Method and device for protein feature extraction, function model generation, and function prediction

Abstract

The embodiment of the present application discloses a method and device for protein feature extraction, function model generation, and function prediction; the protein feature extraction method includes: obtaining the amino acid sequence of the target protein and the residue interaction site on the amino acid sequence of the target protein, Obtain the target amino acid sequence and target residue interaction site; intercept an amino acid abbreviation code or multiple consecutive amino acid abbreviation codes from the target amino acid sequence to obtain a target string including the target residue interaction site; extract the target string in the target The text features in the amino acid sequence, using the feature of the residue interaction site on the amino acid sequence as the expression of protein function, can provide high-quality feature input for the subsequent use of machine learning algorithms for protein function prediction, which is conducive to abandoning time-consuming The powerful manual prediction method improves the efficiency and accuracy of protein function prediction.

Description

technical field [0001] The present application relates to the field of biological information technology, and in particular to a method and device for protein feature extraction, function model generation, and function prediction. Background technique [0002] With the continuous development of life science research, people gradually realize that genome information can no longer fully explain and predict various life processes and phenomena. Proteins, as executors of cellular activity and functions, have received increasing attention. Knowing the function of proteins in advance will help to understand the mechanism of biochemical reactions in cells, and then guide drug design. [0003] The function of protein, specifically expressed as the interaction between protein and protein, protein and carbohydrate, protein and lipid, protein and deoxyribonucleic acid (DNA) or ribonucleic acid (Ribonucleic acid, RNA), protein and metal ion ability. In the past ten years, a variety o...

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Problems solved by technology

[0004] In view of this, the embodiment of the present application provides a method and device for protein feature extraction on the one hand, a method and device for generating protein function models on the other hand, and a method for protein function prediction on the other hand It can solve the problem that using biological experiment technology to predict protein function in the prior art will consume a lot of manpower and time, and can efficiently and accurately grasp the function of protein

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