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Multispectral optical technology fused temperature measuring device

A temperature measurement device and multi-spectral technology, applied in the field of optical temperature measurement, can solve the problems of high price, low specificity and temperature rise sensitivity, long time, etc., and achieve the effect of improving stability, reducing error and improving accuracy

Pending Publication Date: 2018-02-09
XIAMEN UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Traditional nuclear magnetic resonance detection technology can obtain high-resolution and high-contrast temperature rise images, but it takes a long time and is expensive, and this method is easily affected by tissue electrical conductivity; near-infrared thermal imaging can only obtain superficial tissue temperature Distributed thermal images, but cannot detect deep tissue; Ultrasound scanning technology can provide real-time deep tissue internal temperature rise images, but its contrast and temperature rise sensitivity is low

Method used

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  • Multispectral optical technology fused temperature measuring device
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Embodiment Construction

[0020] like figure 1 As shown, in this embodiment, the multispectral tunable laser 1 is used as the output end of the light source, and the output parallel beam passes through the variable filter 2 to attenuate the energy, and then passes through the beam shaper 4 to shape and expand the beam; then The beam is incident to the beam splitter 4 to split the beam, a part of the light is used as the reference light of the reference arm of the optical coherent microscope module, and a part of the light passes through the focusing lens 7, and then enters the collimated beam expansion through the deep hole diaphragm 8 The lens group 9, after expanding the beam, is incident on the high-speed scanning galvanometer 10, and then through the large-aperture microscopic objective lens 11, the beam is focused and passed through the water tank 14, and the focused spot is irradiated to the sample 12; then the high-precision temperature heating controller 13 starts Slowly warm the water in the w...

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PUM

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Abstract

The invention discloses a multispectral optical technology fused temperature measuring device. The temperature measuring device comprises a multispectral tunable laser device, a variable color filter,a light beam shaping device, a light beam bidirectional beam splitter, a reference arm, a spectrograph, a collimation and beam expanding lens assembly, a pinhole diaphragm, a high-velocity scanning galvanometer, a large-aperture microobjective, a water channel, an ultrasonic detector, a high-precision temperature heating controller, a temperature sensor and a computing unit. According to the device, internal temperature distribution condition of tissues for tumor local thermotherapy can be measured comprehensively and quickly in real time, imaging and accurate measurement can be carried out simultaneously on changed feature information of internal fine morphological structures of the tissues in the heating process, and rapid multi-dimensional imaging is provided in the state that the internal structures and components inside the tissues are changed in tumor thermotherapy.

Description

technical field [0001] The invention relates to a technology in the field of optical temperature measurement, in particular to a temperature measurement device integrated with multi-spectral and multi-optical technologies. Background technique [0002] Hyperthermia targeting the tumor site is one of the important means to inhibit tumor growth. Its basic principle is to use an external physical heat source to heat the target to increase the temperature of the tumor area, so as to achieve apoptosis of tumor cells without causing damage to normal tissues. therapeutic purposes. However, accurate and highly sensitive detection of the temperature change inside the target tissue during the temperature rising process is critical to improve the therapeutic effect. Traditional nuclear magnetic resonance detection technology can obtain high-resolution and high-contrast temperature rise images, but it takes a long time and is expensive, and this method is easily affected by tissue elec...

Claims

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Application Information

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IPC IPC(8): G01N21/31G01N21/17G01K11/00A61B5/01
CPCA61B5/015G01K11/00G01N21/1702G01N21/314G01N2021/1706G01N2021/3148
Inventor 赵庆亮刘刚陈小元
Owner XIAMEN UNIV
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