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Chitosan material and preparation method thereof

A technology of chitosan and preparation method, applied in medical science, bandages, etc., can solve the problems of less body fluid adsorption at the wound site, unfavorable wound healing of patients, and difficulty in judging the wound condition, etc., achieving good biocompatibility and low cost , the effect of structural stability

Inactive Publication Date: 2018-03-09
NANJING YIHE CULTURE CREATIVE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the traditional wound covering material is mainly gauze, which has less absorption of body fluids at the wound site and is opaque, it is difficult to judge the condition of the wound and needs to be replaced frequently, which not only increases the pain of the patient, but also increases the probability of wound infection, which is not conducive to patient wound healing

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A chitosan material, mainly composed of chitosan hydrogel, is a transparent material with changeable shapes and a water absorption rate of 1700%.

[0018] A method for preparing chitosan material, comprising the following steps:

[0019] Step 1. configuration concentration is the aqueous solution of 1% chitosan;

[0020] Step 2. Freeze the aqueous solution in step 1 below -10 °C for 8 hours, and then let it stand at room temperature for 10 hours to obtain an elastic jelly-like material.

[0021] Step 3. The material obtained in step 2 is cross-linked and polymerized by means of radiation cross-linking to obtain a chitosan hydrogel wound covering material.

[0022] In the preparation method of a chitosan material composite material, the chitosan described in step 1 is chitosan-200.

[0023] In the method for preparing a chitosan composite material described above, the radiation source described in step 3 is gamma rays of cobalt-60.

[0024] The chitosan material is us...

Embodiment 2

[0026] A chitosan material, mainly composed of chitosan hydrogel, is a transparent material with no fixed shape and a water absorption rate of 1900%.

[0027] A method for preparing chitosan material, comprising the following steps:

[0028] Step 1. configuration concentration is the aqueous solution of the chitosan of 20%;

[0029] Step 2. Freeze the aqueous solution in step 1 at -20 °C for 24 hours, and then let it stand at room temperature for 24 hours to obtain an elastic jelly-like material.

[0030] Step 3. The material obtained in step 2 is cross-linked and polymerized by means of radiation cross-linking to obtain a chitosan hydrogel wound covering material.

[0031] In the preparation method of the above-mentioned chitosan material composite material, the chitosan described in step 1 is chitosan-400.

[0032] In the preparation method of a chitosan material composite material, the radiation source described in step 3 is an electron beam.

[0033] The chitosan materi...

Embodiment 3

[0035] A chitosan material, mainly composed of chitosan hydrogel, is a transparent material with changeable shapes and a water absorption rate of 1700%.

[0036] A method for preparing chitosan material, comprising the following steps:

[0037] Step 1. configuration concentration is the aqueous solution of chitosan of 1-%;

[0038] Step 2. Freeze the aqueous solution in step 1 at -15 °C for 16 hours, and then let it stand at room temperature for 17 hours to obtain an elastic jelly-like material.

[0039] Step 3. The material obtained in step 2 is cross-linked and polymerized by means of radiation cross-linking to obtain a chitosan hydrogel wound covering material.

[0040] In the method for preparing a chitosan composite material described above, the chitosan described in step 1 is chitosan-600.

[0041] In the preparation method of a kind of chitosan material composite material, the radiation source described in step 3 is ultraviolet rays.

[0042] The chitosan material is...

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Abstract

The invention discloses a chitosan material and a preparation method thereof. The chitosan material is mainly composed of chitosan hydrogel, and has extremely high water absorbability. The chitosan material is prepared from a cheap and easily available chitosan reactant through a radiation cross-linking technology. The preparation method has the advantages of simple process, suitableness for industrial mass production, low cost, and basically no environmental protection.

Description

Technical field: [0001] The invention relates to a chitosan material and a preparation method thereof. Background technique: [0002] Chitosan is a kind of water-soluble polymer material. Chitosan hydrogel is a gel-like polymer material with certain water absorption and mechanical strength obtained after chitosan molecules are cross-linked and polymerized. Because of its good biocompatibility, it is widely used in the field of biomedicine. [0003] In clinical medicine, wound dressing materials have always occupied an important position. Because the traditional wound covering material is mainly gauze, which has a small amount of absorption of body fluids at the wound site and is opaque, it is difficult to judge the condition of the wound and needs to be replaced frequently, which not only increases the pain of the patient, but also increases the probability of wound infection, which is not conducive to Patient wound healing. Therefore, it is imperative to develop a new ty...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08J3/28C08J3/24C08J3/075A61L26/00C08L5/08
CPCC08J3/28A61L26/0023A61L26/008C08J3/075C08J3/24C08J2305/08C08L5/08
Inventor 王军红
Owner NANJING YIHE CULTURE CREATIVE CO LTD
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