Method for extracting silymarin

Abstract

The invention relates to a method for extracting silymarin. The method is characterized by comprising the following steps: soaking silybum marianum seeds in ethyl acetate for a preset time; taking thesoaked silybum marianum seeds out from the ethyl acetate, adding the soaked silybum marianum seeds into a hulling machine, and shelling the silybum marianum seeds; putting the silybum marianum shellinto an extraction tank of tank group type gradient extraction equipment, and adding ethyl acetate and a diluent into the extraction tank; performing gradient extraction on the silybum marianum shellto obtain a primary extracting solution of silymarin; concentrating the primary extracting solution to obtain a silybum marianum concentrated solution; and adding an alkaline aqueous solution into theconcentrated solution and performing stirring, then performing standing, precipitating and drying, and performing crushing and sieving so as to obtain the silymarin. According to the scheme providedby the invention, a gradient extraction mode is used, so that the extraction rate of the silymarin is increased, and the production energy consumption and the production cost are reduced.

Description

technical field [0001] The embodiments of the present invention relate to a production method, in particular to a production method of silymarin. Background technique [0002] Silymarin is a mixture of flavonoid lignans derived from the seeds of Silybum marianum. Its main components include flavonoids such as silibinin, isosilibinin, dehydrosilibinin, silymarin and silibinin. Silymarin has hepatoprotective and choleretic effects and is mainly used for the treatment of liver diseases. Secondly, it also has obvious anti-lipid peroxidation, anti-radiation, scavenging free radicals, anti-stomach ulcer and other effects. It has good effects in lowering blood lipids, preventing and treating atherosclerosis, preventing cerebral ischemia, and resisting platelet aggregation. Non-toxic, non-teratogenic and mutagenic. [0003] At present, there are two main extraction methods for silymarin, one is organic solvent extraction, and the other is alkali extraction and acid precipitation...

AI Technical Summary

Problems solved by technology

The problem with this method is that after the milk thistle seeds are crushed, the oil cannot be completely extracted, which will have a certain impact on the subsequent extraction purity of silymarin; another technique is to shell the milk thistle seeds first, and then use water Silymarin is extracted from silymarin shells to avoid the influence of oil in milk thistle seeds, but this method needs to be shelled separately, and then the silymarin shells must be softened, soaked and other procedures before silymarin can be extracted, which greatly increases Extraction process, increased extraction time cost and economic cost

Images