A method for three-dimensional printing artificial skin

Abstract

The present invention discloses a method for three dimensional printing artificial skin. The method comprises the following steps of: printing a dermis layer by a hydrogel combined with an autologousdermal cell; printing an epidermis layer on the dermis layer by a hydrogel combined with an autologous kerationocytes cell; and implanting a plurality of progenitor cells for sweat glands and hair follicles through the epidermis layer into the dermis layer to form an artificial skin. Because all used materials are from the autologous skin, and the 3D printing technology is used to implant the progenitor cells for sweat glands and hair follicles to form the artificial skin which has sweat glands and hair follicles. According to the method, an artificial skin with a complete skin structure is completed.

Description

technical field [0001] The present invention relates to a method of preparing artificial skin, and in particular, to a method of 3D printing artificial skin with sweat glands and hair follicles. Background technique [0002] The skin is the largest tissue structure of the human body. It not only has the functions of regulating body temperature and preventing water loss in the human body, but also is the first line of defense for the human body to defend against external pathogens and bacterial infections. So whenever there is extensive damage to the skin, the body is at risk of dehydration and death from bacterial infection. [0003] There are several ways to traditionally treat skin damage that cannot heal naturally: take a piece of skin from another part of the patient's body and put it on the wound; or take skin from other humans or mammals (such as pigs) and put it on the wound . The former cannot obtain a large amount of skin, otherwise it is easy to cause bacterial i...

AI Technical Summary

Problems solved by technology

[0006] However, no matter whether the artificial skin obtained from mammals or the artificial skin shaped by polymer materials cannot obtain the original sweat glands and hair follicles of the skin, the artificial skin loses the functions of perspiration and hair follicle protection

[0007] It can be seen that the above-mentioned conventional technology still has many deficiencies, it is not a good design, and needs to be improved urgently.

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