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Multifunctional liquid band-aid and preparation method thereof

A Band-Aid, multi-functional technology, applied in the field of medical devices, can solve the problems of no obvious antibacterial effect, no antibacterial ingredients, pungent odor, etc., achieve good waterproof and breathable performance, promote wound healing, and have no skin irritation. Effect

Inactive Publication Date: 2018-11-13
FUZHOU GENERAL HOSPITAL OF NANJING MILITARY COMMAND P L A
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Take the most well-known Japanese Kobayashi Liquid Band-Aid as an example. As a film-forming material, nitrocellulose has good waterproof and air permeability, but has disadvantages such as pungent smell and no obvious antibacterial effect; domestic liquid Band-Aid related patents also have various deficiencies: Using water as a solvent, the film forming speed is slow and inconvenient to use (201410616668.9, 201510484327.5); Contains ether, has a bad smell, and is prone to safety problems during the production process (201510776194.9, 201610004155.1, 201610583947.9); No antibacterial ingredients, and the antibacterial effect is unknown (201610578173.0, 201610560489.7); Contains growth factors, high cost, unstable, variable and inactivated, difficult to store (201510416237.2, 201510070878.7)
[0003] In the above-mentioned prior art, the basic requirements of liquid band-aids are met, but there is no technology for adding analgesics to relieve wound pain

Method used

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  • Multifunctional liquid band-aid and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] A preparation method of a multifunctional liquid band-aid, comprising the steps of:

[0039]In parts by weight, 50 parts of isopropyl alcohol, 20 parts of ethyl acetate, 5 parts of propyl acetate, 2 parts of lidocaine, 0.5 part of vitamin E, 10 parts of isopropyl palmitate, Mix 4 parts of castor oil, 0.3 parts of camphor, 2 parts of tributyl citrate, 0.1 part of peppermint oil and 0.1 part of clove bud oil, then add 6 parts of nitrocellulose, seal it, and let it stand at 20°C Allow it to fully swell for 12 hours, then at room temperature, control the stirring speed to 90 r / min, and stir until clear, transparent and uniform.

Embodiment 2

[0040] Example 2 (without adding vitamin E)

[0041] A preparation method of a multifunctional liquid band-aid, comprising the steps of:

[0042] In parts by weight, with 50.5 parts of isopropyl alcohol, 20 parts of ethyl acetate, 5 parts of propyl acetate, 2 parts of lidocaine, 10 parts of isopropyl palmitate, 4 parts of castor oil, Mix 0.3 parts of camphor, 2 parts of tributyl citrate, 0.1 part of peppermint oil and 0.1 part of clove bud oil, then add 6 parts of nitrocellulose, seal it, and let it stand at 20°C for 12 hours to fully swell, Then at room temperature, control the stirring speed to 90 r / min, and stir until clear, transparent and homogeneous.

Embodiment 3

[0044] A preparation method of a multifunctional liquid band-aid, comprising the steps of:

[0045] In parts by weight, 40 parts of isopropyl alcohol, 20 parts of ethyl acetate, 5 parts of propyl acetate, 2 parts of lidocaine, 0.5 part of vitamin E, 16 parts of isopropyl palmitate, Mix 4 parts of castor oil, 0.3 parts of camphor, 2 parts of tributyl citrate, 0.1 part of peppermint oil and 0.1 part of clove bud oil, then add 10 parts of nitrocellulose, seal it, and let it stand at 20°C Allow it to fully swell for 12 hours, then at room temperature, control the stirring speed to 90 r / min, and stir until clear, transparent and uniform.

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Abstract

The invention provides a multifunctional liquid band-aid and a preparation method thereof, and relates to the field of medical treatment and public health. The multifunctional liquid band-aid comprises the following raw materials in parts by weight: 5-15 parts of a film-forming material, 0.1-4 parts of a local anesthetic, 0.5-1.5 parts of an antioxidant, 2-15 parts of a plasticizer, 1-20 parts ofa skin emollient, 0.1-1 part of an aromatic agent and 20-85 parts of a fast-drying solvent. The invention has the following characteristics: the prepared liquid band-aid is adhesive, can form a film at the wound quickly, and has excellent waterproofness; the local anesthetic lidocaine and the antioxidant vitamin E play a synergistic role to relieve wound pain, effectively inhibit bacteria and accelerate wound healing; the liquid band-aid is applicable to various complex-shaped wounds and has a certain toughness and permeability; the formed film is transparent and regular so that the wound healing conditions can be observed at any time; and the liquid band-aid provided by the invention has high safety, no toxicity and no obvious skin irritation.

Description

technical field [0001] The invention belongs to the field of medical devices and relates to a liquid band-aid, in particular to a multifunctional liquid band-aid and a preparation method thereof. Background technique [0002] Skin injuries are very common in life, and band-aids are often used for wound treatment. However, ordinary band-aids are not waterproof and breathable, and long-term coverage may cause wound ulceration; the shape is fixed, and it is not easy to stick to narrow places and joints, so it cannot be applied to wounds in various parts; when the band-aid is torn off, it may cause secondary damage to the wound and pain. Therefore, an ideal Band-Aid should have the advantages of waterproof, breathable, pain relief, antibacterial, stretchable, tensile, easy to paste, does not affect joint movement, does not need to be removed, and has a good smell. In recent years, there have been many studies on liquid band-aids. Before use, they are in liquid form. After bein...

Claims

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Application Information

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IPC IPC(8): A61L26/00
CPCA61L26/0023A61L26/0057A61L26/0061A61L26/0066A61L2300/204A61L2300/402A61L2300/45C08L1/18
Inventor 宋洪涛张灵娜陶春张敏新刘志宏陈旭曾令军张佳良刘琳琳
Owner FUZHOU GENERAL HOSPITAL OF NANJING MILITARY COMMAND P L A
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