Medicine composite for treating beriberi, preparation and preparation method and application of composite

A composition and drug technology, applied in the direction of drug combination, drug delivery, medical formula, etc., can solve side effects and other problems, achieve the effect of small human side effects, excellent beriberi treatment effect, and good compatibility

Pending Publication Date: 2019-04-16
恩施香友生物科技有限公司
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Nowadays, the treatment of beriberi is mainly ointment, such as "Daknine", "Parisone" and so on. While these ointments contain antifungal components, some ointments also contain hormone components, which bring great harm to the human body after use. side effects

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Medicine composite for treating beriberi, preparation and preparation method and application of composite
  • Medicine composite for treating beriberi, preparation and preparation method and application of composite

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Embodiment 1 treats the pharmaceutical composition of beriberi and the preparation of spray preparation

[0043] (1) Wash and dry Coptis chinensis, Cortex Phellodendri, Boluohui, Fangfeng, Schisandra, Saponaria, Veratrum, Safflower, Nepeta, walnut green bark, Dan bark, Digu bark, Fenzi, Dafengzi and agarwood .

[0044] (2) Weigh 100 g of each of the Chinese herbal medicines in (1), use 500 mL of ethanol aqueous solution with an ethanol volume fraction of 80%, heat and reflux at 100° C. to extract three times, filter, and combine the filtrates.

[0045] (3) Concentrate the filtrate in (2) with a membrane concentrator and then purify it by ODS reverse phase silica gel column chromatography. Put 1kg of ODS reverse-phase silica gel into a glass column, add the extract into the column, elute with ethanol aqueous solution with a volume fraction of 10%, 30%, 50%, and 80%, and collect 30%, 50%, and 80% The eluate was eluted with ethanol aqueous solution, concentrated to a vis...

Embodiment 2

[0048] Embodiment 2 treats the preparation of the pharmaceutical composition of beriberi and spray preparation

[0049] (1) Wash and dry Coptis chinensis, Cortex Phellodendri, Boluohui, Fangfeng, Schisandra, Saponaria, Veratrum, Safflower, Nepeta, walnut green bark, Dan bark, Digu bark, Fenzi, Dafengzi and agarwood .

[0050] (2) Weigh 100g of each medicinal material in (1), Coptidis Rhizoma Cortex Phellodendri, Phellodendron Phellodendron, Boluohui, Fangfeng, Schisandra Fructus and Agarwood were respectively extracted with 500mL ethanol water solution with 70% ethanol volume fraction, heated and refluxed at 100°C for 3 times, filtered, and combined filtrate. Saponaria, veratrum, safflower, nepeta, walnut green bark, paeonol bark, Digu bark, and fennel, were extracted with 500mL ethanol water solution with a volume fraction of 80% ethanol, heated and refluxed at 100°C for 3 times, filtered, and combined filtrate.

[0051] (3) Concentrate the filtrate in (2) to a viscous sta...

Embodiment 3

[0054] Embodiment 3 treats the preparation of the pharmaceutical composition of beriberi and spray preparation

[0055] (1) Wash and dry Coptis chinensis, Cortex Phellodendri, Boluohui, Fangfeng, Schisandra, Saponaria, Veratrum, Safflower, Nepeta, walnut green bark, Dan bark, Digu bark, Fenzi, Dafengzi and agarwood .

[0056] (2) Weigh 100 g of each medicinal material in (1), Coptidis Rhizoma Cortex Phellodendri, Phellodendron Phellodendron, Bo Luohui, Fangfeng, Schisandra Fructus and Agarwood were respectively extracted with 500 mL of ethanol aqueous solution with a volume fraction of 90% ethanol, heated and refluxed at 100°C for 3 times, filtered, and combined filtrate. Saponaria, veratrum, safflower, Nepeta, walnut green bark, paeonol bark, Digu bark, and Fleur desiccus were extracted with 500mL ethanol water solution with a volume fraction of 70% ethanol, heated and refluxed at 100°C for 3 times, filtered, and combined filtrate.

[0057] (3) Concentrate the filtrate in ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a medicine composite for treating beriberi, a preparation and a preparation method and application of the composite. The medicine composite comprises rhizoma coptidis, cortex phellodendri, pink plumepoppy herbs, radix saposhnikoviae, Chinese magnoliavine fruits, Chinese honey locust, veratrum nigrum, flos carthami, herba schizonepetae, walnut green seedcase, cortex moutan,cortex lycii, rhizoma dioscoreae hypoglaucae, chaulmoogratree seeds and agilawood. The raw materials of the medicine composite are traditional Chinese medicinal materials, artificial addition components do not exist, and the composite does not contain hormones and has a little effect on the human body. All the components are good in compatibility and supplement one another, and the prepared medicine composite has an excellent beriberi treatment effect. Multiple kinds of preparations with the medicine composite are provided, the spraying preparation is more convenient to use, and the part withberiberi is directly sprayed with the spraying preparation.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition and preparation for treating beriberi, a preparation method and application thereof. Background technique [0002] Athlete's foot, also known as "tinea pedis" in medicine, commonly known as "Hong Kong's foot", is a symptom caused by fungal infection of the feet. The specific manifestations are itching, erythema, papules, peeling, or blisters between the toes or on the soles of the feet, which can erode and ooze in severe cases. [0003] Medically, beriberi is usually divided into three types: erosive, vesicular, and keratotic beriberi. [0004] 1. Erosive type: it is more likely to occur between the third and fourth, fourth and fifth toes. At the beginning, the toes are wet, impregnated and whitish or have small blisters. After drying and desquamation, peeling off the dander becomes a moist, flushed, erosive surface,...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/12A61K9/14A61K9/06A61P17/00A61P31/10
CPCA61K9/0014A61K9/06A61K9/12A61K9/14A61K36/185A61K36/238A61K36/286A61K36/483A61K36/52A61K36/538A61K36/57A61K36/65A61K36/66A61K36/71A61K36/718A61K36/756A61K36/79A61K36/815A61K36/835A61K36/8945A61K36/896A61K2236/333A61K2236/51A61K2236/55A61P17/00A61P31/10A61K2300/00
Inventor 田从魁朱梦阳孟嘉星刘瑞炯刘雨赵祖龙
Owner 恩施香友生物科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap