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A kind of graphene antihypertensive patch and preparation method thereof

A graphene and blood pressure-lowering technology, which is applied in the direction of pharmaceutical formulations, other medical devices, cardiovascular system diseases, etc., can solve problems such as toxic side effects, impact on human health, and impact, and achieve a good blood pressure lowering effect and enhance the body's immunity Effect

Active Publication Date: 2021-03-26
GUANGXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the market, antihypertensive drugs include two kinds of oral administration and external use. , but all have certain toxic and side effects, which may affect other complications and affect human health; and most of the externally used medicinal patches have the problem of poor efficacy and inconspicuous efficacy, and cannot really achieve the purpose of lowering blood pressure

Method used

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  • A kind of graphene antihypertensive patch and preparation method thereof

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Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1: a kind of graphene antihypertensive patch, comprises medicine patch bottom liner and administration layer, is coated with the first layer of graphene nano-layer on the medicine patch bottom liner, is coated with drug administration layer on the first layer of graphene nano-layer layer, the drug delivery layer is coated with a second layer of graphene nano-layers, wherein the drug delivery layer includes the following components by weight of traditional Chinese medicine:

[0029] 30 parts of Cyclocarya paliurus; 25 parts of Mulberry; 18 parts of Chuanxiong; 15 parts of Pueraria lobata; 8 parts of wild chrysanthemum; 6 parts of dandelion; 7 parts of camellia oil; 5 parts of Moutan bark; 4 parts of Poria; ; 2 parts of mulberry leaves; 1 part of osmanthus leaves.

[0030] The first layer of graphene nanolayer and the second layer of graphene nanolayer include the following components by weight: 80 parts of graphene; 5 parts of 2-(3,4-epoxycyclohexane) ethyltri...

Embodiment 2

[0036] Embodiment 2: A kind of graphene antihypertensive patch comprises a drug patch backing and a drug delivery layer, the first layer of graphene nano-layer is coated on the drug patch backing, and the first layer of graphene nano-layer is coated with a drug delivery layer. layer, the drug delivery layer is coated with a second layer of graphene nano-layers, wherein the drug delivery layer includes the following components by weight of traditional Chinese medicine:

[0037]20 parts of Cyclocarya paliurus; 20 parts of Mulberry; 10 parts of Rhizoma Chuanxiong; 10 parts of Pueraria lobata; 5 parts of wild chrysanthemum; 5 parts of dandelion; 5 parts of camellia oil; 3 parts of Moutan bark; ; 1 part mulberry leaf; 1 part laurel leaf

[0038] The first layer of graphene nanolayer and the second layer of graphene nanolayer include the following components by weight: 80 parts of graphene; 5 parts of 2-(3,4-epoxycyclohexane) ethyltrimethoxysilane; 2 parts of triethoxy-1H,1H,2H,2H-...

Embodiment 3

[0044] Embodiment 3: A kind of graphene lowering blood pressure sticks, comprises medicine patch backing and administration layer, is coated with the first layer of graphene nano-layer on the medicine patch backing, is coated with drug-administering layer on the first layer of graphene nano-layer layer, the drug delivery layer is coated with a second layer of graphene nano-layers, wherein the drug delivery layer includes the following components by weight of traditional Chinese medicine:

[0045] 40 parts of Cyclocarya paliurus; 30 parts of Mulberry; 20 parts of Chuanxiong; 20 parts of Pueraria lobata; 10 parts of wild chrysanthemum; 8 parts of dandelion; 8 parts of camellia oil; 5 parts of Moutan bark; ; 2 parts of mulberry leaves; 2 parts of osmanthus leaves.

[0046] The first layer of graphene nanolayer and the second layer of graphene nanolayer include the following components by weight: 80 parts of graphene; 5 parts of 2-(3,4-epoxycyclohexane) ethyltrimethoxysilane; 2 p...

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Abstract

The invention discloses a graphene blood pressure lowering plaster and a preparation method thereof. The graphene blood pressure lowering plaster comprises a medicine plaster bottom liner and a medication layer, wherein a first graphene nanometer layer is covered on the medicine plaster bottom liner; the medication layer is covered on the first graphene nanometer layer; a second graphene nanometerlayer is covered on the medication layer, wherein the medication layer is prepared from folium cyclocaryae paliuri, herba taxilli, rhizoma chuanxiong, radix puerariae, wild chrysanthemum flowers, herba taraxaci, camellia oil, glossy ganoderma, corn stigma, cortex moutan, poria cocos, mulberry leaves and cherry bay leaves; the graphene nanometer layer is prepared by using a graphene nanometer sheet as a substrate material and mixing 2-(3,4-cyclohexene oxide)ethyltrimethoxysilane, triethoxy-1H,1H,2H,2H-tridecafluoro-N-octylsilane, 3-dimethylamino-1,2-propanediol, dodecyl polyethylene glycol ammonium sulfate and ethyl hexyl lactate. The graphene blood pressure lowering plaster is safe and nontoxic, and has no influence on the human body health; a user can recover at a short time; the rehabilitation rate is about 100 percent; the graphene blood pressure lowering plaster is suitable for being widely popularized.

Description

technical field [0001] The invention relates to a blood pressure-lowering patch, and more specifically relates to a graphene blood-pressure-lowering patch and a preparation method thereof. Background technique [0002] With the rapid development of the economy, people's lives are getting better and better, but at the same time, people's pressure is also increasing. In order to relieve the pressure, people often smoke or drink too much, and their eating habits are also poor. They often eat and drink too much, and don't pay attention Exercising, these all lead to high blood pressure is one of the common diseases of modern people; high blood pressure mainly damages human blood. It can promote the hardening of the arterial wall and the narrowing of the lumen—that is, the so-called "arteriosclerosis". If hypertension is combined with diabetes, it will accelerate and aggravate the damage of blood vessels and make the condition worsen rapidly. It should be treated actively. [000...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K36/899A61K47/04A61P9/12A61M37/00
CPCA61K9/7023A61K36/074A61K36/076A61K36/185A61K36/236A61K36/287A61K36/288A61K36/488A61K36/52A61K36/605A61K36/63A61K36/65A61K36/71A61K36/82A61K36/899A61K47/02A61M37/00A61M2037/0007A61P9/12A61K2300/00
Inventor 赵立春
Owner GUANGXI UNIV OF CHINESE MEDICINE
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