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Manufacture method of micro-organism-inhibiting gel

A production method and gel technology, which can be applied to medical preparations with non-active ingredients, medical preparations containing active ingredients, antibacterial drugs, etc., and can solve problems such as inconvenience in life and work, and long-term cure

Inactive Publication Date: 2019-04-12
拍合尔尼萨吐尔孙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] During women's menstrual period, pain often makes women feel very distressed. Various gynecological diseases such as genital itching, waist and abdomen pain, abnormal leucorrhea, frequent urination, dysuria, etc. also often trouble women. , Work brings great inconvenience

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] A kind of preparation method of antibacterial gel, specifically comprises the following steps:

[0016] 1) Weigh raw materials, net selection for later use: Weigh 200g of Sophora flavescens, 150g of Cortex Phellodendri, 100g of Fructus Cnidii, 100g of Safflower, 50g of Peppermint, 0.3g of polyhexamethylene biguanide hydrochloride, 10ml of glycerin, 15g of triethanolamine, Parkin methyl ester 3g, ethanol 230ml, carbomer 20g, drinking water 8400g, purified water 1000g;

[0017] 2) Dissolve 3 g of methylparaben in 20 ml of ethanol to make a methylparaben solution for subsequent use;

[0018] 3) Take Sophora flavescens, Phellodendron cortex, Cnidium chinensis, safflower, mint and add water to decoct twice: add 4800g of drinking water for the first time, decoct for 1.5 hours; add 3600g of drinking water for the second time, decoct for 1 hour, filter and combine Concentrate the filtrate twice into an extract with a relative density of 1.10 to 1.20 at 60°C, add ethanol to the...

Embodiment 2

[0023] 1) Weigh raw materials, net selection for later use: Weigh 220g of Sophora flavescens, 140g of Cortex Phellodendri, 90g of Fructus Cnidii, 110g of Safflower, 40g of Peppermint, 0.3g of polyhexamethylene biguanide hydrochloride, 10ml of glycerin, 15g of triethanolamine, Parkin methyl ester 3g, ethanol 230ml, carbomer 20g, drinking water 8400g, purified water 1000g;

[0024] 2) Dissolve 3 g of methylparaben in 20 ml of ethanol to make a methylparaben solution for subsequent use;

[0025] 3) Take Sophora flavescens, Phellodendron cortex, Cnidium chinensis, safflower, mint and add water to decoct twice: add 4800g of drinking water for the first time, decoct for 1.5 hours; add 3600g of drinking water for the second time, decoct for 1 hour, filter and combine Concentrate the filtrate twice into an extract with a relative density of 1.10 to 1.20 at 60°C, add ethanol to the extract to make the alcohol content reach 75%, stir and mix for alcohol precipitation, let stand for 24 h...

Embodiment 3

[0030] 1) Weigh raw materials, net selection for later use: Weigh 180g of Sophora flavescens, 160g of Cortex Phellodendri, 110g of Fructus Cnidii, 90g of Safflower, 60g of Peppermint, 0.3g of polyhexamethylene biguanide hydrochloride, 10ml of glycerin, 15g of triethanolamine, Parkin methyl ester 3g, ethanol 230ml, carbomer 20g, drinking water 8400g, purified water 1000g;

[0031] 2) Dissolve 3 g of methylparaben in 20 ml of ethanol to make a methylparaben solution for subsequent use;

[0032] 3) Take Sophora flavescens, Phellodendron cortex, Cnidium chinensis, safflower, mint and add water to decoct twice: add 4800g of drinking water for the first time, decoct for 1.5 hours; add 3600g of drinking water for the second time, decoct for 1 hour, filter and combine Concentrate the filtrate twice into an extract with a relative density of 1.10 to 1.20 at 60°C, add ethanol to the extract to make the alcohol content reach 75%, stir and mix for alcohol precipitation, let stand for 24 h...

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PUM

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Abstract

The present invention relates to a manufacture method of micro-organism-inhibiting gel. The manufacture method comprises the following steps: 1) raw materials are weighed and the weighed raw materialsare cleaned and selected for a standby application; 2) 20 ml of ethanol is taken to dissolve 3 g of methyl 4-hydroxybenzoate to prepare a methyl 4-hydroxybenzoate solution for a standby application;3) radix sophorae flavescentis, cortex phellodendri, fructus cnidii, safflowers and mint are taken, water is added, and the materials are cooked twice to obtain an extractum for a standby application;4) 20 g of carbomer is taken, 100 g of purified water is added, and the carbomer is soaked for 24 hours until fully swollen to obtain a gel matrix for a standby application; 5) the methyl 4-hydroxybenzoate solution is mixed with the extractum, polyhexamethylene biguanide hydrochloride and glycerin are added, triethanolamine is added dropwise to adjust pH to 7, purified water is supplemented to atotal mass of 1,000 g, and stirring and mixing evenly are conducted for a standby application; and 6) sub-packaging, inspecting, packaging, and storing after qualified are conducted. Advantages are asfollows: the micro-organism-inhibiting gel with an average micro-organism-inhibiting rate of 50% or more against staphylococcus aureus, candida albicans and escherichia coli can be prepared, and themicro-organism-inhibiting gel has remarkable results in diseases of genital itching, waist and abdomen pains, abnormal leukorrhea, frequent urination, odynuria, etc.

Description

technical field [0001] The invention relates to a preparation method of antibacterial gel. Background technique [0002] During women's menstrual period, pain often makes women feel very distressed. Various gynecological diseases such as genital itching, waist and abdomen pain, abnormal leucorrhea, frequent urination, dysuria, etc. also often trouble women. , Work brings great inconvenience. Contents of the invention [0003] The object of the present invention is to provide a method for making antibacterial gel to solve the problems raised in the above-mentioned background technology. [0004] In order to solve the above-mentioned technical problems, the technical solution provided by the invention is: a method for making an antibacterial gel, specifically comprising the following steps: [0005] 1) Weigh raw materials, net selection for later use: Weigh 180-220g of Sophora flavescens, 140-160g of Cortex Phellodendri, 90-110g of Cnidium Fructus, 90-110g of Safflower, 40...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K47/32A61K36/756A61P15/02A61P31/04A61K31/785
CPCA61K9/0034A61K9/06A61K31/785A61K36/234A61K36/286A61K36/489A61K36/534A61K36/756A61K47/32A61P15/02A61P31/04A61K2300/00Y02A50/30
Inventor 拍合尔尼萨·吐尔孙
Owner 拍合尔尼萨吐尔孙
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