on a graph theory method, and simultaneously generating final tumor and tumor subregion segmentation results on the T1WI and fMRI images by using the two obtained probability mapping graphs and the coarse segmentation mask in a continuous graph segmentation model with label consistency constraint. According to the invention,automatic and accurate description of tumors and tumor subregions (including tumor necrosis, active tumors and tumor peripheral edema) is realized.

Description

technical field [0001] The present invention relates to the field of image processing, in particular to a tumor image segmentation method based on deep learning. Background technique [0002] Brain tumors are abnormal tissue growths that can lead to increased intracranial pressure and damage to the central nervous system, thereby threatening the patient's life. Reliable detection and segmentation of brain tumors from magnetic resonance images can aid in surgical planning and treatment assessment in medical diagnosis. Currently, most brain tumors are segmented manually by medical experts, which takes a long time and relies too much on the subjective experience of experts. Computer-aided tumor segmentation plays an increasingly important role in modern medical analysis. However, due to the large spatial and structural variability of brain tumors, and the overlap of the gray intensity range of tumors with that of healthy tissues, traditional machine learning methods are still...

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Problems solved by technology

[0003] In order to overcome the problem that the existing single-modal image-based tumor segmentation method is difficult to express all the information of the tumor and the existing deep learning network cannot accurately describe the tumor boundary, the present invention proposes a segmentation method based on 3D-Unet and graph theory. Tumor cooperative segmentation method for T1WI-fMRI images, realizing automatic and accurate description of tumors and tumor subregions (including tumor necrosis, active tumors, and peritumoral edema)

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