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Traditional Chinese medicine composition for treating nerve headache and preparation method and application thereof

A neurological and composition technology, which is applied in the field of traditional Chinese medicine composition and its preparation for the treatment of neurological headaches, and can solve the problems of lack of chemical medicines and traditional Chinese medicines, etc.

Inactive Publication Date: 2018-06-22
HEILONGJIANG UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, there is still a lack of chemical drugs and traditional Chinese medicines that are ideal for neuropathic headache and have good therapeutic effect and safety.

Method used

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  • Traditional Chinese medicine composition for treating nerve headache and preparation method and application thereof
  • Traditional Chinese medicine composition for treating nerve headache and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Example 1 Chinese medicine granules for treating nervous headache and preparation thereof

[0042] Granule formulation:

[0043]

[0044] Preparation:

[0045] (1) Take the prescribed amount of Cimicifuga, Chuanxiong, Jiushao, Rehmannia, Bupleurum, Chrysanthemum, Salvia, Yuanhu, Vitex, and Puerariae, respectively, and mix them through a 50-mesh sieve, add water 7 times the total mass of Chinese medicinal materials, After soaking for 1 hour, heat and decoct for 4.5 hours, and collect the filtrate by filtration;

[0046] (2) Take the dregs obtained by filtering in step (1), add water three times the total mass of Chinese herbal medicines, decoct for 2 hours, and collect the filtrate by filtration;

[0047] (3) Combine the filtrate obtained in steps (1) and (2), and concentrate it into an extract with a relative density of 1.25;

[0048] (4) Take the extract obtained in step (3) and let it stand at room temperature, add ethanol with a concentration of 95% while stirr...

Embodiment 2

[0054] Example 2 Research on the Antineuropathic Headache Effect of the Pharmaceutical Composition

[0055] 1. Experimental drugs and their preparation

[0056] In this study, 3 groups of comparative drugs and 3 groups of experimental drugs were prepared:

experiment example 1

[0073] Experimental example 1: the thick paste prepared by recipe 1 in Example 1.

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PUM

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Abstract

The invention belongs to the field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating a nerve headache and a preparation method and application thereof. The traditional Chinese medicine composition for treating the nerve headache is prepared from cimicifugae foetidae, Ligusticum wallichii, Paeonia lactiflora, radix rehmanniae preparata, radix bupleuri, chrysanthemum, the root of red-rooted salvia, rhizoma corydalis, Vitex trifolia, the root of kudzu vine and poison bulb, wherein cimicifugae foetidae, Ligusticum wallichii, Paeonia lactiflora, radix rehmanniae preparata, radix bupleuri, chrysanthemum, the root of red-rooted salvia, rhizoma corydalis, Vitex trifolia and the root of kudzu vine are extracted through a water extraction alcohol precipitation method, and poison bulb is used for extracting a volatile oil component with the relative density being 1.0 or below by adopting a water vapor distillation method. The preparation is oral granules preferentially. The composition has the remarkable improvement effect for haematological indexes and behavioral characteristics of a nerve headache animal model, and the safety is good.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating nervous headache, a preparation method and application thereof. Background technique [0002] Nervous headache is a common clinical multiple disease, accounting for about 76% of headache patients. The etiology of the disease is complex, and the exact mechanism is unclear. It is mostly caused by mental stress, anger, irregular life, excessive smoking and alcohol, lack of sleep, mental depression, and endocrine disorders. Among them, nervous headaches caused by vascular dysfunction are the most common. Changes in the natural environment, social environment, and the patient's own living habits and psychological temperament may cause nervous headaches. Due to its complex etiology and unclear mechanism, it is difficult to cure when chemical drugs are used, the condition is easy to repeat, and the course o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P25/00A61P29/00
CPCA61K36/233A61K36/236A61K36/287A61K36/488A61K36/537A61K36/65A61K36/66A61K36/71A61K36/804A61K36/85A61K36/88A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 宁式颖张洪财郭宏伟张浩杨玉赫宁铁桥张博惠文佳郑璐
Owner HEILONGJIANG UNIV OF CHINESE MEDICINE
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