Application of melanin extracted from auricularia auricula in liver-protection product

A technology of melanin and black fungus, applied to the application field of melanin in liver protection products, can solve the problems of easy rebound, insignificant effect of aspartate aminotransferase, elevated aspartate aminotransferase, etc.

Pending Publication Date: 2018-09-18
FUJIAN AGRI & FORESTRY UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Also have some untoward reactions as described Chinese medicine preparation, although the schisandra extract wherein can effectively reduce the level of the alkaline phosphatase in the serum, but, easy rebound after drug withdrawal, the effect to aspartate aminotransferase is not obvious, some patients with chronic liver disease Elevation of aspartate aminotransferase after taking
Furthermore, the long-term curative effect is poor

Method used

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  • Application of melanin extracted from auricularia auricula in liver-protection product
  • Application of melanin extracted from auricularia auricula in liver-protection product
  • Application of melanin extracted from auricularia auricula in liver-protection product

Examples

Experimental program
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Effect test

Embodiment 1

[0041] The melanin extracted from the black fungus is used in the hepatoprotective medicine to make a tablet; the melanin accounts for 0.1% by weight of the hepatoprotective medicine, and other ingredients are auxiliary materials.

Embodiment 2

[0043] The melanin extracted from the black fungus is used in the hepatoprotective medicine to prepare granules; the melanin accounts for 50.0% by weight of the hepatoprotective medicine, and other components are auxiliary materials.

Embodiment 3

[0045] The melanin extracted from the black fungus is used in the hepatoprotective medicine to make capsules; the melanin accounts for 75% by weight of the hepatoprotective medicine, and other components are auxiliary materials.

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PUM

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Abstract

The invention discloses application of melanin extracted from auricularia auricula in a liver-protection product, and belongs to the technical field of medicines and food. According to the applicationdisclosed by the invention, protein in an auricularia auricula fruiting body is destroyed through strong acid, and the melanin is precipitated out through an alkali solution to obtain precipitants, and the precipitants are collected so as to obtain a melanin crude extract; purifying the melanin crude extract by sequentially using ethanol, ethyl acetate and acetone to obtain the purified melanin;using the melanin in a liver-protection product (including a liver-protection medicine or liver-protection food), wherein the melanin component accounts for 0.1 to 100 percent by weight of the liver-protection product. According to the application of the melanin extracted from the auricularia auricula in the liver-protection product disclosed by the invention, the melanin extracted from the auricularia auricula is used in the liver-protection product, so that the effective liver-protection component, namely the melanin, has obvious effects on prevention or treatment of virus hepatitis, drug-induced liver injury, alcohol liver and fatty liver. In addition, the application of the melanin extracted from the auricularia auricula in the liver-protection product disclosed by the invention has the advantages of simple and feasible process and low cost, and is suitable for industrially mass production.

Description

technical field [0001] The invention belongs to the technical field of medicine and food, and in particular relates to the application of melanin extracted from black fungus in liver protection products. Background technique [0002] Melanin is a heterogeneous polymer compound formed by oxidative polymerization of indole or phenolic compounds. It is generally black, brown or brown. It exists widely in animals, plants and microorganisms and has a wide range of biological functions. Natural melanin has The effects of nourishing, health preservation, anti-oxidation and anti-aging have aroused people's strong interest, but there are few reports on the research of melanin produced by edible fungi at home and abroad. At present, due to the impact of environmental pollution and drugs, liver-related diseases are on the rise. Severe hepatitis, liver fibrosis, and cirrhosis account for a large proportion of the population. Liver diseases have become a serious threat to human health. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/07A61P1/16A61P31/14A61P31/20A23L31/00A23L33/00A61K31/36
CPCA23L31/00A23L33/00A23V2002/00A61K31/36A61K36/07A61K2236/33A61K2236/53A61P1/16A61P31/14A61P31/20A61K2300/00A23V2200/30A23V2250/208A23V2300/14
Inventor 傅俊生戚梦侯若琳刘鑫刘城移刘建兵林文雄
Owner FUJIAN AGRI & FORESTRY UNIV
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