Noninvasive nephrosis diagnosis and treatment system

Abstract

The invention discloses a noninvasive nephrosis diagnosis and treatment system which comprises a nephrosis diagnosis and treatment chip, an artificial intelligence model and a decision tree model. Thenephrosis diagnosis and treatment chip comprises a chip carrier; the chip carrier is a cube structure which is produced by adopting a polypropylene material and has a length of 3cm, a width of 1.5cmand a height of 7mm; a conical hole with a diameter of 1cm and a depth of 5mm is formed on the upper top surface of the chip carrier; the conical hole is filled with activation fluid with fluorescentcoded microspheres; the surface of the chip carrier is coated with a high-density polyethylene material to seal the conical hole; the artificial intelligence model adopts a logistic regression model;the decision tree model adopts a C5.0 algorithm decision tree model. The noninvasive nephrosis diagnosis and treatment system has the advantages of noninvasion, high sensitivity, high efficiency, convenience, rapidness, good repeatability, simplicity for operation, low cost, high accuracy and the like; a detection report can be more efficiently interpreted; an accurate prediction result is provided; the potential risks are timely avoided; meanwhile, a personalized diagnosis and treatment solution is made for a patient.

Description

technical field [0001] The invention relates to the medical field, in particular to a non-invasive nephropathy diagnosis and treatment system. Background technique [0002] The current diagnostic and prognostic indicators of IgA nephropathy mainly include renal biopsy and blood, urine, and biochemical indicators. Although renal biopsy can accurately reflect kidney damage, it is an invasive operation that cannot be repeated in a short time. Urine and biochemical indicators are diagnostic and prognostic indicators for all nephropathy. They have low sensitivity for specific diagnosis and prediction of prognosis of IgA nephropathy, and they respond only after more damage to the kidneys. [0003] The pathogenesis of IgA nephropathy includes the formation of abnormally glycosylated IgA1 (galactose-deficient IgA1, Gd-IgA1), Gd-IgA1-specific antibody recognition and the formation of circulating immune complexes and deposition in the glomerular mesangium. IgA is a glycoprotein. Ther...

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Problems solved by technology

In addition, studies have found that there is a non-linear functional relationship between serum MBL concentration and prognosis in patients with IgA nephropathy, patients with IgA nephropathy with low serum concentrations (MBL levels<100ng / ml) have a higher risk than IgA nephropathy patients with normal serum MBL concentrations (100-3540ng / ml) Higher risk of prodromal infection and gross hematuria, and worse prognosis

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