Anisotropic conductivity head model modeling method and device combined with cortical excitability

Abstract

The invention relates to the field of transcranial magnetic stimulation head model modeling, in particular to an anisotropic conductivity head model modeling method and device combined with cortical excitability. The method includes: establishing an anisotropic conductivity head model based on MRI and DTI images; obtaining an individual cortical excitability comprehensive index through an array target TMS experiment; and constructing an anisotropic conductivity head model containing the cortical excitability according to the anisotropic conductivity head model and the individual cortical excitability comprehensive index. The transcranial magnetic stimulation head model modeling method is combined with functional information on the basis of structural information, reflects the cortical excitability of an individual, is close to a real brain, can further improve the authenticity and reliability of the TMS modeling simulation, has important research significance in simulating the effect of TMS, optimizing TMS coils and stimulation parameters, and has good development and application prospect.

Description

technical field The invention relates to the field of model modeling of a transcranial magnetic stimulation head, in particular to a modeling method and device for an anisotropic conductivity head model combined with cortical excitability. Background technique Transcranial magnetic stimulation is a non-invasive neurostimulation technology, widely used in the research of brain function, brain network and brain circuit. This technology uses the changing magnetic field generated by the pulse current to act on the brain tissue to generate an induced electric field. When the induced electric field in the brain tissue area reaches or exceeds a certain threshold, it can activate or inhibit the neural activity in this area. TMS simulation research is an important means to predict TMS effect, optimize TMS coil and stimulation parameters. The accurate establishment of the TMS head model is the basis for the simulation calculation of the TMS intracranial field distribution. The curr...

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Problems solved by technology

The purpose of the present invention is to solve the shortcomings in the prior art that cannot reflect the differences in cortical excitability of different individuals, and propose an anisotropic conductivity head model modeling method and device combined with cortical excitability

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