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Emulsifiable paste for relieving itching and preparation method thereof

A technology of cream and cork, which is applied in ointment delivery, pharmaceutical formula, emulsion delivery, etc., and can solve the problems of high cost

Inactive Publication Date: 2017-12-15
NANJING HOSPITAL OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, apart from the high cost of some therapies, the compliance of its treatment of AD in children is also a difficult problem

Method used

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  • Emulsifiable paste for relieving itching and preparation method thereof
  • Emulsifiable paste for relieving itching and preparation method thereof
  • Emulsifiable paste for relieving itching and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0178] prescription

[0179]

[0180] Extraction process

[0181] Take Phellodendron Phellodendron, Radix Paeoniae Rubra, Atractylodes Rhizoma Atractylodes Rhizome, Radix Glycyrrhizae, Radix Paeoniae Alba, Comfrey, Sophora Sophorae, Vitex Bark, Kochia, Schizonepeta, Fangfeng, add 6 times the amount of water, decoct 3 times, 40 minutes each time, and combine the decoction , filter, concentrate, and let cool. Add alum, let it stand for 24h, take the supernatant, and set aside.

[0182] Cream Composition

[0183] Oil phase: 60g glyceryl monostearate, 15g stearic acid, 15g lanolin, 30g liquid paraffin, 0.3g ethylparaben

[0184] Water phase: glycerin 15g, sodium lauryl sulfate 1.5g, azone 6g, extract 154.2g

[0185] Cream preparation process

[0186] Weigh glyceryl monostearate, stearic acid, lanolin, liquid paraffin, ethylparaben, heat to 85°C, stir well, and use it as the oil phase for later use; take glycerin, sodium lauryl sulfate, nitrogen The ketone and medicinal ma...

Embodiment 2

[0188] prescription

[0189]

[0190] Extraction process

[0191] Take Phellodendron Phellodendron, Radix Paeoniae Rubra, Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Atractylodes Atractylodes Atractylodes Atractylodes Nepetae, an amount of 4 times the total weight of medicinal materials, decoct 2 times, each 50min Combine the decoction, filter, concentrate, and let cool. Add alum, let it stand for 24h, take the supernatant, and set aside.

[0192] Cream Composition

[0193] Oil phase: 45g glyceryl monostearate, 25g stearic acid, 25g lanolin, 40g liquid paraffin, 0.5g ethylparaben

[0194] Water phase: glycerin 10g, so...

Embodiment 3

[0198] prescription

[0199]

[0200] Extraction process

[0201] Take Phellodendron Phellodendron, Radix Paeoniae Rubra, Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Atractylodes Rhizoma Atractylodes Atractylodes Rhizoma Atractylodes Atractylodes Atractylodes Atractylodes Atractylodes Nepetae, an amount of 8 times the total weight of medicinal materials, decoct 3 times, each time 30min Combine the decoction, filter, concentrate, and let cool. Add alum, let it stand for 24h, take the supernatant, and set aside.

[0202] Cream Composition

[0203] Oil phase: 75g glyceryl monostearate, 10g stearic acid, 10g lanolin, 20g liquid paraffin, 0.2g ethylparaben ...

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Abstract

The invention discloses emulsifiable paste for relieving itching and a preparation method thereof. The emulsifiable paste comprises phellodendron barks, red peony roots, xanthium herbs, Rumex japonicus, stemona roots, arnebia roots, flavescent sophora roots, alum, golden larch bards, kochia fruits, schizonepeta, and radix saposhnikoviae; water extraction is used in order to obtain an extract; extract, glycerin, sodium dodecyl sulfate and azone are used as a water phase together, monoglyceride stearate, stearic acid, lanolin, liquid paraffin, and ethyl p-hydrobenzoate are used as an oil phase, and mixing and stirring are carried out in order to prepare emulsifiable paste. The emulsifiable paste has curative effects for simultaneous treatment of principal and subordinate symptoms with safety and low side effects, and a transparent film can be formed by coating on the skin with good adhesiveness and without air tightness and greasy feeling; and the product is easy to wash and remove.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to an antipruritic cream. Background technique [0002] Atopic dermatitis (Atopic Dermatitis, AD), also known as atopic eczema (Atopic Eczema), Besnier constitutional prurigo (Besnier, sprurigo diathesique) or genetic allergic eczema (Hereditary Eczema), is a disease that begins in infancy , skin disease that occurs frequently in children and adolescents, with skin itching, rash, desquamation, hypertrophy, etc. as the main clinical manifestations. Members are physically and mentally exhausted, which affects their normal work and life; in addition, the course of the disease is repeated and protracted, often causing skin erosions and scabs, lichenoid lesions, which seriously damage the skin health and appearance of children; and long-term sleep disorders also seriously affect children's growth and development. [0003] At present, there are many kin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61K9/06A61P17/00A61P17/04A61K33/06
CPCA61K9/0014A61K9/06A61K33/06A61K36/15A61K36/185A61K36/238A61K36/284A61K36/30A61K36/489A61K36/538A61K36/65A61K36/70A61K36/71A61K36/756A61K36/904A61K47/44A61K2236/331A61K2236/39A61K2300/00
Inventor 周芙琼隆红艳夏崇才张亚杰阮杰朱维娜
Owner NANJING HOSPITAL OF T C M
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