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Pig intramuscular injection compound anesthetic and preparation method thereof

A technology of intramuscular injection and anesthetics, applied in anesthetics, drug combinations, pharmaceutical formulas, etc., can solve the problems of a single drug and difficulty in achieving anesthesia effects, and achieve the effects of small side effects, reliable anesthesia effects, and convenient administration

Inactive Publication Date: 2018-06-22
NORTHEAST AGRICULTURAL UNIVERSITY
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] In order to achieve the above object, the present invention provides a compound anesthetic for pig intramuscular injection and a preparation method thereof, which solves the problem in the prior art that the drug is single and it is difficult to achieve an anesthesia effect

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  • Pig intramuscular injection compound anesthetic and preparation method thereof
  • Pig intramuscular injection compound anesthetic and preparation method thereof
  • Pig intramuscular injection compound anesthetic and preparation method thereof

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Embodiment Construction

[0017] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0018] A compound anesthetic for pig intramuscular injection and a preparation method thereof according to the present invention are composed of component A: 2,4-xylidine thiazole, component B: midazolam, and component C: ketamine hydrochloride. The component content is: per 100mL of water, the mass ratio of component A:B:C is 0.5:0.6:10. The preparation method is to measure 50ml of distilled water with a 100ml graduated cylinder, adjust the pH value to 5.5 wi...

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Abstract

The invention discloses a pig intramuscular injection compound anesthetic and a preparation method thereof, and belongs to the field of veterinarian medicine. The anesthetic is prepared from a component A 2,4-dimethaniline thiazole, a component B midazolam, and a component C ketamine hydrochloride. In 100 mL of water, the mass ratio of the component A to the component B to the component C is 0.5:0.6:10; the preparation method comprises the steps that a 100 ml measuring cylinder is used for measuring 50 ml of distilled water, 1N hydrochloric acid is used for adjusting the PH value to 5.5, then,0.5 g of 2,4-dimethaniline thiazole, 10 g of ketamine hydrochloride and 0.6 g of midazolam are accurately weighed, poured in to be dissolved and mixed to be uniform, the distilled water is added to reach the constant volume being 100 ml, a degerming filter membrane is used for filtering, and subpackaging is performed to obtain the pig intramuscular injection compound anesthetic. The pig intramuscular injection compound anesthetic has the advantages of being real in anesthetic effect, proper in maintenance time and small in side effect, facilitating dosage and the like.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicine, and in particular relates to a composite anesthetic for pig intramuscular injection and a preparation method thereof. Background technique [0002] At present, in the clinical research of human medicine, pigs are used as model animals for the pathogenesis and treatment methods of various diseases, because the homology of pigs is similar to that of humans, such as the current cardiovascular disease, organ transplantation, kidney disease and The clinical application experiments of various drugs, etc., all choose Bama miniature pigs as research objects. Anesthesia of animals is an essential part in the study of various diseases. [0003] At present, there are three methods of anesthesia: inhalation anesthesia, intravenous anesthesia and intramuscular injection anesthesia. Inhalation anesthesia is rarely used in clinical general animal hospitals because of expensive equipment, high drug ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/5517A61K31/137A61K31/426A61P23/00
CPCA61K31/137A61K31/426A61K31/5517A61K2300/00
Inventor 高利陈洪岩肖建华刘怀然李昌文张建涛魏成威李新刘涛姜岩
Owner NORTHEAST AGRICULTURAL UNIVERSITY
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