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Earthworm protein for reducing blood sugar, improving microcirculation and eliminating diabetes complications and applications thereof

A technology of earthworm protein and diabetes, which is applied in the field of earthworm protein, can solve the problem of less application, and achieve the effects of lowering blood sugar, improving body immunity, and improving blood lipids

Inactive Publication Date: 2019-03-05
熊小利
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0029] At present, the application of traditional Chinese medicine in my country has been more and more recognized by the international community. Its various medicinal materials have significant curative effects, and there are many drugs for lowering blood sugar, blood pressure, and lipids. However, in actual application, only a few have significant curative effects Species, such as Gynostemma pentaphyllum, Cassia seed, etc., and the application of Cassia sophera L., which is mentioned in this application, is rarely used

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Cassia sophera L., Leguminosae Cassia sophera L..

[0052] Dioscorea, commonly known as yam. Perennial herb with vine stems, often purple, cylindrical roots, opposite leaves, oval or elliptical, milky white flowers, dioecious. Root tubers contain starch and protein. Dioscorea-medicinal part, species name: yam (yù), Latin scientific name: Dioscorea opposita Alias: yam, triangle, yam, yam, medicinal egg, potato, yam, Yuyan. Odor: (root) sweet, warm, flat, non-toxic. English names: nagaimo, yamaimo, Chinese yam, Japanese mountainyam, Korean yam; "Compendium of Materia Medica" records that yam was changed to potato medicine because of the Tang Dynasty's name Li Yu, and because of the name of Song Yingzong Zhao Shu, it was changed to yam for avoiding taboo. . Yam is one of the constituent medicines of Liuwei Dihuang Wan.

[0053] [1]Yam

[0054] "Materia Medica Seeking Truth": "It is suitable to be used in medicine for nourishing yin, and medicine for tonifying the spleen and...

Embodiment 2

[0077] A kind of earthworm protein for lowering blood sugar, lowering lipids, lowering blood pressure, improving microcirculation, and eliminating diabetic complications, which is characterized by being prepared by the following steps:

[0078] 1) Earthworm cleaning: Use live earthworms to remove impurities and dead and deteriorated earthworms. Put the earthworms into water with a pH of 4.9 for 12.5 minutes. At the same time, add 50g of salt and light for 2.5 hours to encourage the earthworms to remove the dirt from their bodies and clean the earthworms. Body surface; rinse the cleaned live earthworms, rinse with 28°C warm water to wash away excess water and impurities on the outer surface; 2) pulping: weigh the earthworms obtained in step 1) and place them in a container, Add 40 parts by weight, 10-20 parts of sodium citrate with a pH value of 5.0-5.3, and 20 parts of Chinese medicine compound powder. The Chinese medicine compound powder is: 10 parts of Chumong seeds, Wang Buliu ...

Embodiment 3

[0092] A kind of earthworm protein for lowering blood sugar, lowering lipids, lowering blood pressure, improving microcirculation, and eliminating diabetic complications, which is characterized by being prepared by the following steps:

[0093] 1) Earthworm cleaning: Use live earthworms to remove impurities and dead and deteriorated earthworms. Put the earthworms in water with a pH of 5.9 for 15 minutes. At the same time, add 50g of salt and light for 3 hours to encourage the earthworms to remove the dirt from their bodies and clean the earthworms. Body surface; rinse the cleaned live earthworms, rinse with 28°C warm water to wash away excess water and impurities on the outer surface; 2) pulping: weigh the earthworms obtained in step 1) and place them in a container, Add 50 parts by weight, 20 parts of sodium citrate with a PH value of 5.3, and 30 parts of Chinese medicine compound powder. The Chinese medicine compound powder is: 10 parts of Chu Mang seeds, 3 parts of Wang Buliu X...

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Abstract

The invention discloses an earthworm protein for reducing blood sugar, lipid and pressure, improving microcirculation and eliminating diabetes complications. The protein is prepared by the following steps: 1) performing a step of earthworm cleaning, namely a step of selecting live earthworms, removing impurities and dead earthworms, putting the live earthworms into water with a pH value of 4-5.8 for 10-15 minutes, adding 50 g of salt, and rinsing the cleaned live earthworms with warm water at 28 DEG C to remove excess water and impurities on the surfaces; 2) pulping; 3) filtering or centrifuging homogenate obtained in the step 2) to remove crude residues to obtain a homogenate solution, filtering the homogenate solution to obtain clarified liquid of more than 180 enzyme activity unit per milliliter, putting the clarified liquid into a sterilization container, injecting high-pressure CO2 gas, mechanically and fully stirring the clarified liquid to be treated for 3-8 min, releasing the pressure through output by a conductor pipe, wherein the solubility of the CO2 rapidly decreases after the pressure is reduced, filtering the clarified liquid to remove impurities, and precipitating for 12 hours to obtain a supernatant solution; and 4) drying the supernatant solution in a freeze dryer at minus 28 DEG C to obtain powder.

Description

Technical field [0001] The invention belongs to the field of health care products, and in particular relates to a ground dragon protein that reduces blood sugar, improves microcirculation, and eliminates complications and its application. Background technique [0002] Earthworm protein is extracted from Earthworm. It contains collagenase, plasmin, lumbrokinase, nucleic acid, trace elements and other components. Its molecular weight is 5000-10000, which is a short-chain small molecule substance. Earthworm extract (including Earthworm protein, etc.) has a wide range of effects on the coagulation system and fibrinolytic system in the body, which can significantly reduce the platelet adhesion rate in rats, prolong the formation of thrombosis in the body and dissolve thrombus in the body, and increase the brain of rats. Blood flow reduces cerebrovascular resistance. Earthworm extract can also improve the deformability of red blood cells in mice, thereby improving blood rheology and m...

Claims

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Application Information

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IPC IPC(8): A61K38/01A61K9/48A61P3/10A61P9/14A61P3/06A61P9/12A61K36/8969
CPCA23V2002/00A61K9/4808A61K9/4858A61K36/185A61K36/36A61K36/481A61K36/482A61K36/488A61K36/57A61K36/605A61K36/736A61K36/79A61K36/804A61K36/815A61K36/8945A61K36/8968A61K36/8969A61K38/012A23L33/17A23P10/30A61K2300/00A23V2200/3262A23V2200/328A23V2200/326A23V2200/324
Inventor 熊小利
Owner 熊小利
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