A Breeding Method for Simplified Selection of High-performance A2A2 Homozygous Genotype Dairy Cows Based on Pedigree Information

Abstract

A pedigree information simplification-based breeding method for selecting high-production performance A2A2 homozygous genotype dairy cattle: by means of determining dairy cattle production performance, collecting individual pedigree data and phenotype data of dairy cattle, and combining a paternal β casein genotype result, carrying out genetic assessment to obtain the breeding values of milk yield, milk fat yield, milk protein yield, and milk protein percentage; by means of calculating an individual high productivity index (HPI) and analyzing the same, obtaining a high-production A2A2 homozygous individual. The workload of the actual production process on a cattle farm is greatly reduced by means of applying large-group screening of daily DHI data; the breeding method may quickly, simply and accurately screen out A2A2 homozygous individuals among a herd of cattle.

Description

technical field [0001] The invention belongs to the technical field of dairy cow breeding, and in particular relates to a breeding method for simplified selection of high-production-performance A2A2 homozygous genotype dairy cows based on pedigree information. Background technique [0002] The protein in milk is the main material basis for the quality of milk, mainly casein and whey protein. Casein accounts for about 80% of milk protein, including four types: alpha s1, alpha s2, beta, and kappa. Beta (β) casein accounts for about 30% of the total protein. Studies have reported that β-casein has 13 types, including A1, A2, A3, A4, B, C, D, E, F, H1, H2, I, and G. Type A1 and A2 β-casein are the two most common types in dairy cow populations. The difference lies in a base change in the β-casein gene, which results in the amino acid at the corresponding position changing from proline to histidine. It is precisely because of the above-mentioned change of an amino acid that th...

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Problems solved by technology

[0003] Molecular genetic breeding is an effective means of dairy cow breeding. By detecting different variant types of β-casein, A2-type bulls and cows can be screened out, and A2 homozygous cows can be cultivated, such as CN105925717A, CN107287292A, CN105219839A , CN105018582A, and CN105018581A disclose detection methods and corresponding kits for distinguishing different variant types of β-casein, which provide effective means for the breeding of A2 homozygous dairy cows. It is too large, or further operations such as breeding and breeding are required, and it is often impossible to take into account the high-yielding performance of dairy cows. Therefore, it is of great production and economic significance to invent a simplified and effective breeding method for high-yielding A2 dairy cows

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