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Traditional Chinese medicine composition strengthening immunity and adjusting organism acid-base balance and preparation method thereof

A technology for enhancing immunity and composition, which is applied in the field of traditional Chinese medicine composition and preparation for enhancing immunity and regulating the body's acid-base balance. Fast, Immunity-enhancing or physical fitness, Function-enhancing effects

Inactive Publication Date: 2018-05-18
GUIZHOU MIAOSHI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the above-mentioned immune enhancers are biological products, which are relatively expensive, and some of them require repeated injections to maintain long-term efficacy
In addition, if the legitimate source of blood products cannot be ensured, there is a risk of being easily infected with infectious diseases such as hepatitis

Method used

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  • Traditional Chinese medicine composition strengthening immunity and adjusting organism acid-base balance and preparation method thereof
  • Traditional Chinese medicine composition strengthening immunity and adjusting organism acid-base balance and preparation method thereof
  • Traditional Chinese medicine composition strengthening immunity and adjusting organism acid-base balance and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Example 1 Preparation of Chinese medicinal composition for enhancing immunity and regulating acid-base balance

[0020] (1) Raw materials

[0021] 417g of Ganoderma lucidum, 958.3g of Snake-toothed grape leaves; made into 1000 bags, 3g / bag.

[0022] (2) Preparation process

[0023] Take by weighing 958.3g of Snake-toothed grape leaves and pulverize, cross 80 mesh sieves, irradiate (4kGy) for sterilization, and obtain the sterilized Snake-toothed-toothed grape leaves powder;

[0024] The above 417g ganoderma lucidum was prepared into 41.7g ganoderma lucidum extract by water extraction, and the ganoderma lucidum extract was pulverized through an 80-mesh sieve to obtain ganoderma lucidum powder;

[0025] The water extraction method is specifically: add water and soak for 2h, extract 2 times; extract for the first time and add 10 times of water (10 times of raw material quality) to extract for 1.5h, filter; extract for the second time and add 8 times of water (10 times of...

Embodiment 2

[0030] Embodiment 2, toxicology safety evaluation test

[0031] Sample: the pharmaceutical composition prepared according to the method described in Example 1, specification: 3g / bag, product batch number: 20150507, submitted for inspection, and the inspection unit is Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention (Guangxi Zhuang Autonomous Region Health Monitoring and Inspection Center) . Store samples in a cool dry place. The recommended dosage for human oral administration is 2 times a day per person (adult), 1 bag each time, the adult body weight is calculated as 60kg, and the equivalent dose is 100mg / kg BW. Sample processing method: Weigh 500g of the sample submitted for inspection, add 5000mL of 85°C pure water to soak for 30 minutes, filter the soaking solution with gauze; repeat soaking and extraction once in the same way. Then the two filtrates were combined, and concentrated to 500mL under reduced pressure with a rotary evaporator to obta...

Embodiment 3

[0124] Embodiment 3, enhancing immunity function experiment

[0125] Sample: The pharmaceutical composition prepared according to the method described in Example 1, specification: 3g / bag, product batch number: 20150507, and stored in a cool and dry place. The recommended dosage for human oral administration is 2 times a day per person (adult), 1 bag each time, and the adult body weight is calculated as 60kg, and the equivalent dose is 100mg / kgBW. Sample processing method: Weigh 500g of the sample submitted for inspection, add 5000mL of 85°C pure water to soak for 30 minutes, filter the soaking solution with gauze; repeat soaking and extraction once in the same way. Then the two filtrates were combined, and concentrated to 500mL under reduced pressure with a rotary evaporator to obtain a sample extraction concentrate of 1.0g / mL (calculated as dry product, the same below), which was stored in a refrigerator and prepared with pure water before use. test solution. According to t...

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Abstract

The invention provides a traditional Chinese medicine composition strengthening the immunity and adjusting the organism acid-base balance and a preparation method thereof. The pharmaceutical composition is prepared from ganoderma lucidum and ampelopsis grossedentata. Compared with the prior art, the formula takes the traditional Chinese medicine theory and modern pharmacology research results as the basis, an advanced preparation technology is adopted, and the effect of strengthening the immunity of the product is very definite; the raw materials of the formula come from natural plants, the synergistic effect can be achieved, and the function can be enhanced; the formula can reduce irritation of the medicines; the traditional Chinese medicine composition is rapid in dispersion, good in absorption and high in bioavailability in gastrointestinal fluid; according to the preparation technology, the stability of the medicine can be improved, and convenience is brought to use and transportation. Therefore, the traditional Chinese medicine composition has the advantages of being safe, effective, convenient and the like.

Description

technical field [0001] The application belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition and a preparation method for enhancing immunity and regulating body acid-base balance. Background technique [0002] For tumor patients receiving radiotherapy and chemotherapy, the tumor itself or radiotherapy and chemotherapy can cause acid-base balance imbalance, low immune function, destruction of skin and mucous membrane barrier, decreased defense function of phagocytes, and low cellular and humoral immune function. The chance of infection increases, so infection becomes one of the main causes of death of cancer patients. Immunodeficiency patients, such as AIDS patients, have acid-base balance imbalance and severely impaired immune function, which can easily lead to severe lung or systemic infections. Splenectomy patients are prone to respiratory tract infection and sepsis due to decreased antibody levels an...

Claims

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Application Information

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IPC IPC(8): A61K36/87A61P37/04A61P3/12
CPCA61K36/074A61K36/87A61K2300/00
Inventor 崔宁李蓓蓓李忻
Owner GUIZHOU MIAOSHI PHARMA
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