Nursing-type hand-washing disinfectant preparation

A technology of disinfectant and preparation, which is applied in the direction of antiviral agent, local antibacterial agent, emulsion delivery, etc. It can solve the problems of allergic reaction, strong irritating smell, and large irritation, so as to expand the scope of sterilization and protect the skin hand, the effect of improving the sterilization effect

Inactive Publication Date: 2018-02-09
山东天辰生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are two types of skin and hand disinfectants commonly used at home and abroad: one is ethanol, iodine, tincture of iodine and other disinfectants. Humans have allergic reactions after use, and are not suitable for long-term use on skin and hands; the other is a compound disinfectant of chlorhexidine acetate and ethanol, but the concentration of ethanol is as high as 50%-70%, so it has a strong pungent smell , and after use, the skin and hands will be dry and produce rashes, etc. The protective effect on the skin needs to be improved

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A kind of nursing type hand sanitizer preparation, calculated by weight percentage, comprises the following components:

[0022] Chlorhexidine acetate 0.3%, Benzalkonium bromide 0.1%, Triclosan 0.2%, Polyethylene glycol 0.1%, Methylated soybean oil 3.2%, Poloxamer 20%, Ethanol 20%, Ethanol 1.2% diamine tetraacetic acid and 6% nonylphenol polyoxyethylene ether, the rest is distilled water, and ethylenediamine tetraacetic acid adjusts the pH of the preparation to 6.2.

[0023] Preparation:

[0024] 1) After heating and stirring the formulated amount of chlorhexidine acetate, benzalkonium bromide, triclosan and methylated soybean oil, adding nonylphenol polyoxyethylene ether, stirring quickly and uniformly to obtain an oil phase; Add the polyethylene glycol and ethanol of the formulated amount to the distilled water of the formulated amount, and heat to the same temperature as the oil phase to obtain the aqueous phase;

[0025] 2) Under the condition of constant temperat...

Embodiment 2

[0027] A kind of nursing type hand sanitizer preparation, calculated by weight percentage, comprises the following components:

[0028] Chlorhexidine Acetate 0.4%, Benzalkonium Bromide 0.2%, Triclosan 0.1%, Polyethylene Glycol 0.08%, Hydrogenated Castor Oil 5%, Macrogol Lauryl Hydroxystearate 24%, 26% ethanol, 1.5% citric acid and 4% coconut oil amide, the balance is distilled water, and the pH regulator adjusts the pH of the preparation to 6.5.

[0029] Preparation:

[0030] 1) After heating and stirring the chlorhexidine acetate, benzalkonium bromide, triclosan and hydrogenated castor oil in the prescribed amount, add polyethylene glycol lauryl hydroxystearate, and stir quickly to obtain oil phase; add the polyethylene glycol and ethanol of formula quantity to the distilled water of formula quantity, be heated to the same temperature as oil phase, obtain water phase;

[0031] 2) Under the condition of constant temperature magnetic stirring, mix the water phase and the oil ...

Embodiment 3

[0033] A kind of nursing type hand sanitizer preparation, calculated by weight percentage, comprises the following components:

[0034] Chlorhexidine Acetate 0.5%, Benzalkonium Bromide 0.15%, Triclosan 0.3%, Polyethylene Glycol 0.12%, Methylated Soybean Oil 6%, Poloxamer 30%, Ethanol 30%, Lemon 1.0% trisodium citrate and 2% sodium dodecylbenzenesulfonate, the balance is distilled water, and the pH of the preparation is adjusted to 7 by trisodium citrate.

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PUM

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Abstract

The invention provides a nursing-type hand-washing disinfectant preparation. The nursing-type hand-washing disinfectant preparation is prepared from, by weight, 0.3-0.5% of chlorhexidine acetate, 0.1-0.2% of benzalkonium bromide, 0.1-0.3% of trichloro hydroxydiphenyl diethyl ether, 0.05-0.12% of polyethylene glycol, 0.2-6% of oil for injection, 6-30% of emulgator, 10-30% of ethyl alcohol, 0.05-2.0% of pH regulator, 1-10% of surface active agent and the balance distilled water, wherein the pH of the pH regulator is 6-7. The preparation can effectively play the killing effect on staphylococcus aureus, escherichia coli, candida sporogenes and human immunodeficiency virus, meets the strict disinfecting requirement and has no irritation to the skin.

Description

technical field [0001] The invention belongs to the technical field of disinfectant, in particular to a nursing type hand sanitizer preparation. Background technique [0002] Bacteria, viruses, parasite eggs and some harmful substances can spread through hands as an intermediary. Washing hands is an important measure to prevent infection. Keeping hands hygienic is considered a part of hand disinfection. In modern society, people have more opportunities for public communication, and the chances of infecting germs through hands are also increasing, especially for medical workers, in the work of diagnosis and treatment, nursing, physical examination and dressing changes of patients, direct and indirect germs caused by hands Infection tops the list. Therefore, good hand washing is an important means to ensure good health, and it is also the most effective way to control the spread of diseases and prevent infection. [0003] At present, there are two types of skin and hand disi...

Claims

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Application Information

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IPC IPC(8): A61K31/155A61K31/14A61K31/075A61K9/107A61K47/10A61P31/02A61P31/04A61P31/18
CPCA61K9/1075A61K31/075A61K31/14A61K31/155A61K47/10A61K2300/00Y02A50/30
Inventor 徐世达
Owner 山东天辰生物技术有限公司
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