Devices, systems, and methods for the detection of analytes

A technology for analytes and target analytes, which is applied in the analysis of materials, biological materials, and materials analysis by electromagnetic means, and can solve the problems of long incubation time and time-consuming

Inactive Publication Date: 2017-11-28
PROTEOSENSE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, existing diagnostic methods (PCR, ELISA) are time consuming (>48 hours to result) and require long incubation times (>12 hours)

Method used

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  • Devices, systems, and methods for the detection of analytes
  • Devices, systems, and methods for the detection of analytes
  • Devices, systems, and methods for the detection of analytes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0105] Example 1: Handheld sensor for detection and quantification of Salmonella

[0106] Salmonella bacteria are a major public health problem. Salmonella enterica is estimated to cause approximately 1 million infections per year in the United States alone. Salmonella is mainly transmitted through contaminated food sources. Accurate detection of Salmonella spp. during harvest, food processing, manufacturing, and transportation is critical to preventing the spread of Salmonella spp. However, existing diagnostic methods (PCR, ELISA) are time consuming (>48 hours to result) and require long incubation times (>12 hours). Improved rapid devices, systems and methods for detecting and quantifying analytes such as Salmonella offer the potential to reduce the spread of foodborne illness.

[0107] Presentation of the Proposed Handheld ProteoSense Enteric Salmonella Detector

[0108] The ProteoSense Salmonella enterica detector is a device that rapidly detects analytes based on thei...

Embodiment 2

[0144] Example 2: Process Control Sensors for Detection and Quantification of Listeria

[0145] Listeria bacterium is a major public health concern. Many species of Listeria have been identified, several of which can cause disease in humans. The most problematic species is Listeria monocytogenes, which causes many infections per year in the US alone. Although the infection rate caused by Listeria is lower than that caused by Salmonella, the mortality rate of listeriosis (ie, infection caused by Listeria) is close to 50%, and the average medical cost exceeds $1M per case. Listeria is endemic in the environment, where it thrives in the cool, moist conditions commonly found in food processing plants. Listeria spp. are occurring with increasing frequency in a wide range of raw and processed foods. Accurate detection of Listeria spp. during harvest, processing, manufacturing, and transportation is critical to preventing its spread. A common source of Listeria contamination is t...

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Abstract

Disclosed are devices, systems, and methods for the rapid and accurate detection of analytes, including Salmonella.

Description

technical field [0001] The present application relates generally to devices, systems and methods for quantifying analytes. Background technique [0002] Rapid detection of analytes is important in a variety of situations. For example, foodborne pathogens such as Salmonella bacteria represent a major public health problem. Salmonella enterica is estimated to cause approximately 1 million infections per year in the United States alone. Salmonella is mainly transmitted through contaminated food sources. Accurate detection of Salmonella spp. during harvest, food processing, manufacturing, and transportation is critical to preventing the spread of Salmonella spp. However, existing diagnostic methods (PCR, ELISA) are time consuming (>48 hours to result) and require long incubation times (>12 hours). [0003] Improved rapid devices, systems and methods for detecting and quantifying analytes such as Salmonella offer the potential to reduce the spread of foodborne illness. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/26G01N33/50G01N27/414
CPCG01N33/5438G01N33/56911G01N27/4145Y02A50/30G01N2333/195H01L29/2003H01L29/205
Inventor 马克·T·伯恩埃兰迪·K·德·席尔瓦杰里迈亚·施莱
Owner PROTEOSENSE
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