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Antitumor external-applied plaster composition

A technology for external application of drug patches and compositions, applied in the directions of antitumor drugs, drug combinations, and pharmaceutical formulations, can solve the problems of common radiotherapy and chemotherapy, such as large side effects, patient harm, and high cost of targeted drugs, and achieves improvement of self-immunity, The effect of changing uncomfortable symptoms and reducing the toxic and side effects of radiotherapy

Inactive Publication Date: 2018-05-04
QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the latest anti-tumor drugs developed at home and abroad have made continuous progress, especially the development of targeted drugs, targeted drugs are expensive, common radiotherapy and chemotherapy have large side effects, and clinical overtreatment also brings harm to patients.

Method used

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  • Antitumor external-applied plaster composition
  • Antitumor external-applied plaster composition
  • Antitumor external-applied plaster composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] The raw materials in the anti-tumor traditional Chinese medicine external application composition described in this embodiment are composed by weight: 6 centipedes, 9 g scorpions, 12 g silkworms, 9 g polyphylla, 6 g leeches, 15 g xanthum, 12 g ginseng, 15 g astragalus, and Atractylodes macrocephala. 6g, Poria cocos 3g, deer horn glue 15g, tortoise shell glue 9g, white peony root 6g, wolfberry 9g, rehmannia glutinosa 9g, chuanxiong 6g, purple river carnation 18g, knotweed 12g, geranium seed 12g, ghost needle grass 12g, quartz 12g, atractylodes 6g, Toad venom 12g, honeycomb 24g, hippocampus 9g, citrus aurantium 6g, turtle shell 9g, musk 9g, dayun 9g, bamboo ling 12g, strychnium 50g, ebony plum 9g, crab shell 9g, Yuanhu 12g, clematis 12g, 15g of roasted rice husks, 15g of iron tree leaves, and 9g of Hedyotis diffusa; wherein, the silkworm is a hot product after frying; it puts fresh and alive silkworms in a ceramic pot at 150-200°C and stir-fries them for 20-20°C. 30 minut...

Embodiment 2

[0018] This example uses the composition patch prepared in Example 1 to observe the tumor patients in a center of integrated traditional Chinese and Western medicine, and finds that the effect is remarkable. Use the externally applied patch described in this example on the acupuncture points, and treat it once every three days. The time is a course of treatment, and after a course of treatment, the physical fitness is re-evaluated, and the curative effect judgment standard adopts comprehensive curative effect evaluation, referring to the "Guiding Principles for Clinical Research of New Drugs of Traditional Chinese Medicine" issued by the National Health and Family Planning Commission. The specific curative effect judgment standards are as follows:

[0019] Recovery: All clinical symptoms disappear, laboratory tests are normal, and no recurrence is found within six months after recovery; the transformation score of physical fitness assessment is less than 30 points, and the trans...

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and relates to an antitumor medicine composition adopting Chinese herbal medicines as raw materials. The composition is prepared from the raw materials: centipede, scorpion, stiff silkworm, rhizoma paridis, leech, dioscorea bulbifera, radix ginseng, radix astragali seu hedysari, rhizoma atractylodis macrocephalae, poriacocos, antler gelatin, tortoise-plastron glue, radix paeoniae alba, fructus lycii, radix rehmanniae, rhizoma chuanxiong, human placenta, rhizoma polygoni cuspidate and the like. The selected traditional Chinese medicines are ground into medicine powder with 20 to 30 meshes, and the medicine powder is mixed with a heating element to prepare into an external-applied plaster, wherein the heating element contains ferric chloride, ferrous powder and hydrochloric acid; when the external-applied plaster is used, the composition in the external-applied plaster automatically heats when encountering air, so that the contained volatility compositions are continuously penetrated from the plaster, 'medicine fogs' with temperature and humidity at 45 to 60 DEG C are formed in major points and matching acupoints and directly reach to the acupoints under the action of a heating force so as to be quickly permeated into main and collateral channels, and medicine absorption is promoted; the composition can be suitable for a wide patient population range, is beneficial to easing patient pains and reducing a radiotherapy and chemotherapy toxic and side effects, has an enhancement effect on improving the immunity and the living quality of malignant tumor patients, and is friendly to an application environment.d the living quality of malignant tumor patients, and is friendly to an application environment.

Description

Technical field: [0001] The invention belongs to the technical field of traditional Chinese medicines, and relates to an anti-tumor pharmaceutical composition using Chinese herbal medicines as raw materials, in particular to an anti-tumor externally applied medicinal patch using Chinese herbal medicines as raw materials and its preparation process and application method. Background technique: [0002] Tumor is one of the common diseases that threaten human health, second only to cardiovascular and cerebrovascular diseases, and is recognized as one of the most difficult diseases in the medical field today, with a high incidence rate and great harm to human life and health. At present, the methods of clinical treatment of malignant tumors are usually surgery, radiotherapy and chemotherapy. While killing cancer cells, many normal cells of the human body are also eliminated, which brings great pain and psychological pressure to patients. Among them, surgery and radiotherapy are a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/70A61P35/00A61F7/03A61K33/00A61K35/32A61K35/50A61K35/55A61K35/586A61K35/60A61K35/612A61K35/62A61K35/64A61K35/646A61K35/648A61K35/65
CPCA61K36/8945A61K36/896A61F7/034A61K9/70A61K33/00A61K35/32A61K35/50A61K35/55A61K35/586A61K35/60A61K35/612A61K35/62A61K35/63A61K35/646A61K35/648A61K35/65A61K36/07A61K36/076A61K36/13A61K36/236A61K36/258A61K36/28A61K36/284A61K36/481A61K36/56A61K36/64A61K36/65A61K36/66A61K36/704A61K36/71A61K36/716A61K36/736A61K36/748A61K36/752A61K36/804A61K36/815A61K36/88A61K2300/00
Inventor 倪同上黄彩娜胡瑞鹏王宏韬葛科立刘天蔚郭云良
Owner QINGDAO UNIV
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