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Toxoplasma gondii repellent pharmaceutical composition, preparation method and uses thereof

A composition, the technology of Toxoplasma gondii, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of large side effects of drugs, incomplete treatment, and inability to prevent them, so as to achieve no toxic side effects, Guarantee the effect of life and study, good health care

Inactive Publication Date: 2018-04-20
宋作华 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, for toxoplasmosis caused by toxoplasma infection, patients can only be treated after diagnosis, and cannot be prevented. If it is discovered or treated in time, the disease will be delayed
In addition, the existing treatment plans for Toxoplasma gondii infection mainly use drugs such as spiramycin, clindamycin, and azithromycin. The side effects of drugs are relatively large, and incomplete treatment often recurs, seriously affecting normal life and study

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A pharmaceutical composition for expelling toxoplasma gondii, which is composed of the following raw materials: 27 grams of Artemisia annua, 47 grams of Turtle Carapace, 11.2 grams of Rehmannia glutinosa, 5.6 grams of Rhizoma Polygonatum, 5.6 grams of Lycium barbarum, and 3.6 grams of Caulis Spatholobus.

[0025] In this embodiment, the preparation method of the pharmaceutical composition for expelling Toxoplasma gondii, the steps are as follows:

[0026] 1) Remove impurities from Artemisia annua, Turtle Shell, Rehmannia glutinosa, Rhizoma Polygonatum, Lycium barbarum and Caulis Spatholobus, and clean them up;

[0027] 2) Weighing 27 grams of Artemisia annua, 47 grams of Turtle Carapace, 11.2 grams of Rehmannia glutinosa, 5.6 grams of Rhizoma Polygonatum, 5.6 grams of Lycium barbarum, and 3.6 grams of Caulis Spatholobus treated in step 1), and mixed to obtain a mixture;

[0028] 3) adding ethanol to the mixture obtained in step 2), soaking, and filtering to obtain a dru...

Embodiment 2

[0032] A pharmaceutical composition for expelling toxoplasma gondii, which is composed of the following raw materials: 26 grams of Artemisia annua, 44.6 grams of Turtle Carapace, 13 grams of Rehmannia glutinosa, 6.5 grams of Rhizoma Polygonatum, 6.5 grams of Lycium barbarum, and 3.4 grams of Caulis Spatholobus.

[0033] In this embodiment, the preparation method of the pharmaceutical composition for expelling Toxoplasma gondii, the steps are as follows:

[0034] 1) Remove impurities from Artemisia annua, Turtle Shell, Rehmannia glutinosa, Rhizoma Polygonatum, Lycium barbarum and Caulis Spatholobus, and clean them up;

[0035] 2) Weighing 26 grams of Artemisia annua, 44.6 grams of Turtle Carapace, 13 grams of Rehmannia glutinosa, 6.5 grams of Rhizoma Polygonatum, 6.5 grams of Lycium barbarum, and 3.4 grams of Miltonia Spatholobus treated in step 1), and mixed to obtain a mixture;

[0036] 3) adding ethanol to the mixture obtained in step 2), soaking, and filtering to obtain a d...

Embodiment 3

[0040] A pharmaceutical composition for expelling toxoplasma gondii, which is composed of the following raw materials: 23 grams of Artemisia annua, 42.3 grams of Turtle Carapace, 15.2 grams of Rehmannia glutinosa, 7.6 grams of Rhizoma Polygonatum, 7.6 grams of Lycium barbarum, and 4.3 grams of Caulis Spatholobus.

[0041] In this embodiment, the preparation method of the pharmaceutical composition for expelling Toxoplasma gondii, the steps are as follows:

[0042] 1) Remove impurities from Artemisia annua, Turtle Shell, Rehmannia glutinosa, Rhizoma Polygonatum, Lycium barbarum and Caulis Spatholobus, and clean them up;

[0043] 2) Weighing 23 grams of Artemisia annua, 42.3 grams of Turtle Carapace, 15.2 grams of Rehmannia glutinosa, 7.6 grams of Rhizoma Polygonatum, 7.6 grams of Lycium barbarum, and 4.3 grams of Miltonia Spatholobus treated in step 1), and mixed to obtain a mixture;

[0044] 3) adding ethanol to the mixture obtained in step 2), soaking, and filtering to obtain...

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PUM

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Abstract

The invention discloses a Toxoplasma gondii repellent pharmaceutical composition, which is prepared from the following raw materials by weight: 23-27% of artemisia annua l, 40-48% of carapax trionycis, 11.2-15.2% of radix rehmanniae preparata, 5.6-7.6% of polygonatum sibiricum, 5.6-7.6% of Chinese wolfberry, and 2.8-4.3% of kadsurae caulis. The invention further discloses a preparation method of the Toxoplasma gondii repellent healthy medicinal wine, wherein the preparation method specifically comprises: respectively removing impurities from various raw materials, cleaning, weighing the cleaned raw materials according to a certain formula amount, mixing to obtain a mixture, adding ethanol to the mixture, soaking, filtering to obtain a drug leaching solution, heating and drying the drug leaching solution by using a high-speed centrifugal spray dryer to obtain powder, and carrying out sealed bagging. According to the present invention, the Toxoplasma gondii repellent pharmaceutical composition can effectively repel Toxoplasma gondii, does not have toxic-side effect, and can avoid the toxoplasmosis caused by Toxoplasma gondii so as to prevent disease.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for expelling toxoplasma gondii and its preparation method and application. Background technique [0002] Toxoplasma gondii is called three corpses in traditional Chinese medicine, which is an intracellular parasite. Parasitic in the cells, with the blood flow, reach all parts of the body, damage the brain, heart, fundus, resulting in a decline in human immunity, suffering from various diseases. It is an obligate intracellular parasite, subclass Coccidia, order Eucoccidia, Isospora Coccidiaceae, Toxoplasma genus. Phytotrophoblasts can secrete penetration-enhancing factors, actively attack to change the cell wall and enter the cell to damage it. The host can develop a certain immunity to it and destroy some of the worms, while some of the worms that have not been eliminated often hide in the brain and eyes and form cysts. When the host's ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P33/02A61K35/586
CPCA61K35/586A61K36/282A61K36/486A61K36/804A61K36/815A61K36/8969A61K2236/333A61K2236/51A61K2236/53A61K2300/00
Inventor 宋作华冯富有
Owner 宋作华
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