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Dermatitis antibacterial film-forming spray and preparation method thereof

A film-forming spray and dermatitis technology, applied in the field of antibacterial film-forming spray for dermatitis and its preparation, can solve the problems of complex pathogenesis of dermatitis, insignificant drug efficacy, easy withdrawal and the like, and achieve good broad-spectrum antibacterial ability , Protects and repairs the skin barrier, relieves itching symptoms

Inactive Publication Date: 2019-02-26
GUANGXI XINYE BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are mostly antihistamines and glucocorticoids on the market. Antihistamines are likely to cause symptoms such as drowsiness, dizziness, dry mouth, and skin photosensitivity. There are also reports of jaundice and extrapyramidal symptoms. Long-term use of glucocorticoids Withdrawal phenomenon is easy to occur after use, and the side effects are relatively large
[0004] Due to the complex pathogenesis of dermatitis, the efficacy of existing drugs is not obvious, so the research and development of new drugs has become the development trend of treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] An antibacterial film-forming spray for dermatitis, which contains bletilla striata gum, nisin and sodium alginate as main components. Specifically, the content of each component in every 100ml dermatitis antibacterial film-forming spray is as follows:

[0067] Bletilla striata glue 1.5g

[0068] Sodium Alginate 2.0g

[0069] Nisin 0.5g.

[0070] purified water margin.

[0071] The preparation method of above-mentioned dermatitis antibacterial film-forming spray, it may further comprise the steps:

[0072] Step 1. Weigh 2.0g of sodium alginate and add 20ml of purified water to swell, stir it in a water bath at 50°C to dissolve it completely, and obtain a sodium alginate solution, debubble after ultrasonication for later use;

[0073] Dissolve 1.5g of Bletilla striata gum in 80ml of purified water, soak it and stir it in a water bath at 65°C to obtain Bletilla striata gum solution;

[0074] Step 2. Mix the sodium alginate solution and the bletilla striata gum solu...

Embodiment 2

[0076] A kind of dermatitis antibacterial film-forming spray, the content of each component in every 100ml dermatitis antibacterial film-forming spray is as follows:

[0077] Bletilla striata glue 0.40g

[0078] Sodium Alginate 3.0g

[0079] Nisin 0.7g

[0080] Trehalose 0.08g

[0081] Allantoin 0.5g

[0082] Purified water balance.

[0083] The preparation method of above-mentioned dermatitis antibacterial film-forming spray, it may further comprise the steps:

[0084] Step 1. Weigh the above-mentioned amount of sodium alginate and add 40ml of purified water to swell, stir it in a water bath at 45°C to dissolve it completely, and obtain a sodium alginate solution, and debubble it for later use after ultrasonication;

[0085] Dissolve Bletilla striata gum in 60ml of purified water, soak and stir in a water bath at 70°C to obtain Bletilla striata gum solution;

[0086] Step 2. Mix sodium alginate solution and bletilla striata gum solution, add nisin, trehalose, and allant...

Embodiment 3

[0088] A kind of dermatitis antibacterial film-forming spray, the content of each component in every 100ml dermatitis antibacterial film-forming spray is as follows:

[0089] Bletilla striata glue 0.40g

[0090] Sodium alginate 0.05g

[0091] Nisin 0.05g

[0092] Trehalose 1.3g

[0093] Allantoin 0.5g

[0094] Berberine Hydrochloride 0.8g

[0095] Baicalin 0.5g

[0096] Concentrated Buffalo Horn Powder 1.2g

[0097] Peppermint Oil 1.8g

[0098] Purified water balance.

[0099] The preparation method of above-mentioned dermatitis antibacterial film-forming spray, it may further comprise the steps:

[0100] Step 1. Weigh sodium alginate and add 20ml of purified water to swell, stir in a water bath at 45°C to dissolve completely to obtain a sodium alginate solution, debubble after ultrasonication and set aside;

[0101] Dissolve Bletilla striata gum in 80ml of purified water, soak and stir in a water bath at 60°C to obtain Bletilla striata gum solution;

[0102] Step 2:...

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Abstract

The invention relates to the technical field of sprays and in particular relates to a dermatitis antibacterial film-forming spray and a preparation method thereof. Viewing from the point that skin isa basic barrier of human bodies, bletilla striata gelatin, nisin and sodium alginate are selected as main components, a bletilla striata gelatin-nisin-sodium alginate binary antibacterial commixed membrane is prepared under intermolecular or intramolecular actions among the main components, moisture evaporation and interstitial fluid exudation on the surface of skin are prevented, the play of a medicine effect is facilitated, and the healing of skin is achieved. By adopting the spray, skin lesion inflammation reactions caused by dermatitis and eczema can be rapidly alleviated, skin desquamation can be removed, newly born skin barriers after skin lesion can be protected and repaired, dryness and rahagades can be avoided, and thus itching symptoms can be well relieved.

Description

technical field [0001] The invention relates to the technical field of sprays, in particular to a dermatitis antibacterial film-forming spray and a preparation method thereof. Background technique [0002] The largest organ in the human body is the skin, which accounts for about 16% of the body weight. It is the first natural defense line of the human body against the invasion of external viruses and bacteria. The skin has barrier, absorption, secretion, excretion, metabolism, immunity, temperature regulation and sensory functions. Among them, the skin barrier function is the basis, that is, externally resists the invasion of antigenic substances, microorganisms, sunlight, etc., and internally prevents the loss of nutrients and water in the body. Loss, so that the skin maintains normal physiological functions and prevents the occurrence of skin diseases. If the barrier function of the skin is damaged, the water loss through the epidermis increases, the skin becomes dry and ...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K47/36A61K36/898A61K38/02A61P17/00
CPCA61K9/7015A61K36/898A61K38/02A61K47/36A61P17/00A61K2300/00
Inventor 雷艳
Owner GUANGXI XINYE BIOLOGICAL TECH
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