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Anesthetic nasal spray and preparation method thereof

A technique for nasal spray and injection, which is applied in the field of anesthesia nasal spray and its preparation, can solve the problems of poor sensitivity, poor compatibility and the like, and achieves the effects of easy acceptance, simple use method and simple preparation process

Inactive Publication Date: 2019-04-16
杜皓
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to overcome the deficiencies of the prior art, to meet the needs of reality, to provide a nasal spray for anesthesia and its preparation method, which can be used for adult outpatient minor surgery to overcome the pain of local anesthesia injection, and can fully relieve preoperative and intraoperative tension , poor cooperation, poor sensitivity

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: a kind of nasal spray for anesthesia.

[0035] In terms of components by weight, it comprises: 4ml of dexmedetomidine hydrochloride injection; 2ml of sufentanil citrate injection; and 9ml of normal saline.

[0036] In this embodiment, the concentration of the dexmedetomidine hydrochloride injection is 110 μg / 1ml. The concentration of the sufentanil citrate injection is 60 μg / 1ml, and the normal saline is 0.9% normal saline.

[0037] Implementation, 2: A nasal spray for anesthesia.

[0038] In terms of components by weight, it comprises: 3ml of dexmedetomidine hydrochloride injection; 0.5ml of sufentanil citrate injection; and 8ml of normal saline.

[0039] In this embodiment, the concentration of the dexmedetomidine hydrochloride injection is 90 μg / 1ml. The concentration of the sufentanil citrate injection is 40 μg / 1ml. The physiological saline is 0.9% physiological saline.

Embodiment 3

[0040] Embodiment 3: a kind of nasal spray for anesthesia.

[0041] In terms of components by weight, it comprises: 4ml of dexmedetomidine hydrochloride injection; 1ml of sufentanil citrate injection; and 9ml of normal saline.

[0042] In this embodiment, the concentration of the dexmedetomidine hydrochloride injection is 100 μg / 1ml. The concentration of the sufentanil citrate injection is 50 μg / 1ml. The physiological saline is 0.9% physiological saline.

Embodiment 4

[0043] Embodiment 4: a kind of nasal spray for anesthesia.

[0044] In terms of components by weight, it comprises: 5ml of dexmedetomidine hydrochloride injection; 1.5ml of sufentanil citrate injection; and 10ml of normal saline.

[0045] In this embodiment, the concentration of the dexmedetomidine hydrochloride injection is 90 μg / 1ml. The concentration of the sufentanil citrate injection is 60 μg / 1ml. The physiological saline is 0.9% physiological saline.

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Abstract

The invention discloses an anesthetic nasal spray and a preparation method thereof. The anesthetic nasal spray can be used for overcoming local anesthesia injection pain in a minor operation of an adult outpatient clinic, can fully solve the problems of preoperative and intraoperative tension, poor compliance and poor sensitivity; the anesthetic nasal spray is prepared from, by weight, 3-5 ml of adexmedetomidine hydrochloride injection, 0.5-2 ml of a sufentanil citrate injection and 8-10 ml of normal saline. The preparation method of the anesthetic nasal spray comprises the following steps that a, the dexmedetomidine hydrochloride injection is sucked by a medical syringe A; b, the sufentanil citrate injection is sucked by a medical syringe B; c, the normal saline is sucked by the medicalsyringe B to dilute the sufentanil citrate injection; d, the liquids in the medical syringe A and medical syringe B are mixed, and then standing is performed for 3-10 minutes.

Description

technical field [0001] The invention relates to an anesthetic drug, in particular to a nasal spray for anesthesia and a preparation method thereof. Background technique [0002] At present, local injections of local anesthetics are basically used in adult outpatient minor operations. Patients are nervous before and during the operation, and local anesthetic injections are painful during the operation. It is very easy to cause excessive bleeding due to tension and pain, poor cooperation, poor sensitivity, and postoperative emotional depression. . Local anesthesia and general anesthesia for minor surgery have narrow indications, and patients cannot leave the hospital immediately after surgery, and are prone to nausea and vomiting. If simply giving dexmedetomidine hydrochloride nasal spray for adult outpatient minor surgery, there will be no analgesia, weak sedative effect, and it is difficult to achieve patient satisfaction. If you simply give sufentanil citrate injection in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/12A61K31/4535A61K31/4174A61P23/02
CPCA61K9/0043A61K9/12A61K31/4174A61K31/4535A61P23/02A61K2300/00
Inventor 杜皓
Owner 杜皓
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