Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Dendritic polymer-modified magnetic microspheres with uniform particle sizes and preparation method and application thereof

A technology of magnetic microspheres and polymers, applied in the field of functional materials, can solve the problems of uneven particle size, time-consuming, and many steps, and achieve good dispersion and stability, great application prospects, and uniform particle size.

Active Publication Date: 2018-05-18
JIANGSU ACAD OF AGRI SCI
View PDF7 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation method of dendrimer-modified magnetic microspheres has been reported [CN101955231B, CN103157447B], but the post-modification method is usually adopted, which has many steps and takes a long time
[0004] CN102092795A reports a method for preparing organic polymer modified iron ferric oxide multistage balls, but due to its uneven particle size, its performance will be affected in specific applications, such as poor reproducibility, etc.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Dendritic polymer-modified magnetic microspheres with uniform particle sizes and preparation method and application thereof
  • Dendritic polymer-modified magnetic microspheres with uniform particle sizes and preparation method and application thereof
  • Dendritic polymer-modified magnetic microspheres with uniform particle sizes and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0035] The present invention also provides a preparation method of dendritic polymer modified magnetic microspheres with uniform particle size, the method comprising the following steps: S100, preparing a solution for synthesizing magnetic microspheres; S200, uniformly dispersing the dendritic polymer In the solution for synthesizing magnetic microspheres; S300, synthesizing the mixed solution obtained in step S200 into dendrimer-modified magnetic microspheres by a one-pot hydrothermal synthesis method. Such as figure 1 The transmission electron micrograph of the magnetic ferric oxide microspheres modified by the fourth generation of PAMAM dendrimers; as image 3 The fourth generation of PAMAM dendrimer modified magnetic iron ferric oxide microspheres modified boric acid to the extraction amount of adenosine ( image 3 Middle 3), and background literature Chem.Eur.J.2006,12,6341. The extraction amount of adenosine ( image 3 Middle 1), background literature CN103157447B post...

Embodiment 1

[0043] Embodiment 1: Obtained ferroferric oxide magnetic microspheres according to the following preparation method:

[0044] 1.0 parts by weight of ferric chloride hexahydrate, 2.0 parts by weight of anhydrous sodium acetate, and 1 part by weight of the fourth-generation PAMAM dendrimers are successively dissolved in 35.0 parts by weight of ethylene glycol solution, mixed uniformly, and transferred to hydrothermal Reactor, the hydrothermal reaction temperature is 200°C. The reaction time was 6 hours. The prepared magnetic microspheres are washed 3-5 times with methanol, 3-5 times with ethanol, 3-5 times with water and 3-5 times with ethanol. Vacuum dry at 50°C for 12 hours for later use.

[0045] Such as figure 1 as shown, figure 1 It is a transmission electron micrograph of the fourth-generation PAMAM dendrimer-modified magnetic ferric oxide microspheres. It can be seen from the figure that its particle size is uniform, about 100nm.

[0046] figure 2 Infrared image of m...

Embodiment 2

[0047] Embodiment 2: Preparation of cobalt oxide magnetic microspheres:

[0048] 2.0 parts by weight of cobalt chloride hexahydrate, 10 parts by weight of anhydrous sodium acetate, and 2 parts by weight of dendrimers are successively dissolved in 45 parts by weight of ethylene glycol solution, mixed uniformly, transferred to a hydrothermal reaction kettle, and hydrothermally The reaction temperature is 300°C. The reaction time was 8 hours. The prepared magnetic microspheres are washed 3-5 times with methanol, 3-5 times with ethanol, 3-5 times with water and 3-5 times with ethanol. Vacuum dry at 50°C for 12 hours for later use.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle diameteraaaaaaaaaa
Login to View More

Abstract

The invention relates to dendritic polymer-modified magnetic microspheres with uniform particle sizes and a preparation method and application thereof. Through use of a dendritic polymer on the surface of a magnetic carrier, the magnetic microsphere is obtained. The magnetic carrier is a magnetic nanoparticle or a magnetic microparticle. The preparation method comprises directly dispersing the dendritic polymers in a solution for synthesis magnetic microspheres and directly synthesizing the dendritic polymer-modified magnetic microspheres through a hydrothermal synthesis one-pot method. The magnetic microspheres have the better capability of enrichment, have uniform magnetic particle sizes, are prepared through simple processes and are free of post-modification.

Description

technical field [0001] The invention relates to the field of functionalized materials, in particular to a dendrimer-modified magnetic microsphere with uniform particle size and a preparation method and application thereof. Background technique [0002] Magnetic microspheres include magnetic nanoparticles and microparticles. Due to their special physical and chemical properties, they have broad application prospects in the fields of materials and biology, such as magnetic separation and magnetically targeted delivery of drugs. In order to adapt to different purposes, a variety of modified magnetic microspheres and their composite structures, such as functionalized silicon-coated magnetic microspheres, polymer grafted magnetic microspheres and other materials have been widely prepared. And get practical application. Generally, the prepared functionalized magnetic microspheres have a low surface group content and need to be detected and characterized by highly sensitive detect...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): B01J13/06
CPCB01J13/06
Inventor 王合叶王冉
Owner JIANGSU ACAD OF AGRI SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com