DNA (deoxyribonucleic acid) preservation solution for oral swabs and method for preparing DNA preservation solution

Abstract

The invention discloses DNA (deoxyribonucleic acid) preservation solution for oral swabs. The DNA preservation solution comprises, by weight-to-volume ratio, trihydroxymethyl aminomethane, sodium alginate, tripotassium phosphate, zinc gluconate, ethylene diamine tetraacetic acid disodium, L-carnitine, valine, natural preservatives, vitamin e, normal saline, stevioside, sodium polystyrene sulfonateand sodium dihydrogen phosphate. Deionized water is used as a solvent for the DNA preservation solution. The DNA preservation solution has the advantages that the DNA preservation solution is preservation solution pertinently for the oral swabs, and oral cells can be effectively preserved by the DNA preservation solution; the DNA preservation solution is hygienic, and bacterium breeding can be prevented; the preservation time is longer than 3-5 times the preservation time of envelopes; a method for preparing the DNA preservation solution is simple and has a good social value.

Description

technical field [0001] The invention relates to a DNA preservation solution, in particular to an oral swab DNA preservation solution and a preparation method thereof. Background technique [0002] The oral cell sampling steps include: 1) Tear off the outer packaging of the oral swab, and carefully take out the oral swab (note: hands cannot touch the swab during the entire sampling process). 2) Hold the handle, insert the swab into the left oral cavity, make the swab head fully touch the mucous membrane on the inside of the left cheek / left upper and lower gums, and rub up and down with the strength of brushing teeth. At the same time, rotate the swab to let the swab The child's head fully contacts the oral mucosa, and repeats this action for 1 minute. 3) Use the same method to sample the second swab at the mucosa of the right cheek / right upper and lower gums. 4) Put the swab stained with oral exfoliated cells in a clean and ventilated place for at least one hour until it dr...

AI Technical Summary

Problems solved by technology

However, the storage of oral swabs is generally sealed in a marked envelope, which is not hygienic and prone to bacteria; and the storage time is short