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Intestinal microorganism separating device and separating method

A technology of intestinal microorganisms and separation devices, which is applied in the field of microbial separation devices and intestinal microorganisms separation devices, can solve the problems that automation equipment cannot achieve anaerobic environment and is difficult to accept, so as to reduce the probability of possible contact with oxygen , reduce odor pollution and noise pollution, and reduce the effect of possibility

Pending Publication Date: 2019-03-26
SHANGHAI BIOTECAN PHARMA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, the isolation of intestinal flora adopts manual separation methods, and it is difficult for medical staff to accept visually, olfactorily or psychologically when preparing fecal suspension; and some automated equipment cannot achieve anaerobic environment

Method used

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  • Intestinal microorganism separating device and separating method
  • Intestinal microorganism separating device and separating method
  • Intestinal microorganism separating device and separating method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] The intestinal microorganism separation device provided in the specific embodiment is used to perform microorganism separation operation on the feces of healthy personnel to be collected. The operation steps include adding liquid, stirring, filtering and subpackaging. The specific process steps are as follows:

[0091] (1) Liquid addition: the healthy personnel to be sampled will put the feces into the original tank 1 and tighten it, and the medical staff will install the original tank 1 containing the feces to the host; open the first switch control valve 9, the second switch control Valve 10 and the third on-off control valve 11 feed inert gas into the first inert gas inlet 102 on the top of the raw material tank 1 to create an oxygen-free environment in the separation device, and close the first on-off control valve 9 and 9 in the separation device after 1 min. The second on-off control valve 10 and the third on-off control valve 11; the physiological saline in the li...

Embodiment 2

[0109] The intestinal microorganism separation device provided in the specific embodiment is used to perform microorganism separation operation on the feces of healthy personnel to be collected. The operation steps include adding liquid, stirring, filtering and subpackaging. The specific process steps are as follows:

[0110] (1) Liquid addition: the healthy personnel to be sampled will put the feces into the original tank 1 and tighten it, and the medical staff will install the original tank 1 containing the feces to the host; open the first switch control valve 9, the second switch control Valve 10 and the third on-off control valve 11 feed inert gas to the first inert gas inlet 102 on the top of the original tank 1 to create an oxygen-free environment in the separation device, and close the first on-off control valve 9, The second on-off control valve 10 and the third on-off control valve 11; the physiological saline in the liquid storage bottle 5 is introduced in the origin...

Embodiment 3

[0132] The intestinal microorganism separation device provided in the specific embodiment is used to perform microorganism separation operation on the feces of healthy personnel to be collected. The operation steps include adding liquid, stirring, filtering and subpackaging. The specific process steps are as follows:

[0133] (1) Liquid addition: the healthy personnel to be sampled will put the feces into the original tank 1 and tighten it, and the medical staff will install the original tank 1 containing the feces to the host; open the first switch control valve 9, the second switch control Valve 10 and the third on-off control valve 11 feed inert gas to the first inert gas inlet 102 on the top of the original tank 1 to create an oxygen-free environment in the separation device, and close the first on-off control valve 9, The second on-off control valve 10 and the third on-off control valve 11; the ultrapure water in the liquid storage bottle 5 is introduced in the original ta...

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Abstract

The invention provides an intestinal microorganism separating device and separating method. The separating device comprises a feeding unit, a filtering unit and a split charging unit which are sequentially connected from top to bottom; the feeding unit comprises a raw material tank, and a stirring device is fixed to the bottom of the raw material tank; the split charging unit comprises a bacterialliquid storage tank; the separating device comprises a vacuumizing device which is connected with a negative pressure connector of the bacterial liquid storage tank; the separating device further comprises a deodorization unit, and the deodorization unit is connected with a bad smell outlet of the raw material tank and the vacuumizing tank. The feeding unit, the multi-stage filtering unit and thesplit charging unit in the separating device are vertically distributed, and by additionally arranging a vacuum pump, an excrement raw material can flow to the next stage under action of gravity andnegative pressure, so that the phenomenon of blocking in a filtering process is greatly reduced.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and relates to a separation device and a separation method, in particular to a separation device and a separation method of microorganisms, in particular to a separation device and a separation method of intestinal microorganisms. Background technique [0002] The flora in the intestinal tract of normal people has been considered as a special organ in the human body, and fecal microbiota transplantation is considered a special organ transplantation. There are about 1,000 to 1,050 species of bacteria in the gut. At present, the functions of most of these bacteria and the mechanism by which different bacteria work organically are still unclear. In recent years, modern medicine has increasingly recognized the important role of intestinal bacteria in the human body, and has taken maintaining or rebuilding the normal intestinal flora of the human body as an important treatment for many disease...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/12C12M1/02C12M1/00C12N1/02
CPCC12M27/02C12M33/14C12M47/02C12N1/02
Inventor 王博伟张宇婷韩永俊刘亚
Owner SHANGHAI BIOTECAN PHARMA
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