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Composition to prevent and treat hair loss

The technology of a composition and an anti-hair loss agent, which is applied in the directions of drug combination, hair care, medical preparation containing active ingredients, etc., can solve the problems of defective use effect, unreasonable formula, low cost performance, etc., and can prevent hair loss and reduce oxidation. Damage and hair loss prevention effect

Inactive Publication Date: 2018-05-25
聚吉减肥塑形科学技术研究院(广州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

On the other hand, infection by various pathogens such as bacteria, viruses, fungi, spirochetes, parasites, etc. can also lead to severe hair loss
[0003] In order to prevent hair loss, people have developed various hair growth formula products, but most of them have defects in the use effect, and the formula is unreasonable, resulting in low cost performance of the product, and the effective anti-hair loss products also have broad market prospects

Method used

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  • Composition to prevent and treat hair loss
  • Composition to prevent and treat hair loss

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Preparation of anti-hair loss composition:

[0031] Put 4 grams of sclerosin, 7 grams of red ginseng rhizome extract, 0.003 grams of dihydrosphingosine, 4 grams of matrine and 84.997 grams of deionized water in a mixer, stir and mix evenly to obtain the described anti-hair loss composition.

Embodiment 2

[0033] Evaluation test for the effect of inhibiting 5α-reductase activity

[0034] By evaluating the inhibitory effect of the anti-hair loss composition on the activity of 5α-reductase, the inhibition level of the anti-hair loss composition on the synthesis of dihydrotestosterone (abbreviated as DHT) can be determined, thereby determining its anti-hair loss effect. The evaluation method is as follows:

[0035] Blank test group (5α-reductase, dependent reducing coenzyme (NADPH), Tris buffer solution).

[0036] Blank control group (serial concentrations of testosterone, 5α-reductase, dependent reduced coenzyme (NADPH), Tris buffer solution).

[0037] Finasteride group (finasteride solution, testosterone at serial concentrations, 5α-reductase, dependent reducing coenzyme (NADPH), Tris buffer solution).

[0038] Composition group for preventing and treating hair loss (composition for preventing and treating hair loss, testosterone with serial concentrations, 5α-reductase, depend...

Embodiment 3

[0045] Evaluation test on the effect of prevention and treatment of hair loss

[0046] Taking the anti-hair loss composition prepared in Example 1 as a trial sample, 50 cases of seborrheic alopecia patients aged 20-45 were selected, including 40 males and 10 females, as the trial population.

[0047] Treatment method: The patient will gently rub the trial sample on the affected area with a cotton pad, and gently tap the drug-applied area with fingers for 5 minutes, once a day in the morning and evening, 30 days as a course of treatment, and 4 courses of continuous treatment. All patients were followed up and recorded before and after treatment, and the curative effect was evaluated after drug withdrawal.

[0048] Efficacy criteria: recovery (hair loss returned to normal, no itching); marked effect (hair loss was significantly reduced or returned to normal, dandruff and itching disappeared, new hair growth was evident in the affected area or the original fine hair became thicke...

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PUM

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Abstract

The invention discloses a composition to prevent and treat hair loss, comprising Chinese herb 5-alpha reductase inhibitor, an antibacterial agent and a hair loss preventive, wherein the Chinese herb 5-alpha reductase inhibitor includes one or more of nutmeg extract, biochanin, root extract of red ginseng, and Cuscuta reflexa extract. After being applied to cosmetics, the composition enables the scalp to be healthier and effectively prevents and treats hair loss through the route of inhibiting and killing bacteria, inhibiting 5-alpha reductase and promoting hair growth.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to a composition for preventing and treating hair loss. Background technique [0002] Male pattern hair loss is the most common hair loss phenomenon in adult men. The main causes of male pattern hair loss are genetic factors and androgen metabolism disorders. The latter is mainly manifested in the enhanced activity of 5α-reductase, which causes excessive conversion of testosterone into dihydrotestosterone, which accumulates in large quantities in the hair follicles of the scalp, resulting in hair loss. The growth cycle is shortened, the hair follicles degenerate and become smaller, and the hair becomes thinner, softer, shorter, and falls off. On the other hand, infection by various pathogens such as bacteria, viruses, fungi, spirochetes, and parasites can also lead to severe hair loss. [0003] In order to prevent and treat hair loss, people have developed various hair growth formula prod...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/49A61K8/34A61K8/41A61Q7/00A61P17/14
CPCA61K8/347A61K8/41A61K8/4926A61K8/498A61K8/97A61K2800/592A61K2800/782A61Q7/00
Inventor 不公告发明人
Owner 聚吉减肥塑形科学技术研究院(广州)有限公司
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