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Medicine for treating ICPP and preparation method of medicine

A technology of medicine and liquid medicine, applied in the field of medicine for treating ICPP and its preparation, can solve the problems of reducing the effect of serum GH level, affecting the normal growth and development of children, and insufficient curative effect, so as to improve the level of psychological toughness and psychological resilience. , to ensure normal growth and development, the effect of great practical value

Inactive Publication Date: 2018-03-23
GUANGZHOU HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] (1) The curative effect of the drugs currently on the market for the treatment of ICPP is not significant enough, and the success rate is low;
[0005] (2) The drugs currently on the market for the treatment of ICPP have relatively large side effects, such as the obvious effect of reducing serum GH levels, which affects the normal growth and development of children

Method used

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  • Medicine for treating ICPP and preparation method of medicine
  • Medicine for treating ICPP and preparation method of medicine

Examples

Experimental program
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Effect test

preparation example Construction

[0037] A preparation method of a medicine for the treatment of ICPP, comprising the steps of:

[0038] Decoction step: add water 8-12 times the weight of the medicinal material to the medicinal material of the formula, soak for 15-45 minutes, and directly decoct for the first time after soaking for 1-3 hours; after the first decoction, the obtained Pour out and collect the first medicinal liquid; add water 7-9 times the weight of the medicinal material to the medicinal material, decoct for the second time, and obtain the second medicinal liquid;

[0039] Filtration concentration step: mixing the first medicinal liquid and the second medicinal liquid to obtain a mixed medicinal liquid, using a 20-40 mesh screen to filter the mixed medicinal liquid to obtain a filtrate, and concentrating the filtrate until the relative water density of the filtrate is 1.02-1.08, get clear ointment;

[0040] Preparation steps: add 2-4 parts by weight of benzoic acid and 0.3-0.7 parts by weight o...

Embodiment 1-5

[0048] A medicine for treating ICPP, the specific components and dosage (parts by weight), more specifically, each part by weight is 1 g in the following Examples 1-5, see Table 1 below.

[0049] The formula table of the medicine of the treatment ICPP of table 1 embodiment 1-5

[0050]

[0051]

Embodiment 6

[0053] A preparation method of a medicine for the treatment of ICPP, comprising the steps of:

[0054] Decoction step: add water 8-12 times the weight of the medicinal material to the medicinal material of the formula, soak for 15-45 minutes, and directly decoct for the first time after soaking for 1-3 hours; after the first decoction, the obtained Pour out and collect the first medicinal liquid; add water 7-9 times the weight of the medicinal material to the medicinal material, decoct for the second time, and obtain the second medicinal liquid;

[0055] Filtration concentration step: mixing the first medicinal liquid and the second medicinal liquid to obtain a mixed medicinal liquid, using a 20-40 mesh screen to filter the mixed medicinal liquid to obtain a filtrate, and concentrating the filtrate until the relative water density of the filtrate is 1.02-1.08, get clear ointment;

[0056] Preparation steps: add 2-4 parts by weight of benzoic acid and 0.3-0.7 parts by weight o...

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PUM

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Abstract

The invention discloses a medicine for treating ICPP and a preparation method thereof. The medicine comprises the following components: anemarrhena, cortex phellodendri, habitat, broiled tortoise shell, dendrobium, alisma, poria cocos, paeonol, achyranthes bidentata and licorice. The drug can effectively improve children's final height, delay menstrual cramps, help improve children's psychological toughness and resilience, and have positive effects on children's long-term psychological behavior and intelligence. The medicine has the advantages of remarkable effect, no toxic side effect and no adverse reaction when treating ICPP.

Description

technical field [0001] The invention relates to a medicine, in particular to a medicine for treating ICPP and a preparation method thereof. Background technique [0002] The main hazard of children with idiopathic central precocious puberty (ICPP) is that the adult height may be short due to the short growth period. The main reason is that puberty starts prematurely, the epiphysis fuses prematurely, and the growth period is shortened, resulting in the patient's adult height being significantly smaller than that of his peers with normal pubertal development, and the occurrence rate of the disease in girls is much higher than that in boys probability of occurrence. [0003] However, the existing drugs for the treatment of ICPP have the following defects: [0004] (1) The curative effect of the drugs currently on the market for the treatment of ICPP is not significant enough, and the success rate is low; [0005] (2) The drugs currently on the market for the treatment of ICP...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61P25/00A61P5/00A61K35/586
CPCA61K36/8964A61K35/586A61K36/076A61K36/21A61K36/484A61K36/65A61K36/71A61K36/756A61K36/804A61K36/884A61K36/8984A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 徐雯王媛媛邱芳华梁基智石艳红
Owner GUANGZHOU HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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