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Application of fipronil and insect growth regulator, anti-ectoparasite animal compound external preparation and preparation method of external preparation

A technology for growth regulators and ectoparasites, applied in the field of animal compound external preparations against ectoparasites and its preparation, can solve problems such as doubts about product performance, affecting the deworming effect of preparations, and affecting confidence in use

Inactive Publication Date: 2018-11-13
FOSHAN NANHAI EASTERN ALONG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This phenomenon not only affects the actual insect repellent effect of the preparation, but also easily leads users to doubt the product performance and affects the confidence of subsequent use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] The present invention provides a compound external preparation for animals against ectoparasites, which is a spray consisting of the following components in parts by weight: 0.25 parts of fiprenil, 0.05 parts of pyriproxyfen, and 5 parts of glyceryl caprate , 0.02 parts of BHA, 0.01 parts of BHT, 0.5 parts of clary sage and the balance of benzyl alcohol.

[0047] The preparation method of the animal compound external preparation against ectoparasites is as follows: put benzyl alcohol into a reaction tank, add fiprenil, pyriproxyfen, BHA and BHT, stir and dissolve; add caprylic glyceride, and mix evenly; Add water and clary sage essential oil, mix well and serve.

Embodiment 2

[0049] The invention provides a compound external preparation for animals against ectoparasites, which is a spray and consists of the following components in parts by weight: 0.1 part of fiprenil, 0.01 part of pyriproxyfen, 0.6 part of jojoba oil, 0.01 part of BHA, 0.01 part of BHT, 0.1 part of lemongrass essential oil and the balance of benzyl alcohol.

[0050] The preparation method of the compound external preparation for animals against ectoparasites is as follows: put benzyl alcohol into a reaction tank, add fiprenil, pyriproxyfen, BHA and BHT, stir and dissolve; add jojoba oil, mix evenly; add Water and lemongrass essential oil, mix well and serve.

Embodiment 3

[0052] The invention provides a compound external preparation for animals against ectoparasites, which is a spray and consists of the following components in parts by weight: 8 parts of fiprenil, 5 parts of pyriproxyfen, and 8 parts of isopropyl myristate parts, 0.02 parts of BHA, 5 parts of propylene carbonate and the balance of diethylene glycol ether.

[0053] The preparation method of the animal compound external preparation of the antibody ectoparasite is: put into the reaction tank the whole amount of diethylene glycol ether, add the whole amount of fiprenil, pyriproxyfen, BHA, stir and dissolve; add the whole amount of meat Isopropyl myristate and propylene carbonate are mixed evenly.

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PUM

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Abstract

The invention discloses an application of fipronil and an insect growth regulator to an anti-ectoparasite animal compound external preparation. The anti-ectoparasite animal compound external preparation comprises the fipronil and the insect growth regulator, and the weight ratio of the fipronil to the insect growth regulator is (0.1-20):(0.01-15). The preparation method includes the step: uniformly mixing the fipronil, the insect growth regulator and acceptable accessories. The anti-ectoparasite animal compound external preparation can effectively block a gamma-aminobutyric acid regulation chloride ion channel of an insect central nervous system, interfere the insect central nervous system and induce over-excitation of insect nerves and muscles until death, unhatched or ametabolic larvae cannot emerge into adults and die, and more complete overall expelling and killing effects of the preparation are ensured. Moreover, the preparation can more rapidly enter bodies to generate effects, and efficacy can be rapidly achieved.

Description

technical field [0001] The invention relates to the technical field of veterinary drug preparations, in particular to the application of fiprenil and an insect growth regulator, a compound external preparation for animals against ectoparasites and a preparation method thereof. Background technique [0002] The pet market is developing rapidly. According to a survey by the American Pet Products Association, in 2005, the pet industry in the United States spent more than 36 billion U.S. dollars, which nearly doubled to more than 60 billion U.S. dollars in 2015. Antiparasitic drugs have the highest sales share among pet drugs. According to the American Pet Products Association, Americans spent about $30 billion on veterinary medicine in 2015, of which antiparasitic drugs accounted for the highest sales volume. An earlier survey data showed that among the 158 new varieties of veterinary drugs approved by the US FDA from 2002 to 2006, there were 32 anti-parasitic drugs, accountin...

Claims

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Application Information

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IPC IPC(8): A61K45/06A61K31/415A61K31/4402A61K31/44A61K31/175A61K9/12A61K47/44A61K47/10A61P33/14
CPCA61K9/0014A61K9/12A61K31/175A61K31/415A61K31/44A61K31/4402A61K45/06A61K47/10A61K47/44A61P33/14A61K2300/00
Inventor 元晓琪陈静虹林孝崇焦晓军孙迎
Owner FOSHAN NANHAI EASTERN ALONG PHARMA CO LTD
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