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Whitening composition and preparation method thereof

A composition and whitening technology, applied in the direction of pharmaceutical formulations, cosmetic preparations, dressing preparations, etc., can solve the problems of inducing other diseases, skin allergies, pigmentation, etc., and achieve low production equipment requirements and simple and convenient steps Effect

Inactive Publication Date: 2019-04-02
深圳市琉璃光生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the whitening and freckle-removing products currently on the market add some traditional Chinese medicine extracts, minerals (pearl powder), vitamin C and its derivatives, glycolic acid, arbutin, ethanol, etc., but after long-term use by consumers, the skin will have allergic reactions 1. The effect of whitening and removing freckles is not good, and some may cause pigmentation, making the spots grow longer and more, and even more serious and even induce other diseases

Method used

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  • Whitening composition and preparation method thereof
  • Whitening composition and preparation method thereof
  • Whitening composition and preparation method thereof

Examples

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preparation example Construction

[0050] The preparation method of whitening composition comprises:

[0051] Pre-formulation step: Dissolve nicotinamide, glycerin, betaine and allantoin in water to obtain phase A;

[0052] Mix propylene glycol, sodium hyaluronate and hydroxyethyl cellulose to obtain phase B;

[0053] Mix tranexamic acid and citric acid to obtain phase C;

[0054] Dissolve polypeptide, water-soluble vitamin E, hydroxyethylurea, PEG / PPG-17 / 6 copolymer and preservative in water to obtain phase D;

[0055] Mix PEG-40 hydrogenated castor oil with essence to obtain Phase E;

[0056] Mixing step: heat phase A and phase B to 80-90°C and adjust the stirring speed to 50-80rpm, then homogenize for 3-8min at a homogenizing speed of 1500-3000rpm; keep the stirring speed at 50-80rpm and keep warm for 30- After cooling down to 50°C, adjust the stirring speed to 40-60rpm and stir for 10-20min, add phase C and stir for 20-50min; after cooling down to 38°C, adjust the stirring speed to 30-50rpm and stir for ...

Embodiment 1-3

[0059] The whitening composition component of embodiment 1-3 is as shown in table 2:

[0060] Table 2 Example 1-3 Whitening Composition Components and Consumption by Weight

[0061]

[0062]

Embodiment 1

[0065] In embodiment 1, concrete mixing step is:

[0066] Heat phase A and phase B to 80-90°C and adjust the stirring speed to 60rpm, then homogenize for 3min at a homogenizing speed of 1500rpm; keep the stirring speed at 60rpm and keep it warm for 30min; after cooling down to 50°C, adjust the stirring speed to 40rpm Stir for 10 minutes, add phase C and stir for 30 minutes; after cooling down to 38°C, adjust the stirring speed to 30 rpm and stir for 10 minutes, then add carnosine, phase E and phase D and stir for 30 minutes to obtain a whitening composition.

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Abstract

The invention discloses a whitening composition and a preparation method thereof. The whitening composition comprises the following components in parts by weight: 0.5-5 parts of nicotinamide, 0.5-5 parts of tranexamic acid, 0.1-5 parts of polypeptide, 0.2-2 parts of water-soluble vitamin E and 0.1-2 parts of carnosine. The preparation method of the whitening composition comprises the following steps of performing pre-blending to obtain an A phase, a B phase, a C phase, a D phase and an E phase; and performing mixing: heating the A phase and the B phase, performing stirring, performing homogenizing, reducing the temperature to 50 DEG C, adding the C phase, reducing the temperature to 38 DEG C, and sequentially adding the carnosine, the E phase and the D phase so as to obtain the whitening composition. The whitening composition has safety and tenderness, and can generate favorable skin feel after being applied.

Description

technical field [0001] The invention relates to a whitening composition and a preparation method thereof, belonging to the technical field of preparation of skin care products. Background technique [0002] The color of human skin mainly depends on the content and distribution of melanin, and the structure, function and quantity of melanocytes directly affect the content of melanin in the skin and are the decisive factors for the production of melanin. There must be three substances involved in the synthesis of melanin: ① Tyrosine is the main raw material for producing melanin; ② Tyrosinase is the main rate-limiting enzyme for converting tyrosine into melanin; ③ Tyrosine is produced under the action of tyrosinase Melanin is produced, and this action is an oxidation process, which must be combined with oxygen to be converted into melanin. With the deepening of molecular biology research, the whitening regulation mechanism and biological information pathway have become more a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/67A61K8/44A61K8/64A61Q19/02
CPCA61K8/675A61K8/44A61K8/64A61K8/678A61K2800/592A61K2800/782A61Q19/02
Inventor 曾芳芳尹启倩王泽智刘磊蒋旭文
Owner 深圳市琉璃光生物科技有限公司
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