Method for preparing 5-hydroxymethyl furfural from glucose

Abstract

The invention discloses a method for preparing 5-hydroxymethyl furfural from glucose. The method comprises the following steps: (1) adding glucose, a solid acid catalyst, a NaCl aqueous solution and ethyl acetate into a high-pressure reaction kettle, and heating to 180-200 DEG C at a stirring speed of 400-600 rpm to react, thereby obtaining a reaction phase and an extraction phase; and (2) separating the reaction phase from the extraction phase obtained in step (1), adding glucose and ethyl acetate into the reaction phase in proportion, and continuously reacting by utilizing the solid acid catalyst in the reaction phase under conditions of the step (1). The method is simple to operate, adopts cheap and easily available raw materials, adopts the green and environment-friendly catalyst, adopts ethyl acetate with a low boiling point as an extraction solvent, so that the separating and purifying of 5-hydroxymethyl furfural from glucose is facilitated, and an industrial value is realized.

Description

technical field [0001] The invention belongs to the technical field of organic synthesis, and in particular relates to a method for preparing 5-hydroxymethylfurfural from glucose. Background technique [0002] 5-Hydroxymethylfurfural is an important biomass-based platform compound. The molecule contains a furan ring, an aldehyde group and a hydroxymethyl group, so it can undergo hydrogenation, oxidative dehydrogenation, esterification, halogenation, polymerization, A variety of high value-added derivatives can be prepared through hydrolysis and other reactions, such as levulinic acid, furandicarboxylic acid, furandimethanol, furandicarbaldehyde and dimethylfuran, which can be used in polymers, biofuels and other fields. 5-Hydroxymethylfurfural is mainly produced by dehydration of glucose and fructose under acidic conditions. Using fructose as raw material can often get higher yield of 5-hydroxymethylfurfural, but using glucose as raw material to prepare 5-hydroxymethylfurfu...

AI Technical Summary

Problems solved by technology

[0003] In the prior art, the catalysts for preparing 5-hydroxymethylfurfural from glucose can be simply divided into homogeneous acid catalysts and solid acid catalysts. Due to the shortcomings of homogeneous acid catalysts such as corrosion equipment, dangerous operation, and difficult recovery, solid acid catalysts has become mainstream

Among many solid acid catalysts, chromium-based solid acid catalysts show good catalytic activity in the process of catalyzing glucose to prepare 5-hydroxymethylfurfural, but chromium-based solid acid catalysts will lose part of the chromium during the reaction. Unfriendly to the environment to a certain extent, contrary to the concept of green chemistry

At the same time, most of the reaction solvents used to prepare 5-hydroxymethylfurfural from glucose are ionic liquids and high-boiling organic solvents, but there are disadvantages such as high price and high energy consumption for separation.

Images