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A kind of beriberi preparation and preparation method thereof

A kind of preparation and beriberi technology, which is applied in anti-inflammatory agents, medical formulas, antifungal agents, etc. It can solve the problems of corroding the skin, not easy to smear, and no deodorizing effect, so as to inhibit the secretion of sweat glands, keep dry and clean, and eliminate The effect of living environment

Active Publication Date: 2020-06-05
KUNMING BEIJIAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There are many products on the market to treat beriberi. External preparations mainly include traditional Chinese medicine compound preparations with salicylic acid, phenol and other ingredients, and external preparations made of antifungal drugs such as ketoconazole, miconazole, and bitnafine. Adding salicylic acid and phenolic traditional Chinese medicine products are highly irritating and corrosive to the skin; antifungal drug preparations are inconvenient to use, and it is not easy to smear nails and nail grooves; the curative effect on hyperhidrosis and compound beriberi is poor; no deodorant Function, can not be used in shoes and socks, easy to cross infection

Method used

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  • A kind of beriberi preparation and preparation method thereof
  • A kind of beriberi preparation and preparation method thereof
  • A kind of beriberi preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] a. Take 19ml of 95% medical ethanol, then add accurately weighed 0.5g of triclosan, 0.5g of miconazole nitrate, 0.05g of dexamethasone, and 10ml of dimethyl sulfoxide and stir to dissolve to obtain A solution;

[0029] b. Take 19ml of 95% medical ethanol, then add accurately measured 10g of urotropine and 3ml of glycerin and stir to dissolve to obtain solution B;

[0030] c. Stir and mix solution B and solution A, add accurately measured 0.5g of laurocapram, 0.01g of menthol and 0.01g of essence, stir evenly, add deionized water to the full volume of 100ml to obtain beriberi preparation.

Embodiment 2

[0032] a. Take 20ml of 95% medical ethanol, then add accurately weighed 0.75g of triclosan, 1g of miconazole nitrate, 0.06g of dexamethasone, and 12ml of dimethyl sulfoxide and stir to dissolve to obtain A solution;

[0033] b. Take 20ml of 95% medical ethanol, then add accurately measured 12g of urotropine and 5ml of glycerin and stir to dissolve to obtain B solution;

[0034] c. Stir and mix solution B and solution A, add accurately measured 1g of laurocapram, 0.02g of menthol and 0.02g of essence, stir evenly, add deionized water to the full volume of 100ml to obtain beriberi preparation.

Embodiment 3

[0036] a. Take 21ml of 95% medical ethanol, then add accurately weighed 1g of triclosan, 1.5g of miconazole nitrate, 0.075g of dexamethasone, and 15ml of dimethyl sulfoxide and stir to dissolve to obtain A solution;

[0037] b. Take 21ml of 95% medical ethanol, then add accurately measured 15g of urotropine and 7ml of glycerol and stir to dissolve to obtain B solution;

[0038] c. Stir and mix solution B and solution A, add accurately measured 1.5g of laurocapram, 0.03g of menthol and 0.03g of essence, stir evenly, add deionized water to the full volume of 100ml to obtain beriberi preparation.

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Abstract

The invention discloses a dermatophytosis preparation. In the dermatophytosis preparation, miconazole nitrate and triclosan are main bactericidal components and can generate a synergistic effect by matched use to enhance a bactericidal effect; urotropin mainly plays roles in convergence and hidroschesis in a formula and simultaneously has a bactericidal effect; hexadecadrol is a corticosteroid drug and mainly plays anti-inflammatory and anti-pruritic roles in the formula; dimethyl sulfoxide mainly plays a solubilizing role in the formula to dissolve the miconazole nitrate and the hexadecadroland simultaneously has a trans-dermal effect to enhance the trans-dermal absorption of the drug and enhance the drug effect; laurocapram is a trans-dermal absorbing agent to enhance the drug trans-dermal absorption function; glycerol is a moisturizing agent and mainly plays roles in moisturizing skin, reducing irritation and increasing drug adhesion in the formula; medical ethanol is mainly used as a solvent and simultaneously has a bactericidal effect; menthol and essence are taken as flavoring agents to improve the drug odor and improve the use experience; the dermatophytosis preparation simultaneously has the effect of covering the foot odor.

Description

technical field [0001] The invention belongs to the technical field of medicine for external use, and in particular relates to a beriberi preparation and a preparation method thereof. Background technique [0002] Tinea pedis, commonly known as athlete's foot, is caused by fungal infection of the feet. The main symptoms are: itchy skin on the feet, peeling blisters, and erosion and stench. Athlete's foot is caused by fungal infection. After fungal infection, it penetrates into the deep layer of the skin and reproduces parasiticly. In the high temperature of 120 ℃, it will not die within 10 minutes, and it can also maintain its activity for more than one year on the hair, nail (toe) and dander that have been separated from the living body. [0003] Pathogenic fungi, like warm and humid, vigorous growth and reproduction in summer, low nutritional requirements, strong resistance to common disinfectants, antibiotics, etc., so ringworm is ubiquitous in the external environment, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/573A61K31/53A61K31/085A61K31/4174A61P31/02A61P31/10A61P17/00A61P17/04A61P29/00
CPCA61K31/085A61K31/4174A61K31/53A61K31/573A61K2300/00
Inventor 龚泰军
Owner KUNMING BEIJIAN BIOTECH
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