Bamboo leaf and radix bupleuri wall-broken decoction piece for treating cold, mumps and tonsillitis and preparation method thereof
A technology of bamboo-leaf Bupleurum and tonsillitis, which is applied in the field of broken-wall decoction pieces of bamboo-leaf Bupleurum and its preparation, which can solve the problems of no industry norms and not widely used, and achieve the effect of good product composition consistency and stable quality
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[0016] The preparation method of the broken wall decoction pieces of Bupleurum bupleurum of the present invention comprises the following steps:
[0017] (a) Pre-crushing the dried Bupleurum bupleuri medicinal material into particles with a particle size of 10-100 mesh, and then soaking in an aqueous ethanol solution, wherein the aqueous ethanol solution has a concentration of 30-60% by weight;
[0018] (b) filtering, and freeze-drying the obtained filter cake, the freeze-drying conditions include: the temperature is -10°C to -50°C, and the vacuum degree is 5-50Pa;
[0019] (c) placed at a temperature of -10°C to 0°C for 1-3 hours;
[0020] (e) placing the obtained bupleurum bupleuri granules under vacuum conditions for microwave treatment, followed by ultrafine pulverization to obtain ultrafine powders with a particle size below 40 microns;
[0021] (f) mixing the ultrafine powder with an aqueous ethanol solution, and then performing granulation and drying, wherein the conce...
Embodiment 1
[0036] (1) Get 2.0kg of bamboo leaf Bupleurum medicinal material, pre-crushed to a particle size of 50 mesh particles, then add 4 times the volume of bamboo leaf Bupleurum granules in 45% by weight ethanol solution, soak for 2 hours at 70 ° C, and use 200 mesh Filter with a stainless steel wire mesh, and freeze-dry the obtained filter cake at -20° C. under a vacuum of 30 Pa. After the bamboo leaf Bupleurum granules were dried, they were placed at -5°C for 2 hours.
[0037] (2) Place the Bupleurum bupleuri particles obtained in step (1) under vacuum conditions for microwave treatment. The microwave treatment conditions are as follows: the temperature is 25°C, the time is 30min, the microwave power is 15kW, and the vacuum degree is 15Pa.
[0038] (3) Using a CW5-100QA wall-breaking ultrafine pulverizer to ultrafinely pulverize the Bupleurum bupleuri particles obtained in step (2), to obtain ultrafine powder with a particle size of 5-30 microns.
[0039] (4) Mix the ultrafine po...
Embodiment 2
[0041] (1) Get 2.0kg of bamboo leaf Bupleurum medicinal material, pre-crushed to a particle size of 80 mesh particles, then add 60% by weight ethanol solution of 3 times the volume of bamboo leaf Bupleurum granules, soak for 3 hours at 50 ° C, and use 200 mesh Filter with a stainless steel wire mesh, and freeze-dry the obtained filter cake at -30° C. under a vacuum of 20 Pa. After the bamboo leaf Bupleurum granules were dried, they were placed at -8°C for 1 hour.
[0042] (2) Put the Bupleurum bupleuri granules obtained in step (1) under vacuum conditions for microwave treatment. The microwave treatment conditions are as follows: the temperature is 20°C, the time is 40min, the microwave power is 10kW, and the vacuum degree is 10Pa.
[0043] (3) Using a CW5-100QA wall-breaking ultrafine pulverizer to ultrafinely pulverize the Bupleurum bupleuri particles obtained in step (2), to obtain ultrafine powder with a particle size of 5-30 microns.
[0044] (4) Mix the ultrafine powder w...
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