Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Flow cytometry instrument based on micro-fluidic technology and linear array detector

A technology of linear array detector and microfluidic technology, applied in the field of flow cytometry, can solve the problem of low resolution of cell images, achieve good collection effect, high line frequency, and improve accuracy

Active Publication Date: 2017-12-22
XIAN UNIV OF TECH
View PDF5 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a flow cytometer based on microfluidic technology and linear array detectors, which solves the problem of extremely low resolution of cell images collected by existing flow cytometers

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Flow cytometry instrument based on micro-fluidic technology and linear array detector
  • Flow cytometry instrument based on micro-fluidic technology and linear array detector
  • Flow cytometry instrument based on micro-fluidic technology and linear array detector

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0029] The present invention will be described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0030] The present invention is based on the flow cytometer of microfluidic technology and linear array detector, such as figure 1 As shown, it includes a microfluidic chip 1 connected in sequence, a linear array detector 2 and a data processing device 3; wherein, the data processing device 3 has two structures: the first structure, such as figure 2 As shown, the data processing device 3 is a host computer PC14 provided with a data interface; the second structure, such as image 3 As shown, the data processing device 3 includes a data transmission module 4 and a data processing module 13 connected together.

[0031] Data processing module 13 has three kinds of structures, respectively as follows:

[0032] The first structure, such as Figure 4 As shown, the ASIC chip 15 is set in the data processing module 13;

[0033] The second structu...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a flow cytometry instrument based on a micro-fluidic technology and a linear array detector. The instrument includes, in a successively connected manner, a micro-fluidic chip, a linear array detector and a data processing apparatus, and includes a light source which is located right above the micro-fluidic chip. A linear main channel is formed inside the micro-fluidic chip, wherein one end of the main channel is provided with a sample inlet while the other end is provided with a sample outlet. The lower surface of the micro-fluidic chip is adhered to the upper surface of the linear array detector. An included angle theta is formed between the main channel and the linear array detector, 0 degree <= theta <= 90 degrees. The flow cytometry instrument mainly combines the cell movement in multiple micro-fluidic channels in the micro-fluidic chip and scanning imaging of a traditional linear array detector, so that compared with a flow cytometry instrument based on an area array detector and the micro-fluidic technology, the flow cytometry instrument can form a cell image in higher resolution ratio, and is more accurate and has higher speed in cell flowing counting.

Description

technical field [0001] The invention belongs to the technical field of cell detection devices, and relates to a flow cytometer based on microfluidic technology and linear array detectors. Background technique [0002] Cell detection plays an important role in medical research and detection of many diseases. However, the existing medical detection systems all have defects such as bulky, complicated detection process and long period. Microfluidic technology can integrate basic operations such as sample preparation, separation, reaction and detection in the chemical and biological fields on a chip of a few square centimeters. This kind of microfluidic chip is small, easy to use, and has the characteristics of micro-quantization of detection samples, fast analysis speed, low power consumption and automation, which makes it show a unique development prospect in the application of medical research. [0003] The combination of microfluidic technology into the cell detection syste...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G01N15/14
CPCG01N15/1434
Inventor 余宁梅方元王伍娟路伟刘仪
Owner XIAN UNIV OF TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com