Application of extract of radix astragali in treating cadmium-induced diabetic nephropathy
A technology of astragalus extract and diabetic nephropathy, applied in the field of pharmacology, can solve the problems of lack of treatment methods, late discovery, difficult reversal of lesions, etc., and achieve a significant protective effect.
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[0018] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.
[0019] 1. Animal preparation
[0020] 70 male Kunming mice.
[0021] 2. Animal model construction and group processing
[0022] 1. Grouping
[0023] The mice were randomly divided into 7 groups with 10 mice in each group. They were normal control group (group K), cadmium-induced model group (group M), astragalus protection group I (group H), positive drug control group I (group Y), STZ control group (group S), and astragalus protection group II (H2 group), positive drug control group II (Y2 group), see Table 1.
[0024] 2. Protective drugs
[0025] 1) Preparation of Astragalus extract
[0026] The Radix Astragali is crushed, passed through a 40-mesh sieve, 10g of the medicinal material is taken, pre-soaked in water for 8 hours, and extracted twice with water as a solvent under reflux (about 100°C), and 10 times the amount of the medicinal material...
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