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Oral liquid containing radix acanthopanacis senticosi and method for extracting eleutherosides from radix acanthopanacis senticosi

A technology of total glucosides and extraction methods of Acanthopanax senticosus, which is applied in the directions of pharmaceutical formulations, dispersion liquid delivery, medical preparations containing active ingredients, etc. , do not pay attention to sample pretreatment and other issues, to achieve the effect of good medicinal activity, simple and feasible operation, and short extraction time

Inactive Publication Date: 2018-07-13
国草(大连)生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

During the extraction process, no attention was paid to sample pretreatment, and the decoction time and decoction method were single, which to a certain extent prevented the dissolution of various active ingredients in Panax ginseng, resulting in low or unbalanced active ingredient content in the extract, or even high impurity content

Method used

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  • Oral liquid containing radix acanthopanacis senticosi and method for extracting eleutherosides from radix acanthopanacis senticosi
  • Oral liquid containing radix acanthopanacis senticosi and method for extracting eleutherosides from radix acanthopanacis senticosi

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] A method for extracting eleutherosides from Acanthopanax ginseng, the steps are as follows:

[0039] Step a, five ginseng raw material pretreatment:

[0040] a1: Select fresh raw materials of Wujiaginseng, clean them and dry them in a vacuum drying oven at 60-65°C for 10-15 hours, and crush the fully dried raw materials of Wujiaginseng into 50-100 meshes;

[0041] a2: Add petroleum ether to the Wujiashen powder obtained in step a1, the mass volume ratio of the Wujiashen powder to petroleum ether is 1g:5-10mL, reflux and extract for 2-3h, filter and remove the filtrate, and put the filter residue into Dry in a vacuum oven at 50°C for 30 minutes to volatilize the solvent, and obtain the defatted Wujiaginseng powder from which the fat-soluble impurities in the chlorophyll have been removed;

[0042] Step b, high-pressure extraction of total eleutherosides in defatted Radix Acanthopanax ginseng powder:

[0043] b1: Add 40% ethanol solution to the defatted Wujiashen powder...

Embodiment 2

[0053] A method for extracting eleutherosides from Acanthopanax ginseng, the steps are as follows:

[0054] Step a, five ginseng raw material pretreatment:

[0055] a1: Select fresh roots of Radix Radix Radix Acanthus Radix, after cleaning, dry them in a vacuum drying oven at 60°C for 10 hours, and crush the raw materials of Radix Radix Radix Radix Radix Radix L. after fully drying to 50 meshes;

[0056] a2: Add petroleum ether to the Wujiashen powder obtained in step a1, the mass volume ratio of the Wujiashen powder to petroleum ether is 1g:5mL, reflux and extract for 2 hours, filter and remove the filtrate, and put the filter residue at 50°C for vacuum drying Dry in the box for 30 minutes to volatilize the solvent, and obtain the defatted Wujiaginseng powder from which the fat-soluble impurities in the chlorophyll have been removed;

[0057] Step b, high-pressure extraction of total eleutherosides in defatted Radix Acanthopanax ginseng powder:

[0058] b1: Add 40% ethanol ...

Embodiment 3

[0071] A method for extracting eleutherosides from Acanthopanax ginseng, the steps are as follows:

[0072] Step a, five ginseng raw material pretreatment:

[0073] a1: Select fresh stems of Radix Radix Radix, clean and dry them in a vacuum drying oven at 62°C for 12 hours, and crush the raw materials of Radix Radix Radix to 80 meshes after fully drying;

[0074] a2: Add petroleum ether to the Wujiashen powder obtained in step a1, the mass volume ratio of the Wujiashen powder to petroleum ether is 1g:6mL, filter and remove the filtrate after reflux extraction for 3 hours, and put the filter residue at 50°C for vacuum drying Dry in the box for 30 minutes to volatilize the solvent, and obtain the defatted Wujiaginseng powder from which the fat-soluble impurities in the chlorophyll have been removed;

[0075] Step b, high-pressure extraction of total eleutherosides in defatted Radix Acanthopanax ginseng powder:

[0076] b1: Add 40% ethanol solution to the degreased Acanthopanax...

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Abstract

The invention belongs to the field of extraction and application of plant components, and particularly relates to oral liquid containing radix acanthopanacis senticosi and a method for extracting eleutherosides from the radix acanthopanacis senticosi. According to the invention, the eleutherosides in the radix acanthopanacis senticosi is extracted by a high-pressure extraction process; the eleutherosides are further purified by a polyamide resin and macroporous adsorption resin separation and purification process. The oral liquid containing radix acanthopanacis senticosi provided by the invention only contains drug components with enhanced anti-fatigue ability, has a high content of effective active components and fewer impurities, avoids potential sensitization risks in traditional Chinese medicine drink and burdens and damages caused by complicated drug components to liver and kidney of a user, and can be used for preparing more targeted efficient low-toxic healthcare drink; and theanti-fatigue ability of the user is more comprehensively enhanced by compatibility of various drug polysaccharides in the healthcare drink.

Description

technical field [0001] The invention belongs to the field of extraction and application of plant components, in particular to a method for extracting total eleutherosides from Wujiashen oral liquid and Wujiashen. Background technique [0002] Acanthopanax, also known as Siberian ginseng, Acanthopanax, etc., is a plant of the genus Araliaceae, and is a traditional precious medicinal plant in my country. It is mainly distributed in Heilongjiang, Jilin, Liaoning, Hebei and other places in China. Acanthopanax ginseng tastes pungent, slightly bitter, warm in nature, and non-toxic. It has the effects of nourishing qi and invigorating the spleen, nourishing the kidney and calming the nerves, and strengthening the bones. Using five ginseng to treat coronary heart disease can effectively relieve angina pectoris, and it also has the function of regulating blood pressure. In addition, five ginseng can also be used for leukopenia, diabetes, sexual dysfunction and other diseases; in the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/254A61K9/08A61P39/00A61K127/00A61K133/00A61K131/00A61K135/00A61K125/00A61K31/7032A61K31/704A61K31/715
CPCA61K9/0095A61K31/7032A61K31/704A61K31/715A61K36/254A61K2236/13A61K2236/15A61K2236/17A61K2236/333A61K2236/35A61K2236/37A61K2236/51A61K2236/53A61K2236/55A61K2300/00
Inventor 黄仕研黄诗曼黄樱环
Owner 国草(大连)生物科技有限公司
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