3D printing method for artificial skin

Abstract

The invention discloses a method for 3D printing artificial skin, which includes the following steps: mixing autologous dermal cells and hydrocolloid material and printing the dermis layer; mixing autologous keratinocytes and hydrocolloid material and printing the epidermis layer on the dermis layer; and combining sweat glands with Hair follicle precursor cells are implanted and printed through the epidermis layer into the dermis layer to produce artificial skin. Because the materials used are separated from autologous skin and combined with 3D printing technology to implant sweat glands and hair follicle precursor cells to obtain an artificial skin with sweat glands and hair follicles, the artificial skin obtained by the method of 3D printing artificial skin of the present invention is fully functional. Skin structure.

Description

technical field [0001] The present invention relates to a method of preparing artificial skin, and in particular, to a method of 3D printing artificial skin with sweat glands and hair follicles. Background technique [0002] The skin is the largest tissue structure of the human body. It not only has the functions of regulating body temperature and preventing water loss in the human body, but also is the first line of defense for the human body to defend against external pathogens and bacterial infections. So whenever there is extensive damage to the skin, the body is at risk of dehydration and death from bacterial infection. [0003] There are several ways to traditionally treat skin damage that cannot heal naturally: take a piece of skin from another part of the patient's body and put it on the wound; or take skin from other humans or mammals (such as pigs) and put it on the wound . The former cannot obtain a large amount of skin, otherwise it is easy to cause bacterial i...

AI Technical Summary

Problems solved by technology

[0006] However, no matter whether the artificial skin obtained from mammals or the artificial skin shaped by polymer materials cannot obtain the original sweat glands and hair follicles of the skin, the artificial skin loses the functions of perspiration and hair follicle protection

[0007] It can be seen that the above-mentioned conventional technology still has many deficiencies, it is not a good design, and needs to be improved urgently.

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