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Bamboo leaf and radix bupleuri wall-broken decoction piece for treating cold, mumps and tonsillitis and preparation method thereof

A technology of bamboo-leaf Bupleurum and tonsillitis, which is applied in the field of broken-wall decoction pieces of bamboo-leaf Bupleurum and its preparation, which can solve the problems of no industry norms and not widely used, and achieve the effect of good product composition consistency and stable quality

Inactive Publication Date: 2019-03-29
JIANGXI GROUNDIONG PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the broken-wall decoction piece technology is not widely used in domestic decoction piece production enterprises, and no real industry norms have been formed.
Therefore, research and development of a preparation method of broken Chinese medicine decoction pieces, give full play to the advantages of using the whole ingredients of Chinese medicine broken wall decoction pieces, retain all the medicinal ingredients of traditional Chinese medicine by breaking the wall, which is more conducive to the absorption of medicinal ingredients by users , in order to alleviate the problem that the existing traditional Chinese medicine granules can only extract part of the medicinal ingredients after adding water to concentrate, it becomes very necessary and urgent
However, there is no report about the broken wall decoction pieces of Bupleurum bupleuri and its preparation process

Method used

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Examples

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Effect test

preparation example Construction

[0016] The preparation method of the broken wall decoction pieces of Bupleurum bupleurum of the present invention comprises the following steps:

[0017] (a) Pre-crushing the dried Bupleurum bupleuri medicinal material into particles with a particle size of 10-100 mesh, and then soaking in an aqueous ethanol solution, wherein the aqueous ethanol solution has a concentration of 30-60% by weight;

[0018] (b) filtering, and freeze-drying the obtained filter cake, the freeze-drying conditions include: the temperature is -10°C to -50°C, and the vacuum degree is 5-50Pa;

[0019] (c) placed at a temperature of -10°C to 0°C for 1-3 hours;

[0020] (e) placing the obtained bupleurum bupleuri granules under vacuum conditions for microwave treatment, followed by ultrafine pulverization to obtain ultrafine powders with a particle size below 40 microns;

[0021] (f) mixing the ultrafine powder with an aqueous ethanol solution, and then performing granulation and drying, wherein the conce...

Embodiment 1

[0036] (1) Get 2.0kg of bamboo leaf Bupleurum medicinal material, pre-crushed to a particle size of 50 mesh particles, then add 4 times the volume of bamboo leaf Bupleurum granules in 45% by weight ethanol solution, soak for 2 hours at 70 ° C, and use 200 mesh Filter with a stainless steel wire mesh, and freeze-dry the obtained filter cake at -20° C. under a vacuum of 30 Pa. After the bamboo leaf Bupleurum granules were dried, they were placed at -5°C for 2 hours.

[0037] (2) Place the Bupleurum bupleuri particles obtained in step (1) under vacuum conditions for microwave treatment. The microwave treatment conditions are as follows: the temperature is 25°C, the time is 30min, the microwave power is 15kW, and the vacuum degree is 15Pa.

[0038] (3) Using a CW5-100QA wall-breaking ultrafine pulverizer to ultrafinely pulverize the Bupleurum bupleuri particles obtained in step (2), to obtain ultrafine powder with a particle size of 5-30 microns.

[0039] (4) Mix the ultrafine po...

Embodiment 2

[0041] (1) Get 2.0kg of bamboo leaf Bupleurum medicinal material, pre-crushed to a particle size of 80 mesh particles, then add 60% by weight ethanol solution of 3 times the volume of bamboo leaf Bupleurum granules, soak for 3 hours at 50 ° C, and use 200 mesh Filter with a stainless steel wire mesh, and freeze-dry the obtained filter cake at -30° C. under a vacuum of 20 Pa. After the bamboo leaf Bupleurum granules were dried, they were placed at -8°C for 1 hour.

[0042] (2) Put the Bupleurum bupleuri granules obtained in step (1) under vacuum conditions for microwave treatment. The microwave treatment conditions are as follows: the temperature is 20°C, the time is 40min, the microwave power is 10kW, and the vacuum degree is 10Pa.

[0043] (3) Using a CW5-100QA wall-breaking ultrafine pulverizer to ultrafinely pulverize the Bupleurum bupleuri particles obtained in step (2), to obtain ultrafine powder with a particle size of 5-30 microns.

[0044] (4) Mix the ultrafine powder w...

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Abstract

The present invention relates to the technical field of traditional Chinese medicine wall-broken decoction pieces and discloses a bamboo leaf and radix bupleuri wall-broken decoction piece for treating cold, mumps and tonsillitis and a preparation method thereof. The method comprises the following steps: (a) dried bamboo leaves and radix bupleuri are pre-crushed into particles having a particle size of 10-100 meshes, and then the pre-crushed particles are soaked using an ethanol aqueous solution; (b) filtering is conducted: an obtained filter cake is freeze-dried; (c) placing is conducted at atemperature of -10 DEG C-0 DEG C for 1-3 hours; (e) the obtained bamboo leaf and radix bupleuri particles are subjected to a microwave treatment under vacuum conditions and then ultrafine crushing isconducted; and (f) the obtained ultrafinely crushed fine powder is mixed with the ethanol aqueous solution, and then granulating and drying are conducted. The used method can prepare the bamboo leafand radix bupleuri wall-broken decoction piece with a relatively high wall breaking ratio.

Description

technical field [0001] The invention relates to the technical field of broken-wall decoction pieces of traditional Chinese medicine, in particular to a broken-wall decoction piece of Bupleurum bupleurum from bamboo leaves for treating colds, mumps and tonsillitis and a preparation method thereof. Background technique [0002] Broken-wall decoction pieces of traditional Chinese medicine is a traditional Chinese medicine decoction piece processed in powder form by using modern ultrafine pulverization technology. Broken wall decoction pieces of traditional Chinese medicine are all ingredients used as medicine, and the medicinal material basis remains unchanged, which is in line with the connotation of Chinese medicine decoction pieces. It can be directly brewed and taken together with the dregs of the medicine. However, the broken-wall decoction pieces technology is not widely used in domestic decoction pieces production enterprises, and no real industry norms have been formed...

Claims

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Application Information

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IPC IPC(8): A61K36/233A61P11/00A61P11/04A61P31/14
CPCA61K36/233A61K2236/10A61K2236/15A61K2236/17A61P11/00A61P11/04A61P31/14
Inventor 邹明明胡贤德徐满
Owner JIANGXI GROUNDIONG PHARM CO LTD
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