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Glucosyl core-shell structure carrier material, preparation and application thereof

A carrier material, dextran-based shell technology, which can be used in applications, preparations for skin care, medical preparations with inactive ingredients, etc., and can solve the problems of complex production process, high loss of raw materials, and low yield of carrier complexes. , to achieve the effects of controllable reaction conditions, simple steps and excellent biocompatibility

Active Publication Date: 2018-08-21
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the yield of the obtained complex is low, the loss of raw materials is large, and the production process is relatively complicated.

Method used

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  • Glucosyl core-shell structure carrier material, preparation and application thereof
  • Glucosyl core-shell structure carrier material, preparation and application thereof
  • Glucosyl core-shell structure carrier material, preparation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] 1 g of water-soluble starch particles was weighed and dissolved in Tris-HCl buffer solution (50 mmol / L, pH 7.0) to prepare a homogeneous solution with a mass concentration of 0.5%. Continue to add 1.5 g of glucose-1-phosphate and 40 U of glycosyltransferase, stir evenly, and react at a constant temperature of 40° C. and pH 7.0 for 12 hours. Heat to inactivate the enzyme and centrifuge, and vacuum-dry the obtained precipitate to obtain the glucosyl-core-shell structure carrier material.

[0043] like figure 1As shown, a represents spherical hyperbranched water-soluble starch particles; b represents the initial stage of graft chain extension of starch particles modified by biotechnology, that is, glycosyltransferase connects the glucose group to the Non-reducing ends of spherical starch granules. c indicates that starch particles have been modified by biotechnology, and the late stage of graft chain extension, that is, the linear structure formed by grafting is wound an...

Embodiment 2

[0048] 1 g of water-soluble starch particles was weighed and dissolved in Tris-HCl buffer solution (50 mmol / L, pH 7.0) to prepare a homogeneous solution with a mass concentration of 1.0%. Continue to add 2.5 g of glucose-1-phosphate and 60 U of glycosyltransferase, stir evenly, and react at a constant temperature of 40° C. and pH 7.0 for 18 hours. Heat to inactivate the enzyme and centrifuge, and vacuum-dry the obtained precipitate to obtain the glucosyl-core-shell structure carrier material.

Embodiment 3

[0050] 1 g of water-soluble starch particles was weighed and dissolved in Tris-HCl buffer solution (50 mmol / L, pH 7.0) to prepare a homogeneous solution with a mass concentration of 1.5%. Continue to add 5.0 g of glucose-1-phosphate and 100 U of glycosyltransferase, stir evenly, and react at a constant temperature of 40° C. and pH 7.0 for 24 hours. Heat to inactivate the enzyme and centrifuge, and vacuum-dry the obtained precipitate to obtain the glucosyl-core-shell structure carrier material.

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Abstract

Belonging to the technical field of modern food processing, the invention discloses a glucosyl core-shell structure carrier material, preparation and application thereof. According to the invention, spherical hyperbranched water-soluble starch particles are adopted as the raw materials, an enzymatic grafting chain extension process is employed for treatment to modify the surface of a water-solubleglucan molecule into a solid shell structure with densely accumulated crystalline structures, thereby forming the glucosyl core-shell structure carrier material with "an amorphous state inner core cavity and a crystalline state outer shell layer". The spherical hyperbranched water-soluble starch particles adopted by the invention have wide raw material sources, and are not restricted by production places and seasons; the steps are simple and easy to operate, the reaction conditions are controllable, the cost is relatively low, and basically no pollution is caused to the environment; the product prepared by the method provided by the invention can effectively protect, transfer and release functional nutrients, can be applied to food, medicine, daily chemicals and other fields, and has verygood market prospects and broad economic benefits.

Description

technical field [0001] The invention relates to a carrier material with a glucosyl shell core structure and its preparation and application, belonging to the technical field of modern food processing. Background technique [0002] With the development of social technology and economy, the transformation of lifestyle and the deterioration of the environment, the spectrum of diseases in our country has changed. The number of chronic diseases such as diabetes, hypertension, and obesity has increased sharply, and the number of sub-healthy people is also increasing. At the same time, people's awareness of health care is becoming stronger and stronger, and the concept of medical treatment has changed from the type of after-treatment to the type of preventive care. People are paying more and more attention to the prevention of chronic diseases through a healthy lifestyle and dietary nutrition. [0003] Due to their remarkable physiological functions, functional foods have become a...

Claims

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Application Information

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IPC IPC(8): C12P19/18C12P19/08C12P19/04A23L33/26A23P10/30A61K9/51A61K47/36A61K8/11A61K8/73A61Q19/00
CPCA23V2002/00A61K8/11A61K8/73A61K8/732A61K9/5161A61Q19/00A23L33/26A23P10/30C12P19/04C12P19/08C12P19/18A23V2200/224A23V2200/30A23V2250/5042
Inventor 缪铭江波齐阳金征宇陈琛张涛
Owner JIANGNAN UNIV
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