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American cockroach extract-containing anti-inflammatory and antiulcer toothpaste

A technology of Periplaneta americana and extracts, applied in dentistry, digestive system, drug combination and other directions, can solve the problem of bacterial resistance and other problems, and achieve the effect of promoting tissue repair

Inactive Publication Date: 2017-11-21
李映波 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinically, Western medicine is mainly used to treat oral inflammation. Although this method has a quick effect, it will cause bacteria to develop drug resistance.

Method used

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  • American cockroach extract-containing anti-inflammatory and antiulcer toothpaste
  • American cockroach extract-containing anti-inflammatory and antiulcer toothpaste
  • American cockroach extract-containing anti-inflammatory and antiulcer toothpaste

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Prepare materials according to the following mass ratios:

[0045]Hydrated Silica 45.0%, Glycerin 12.0%, Macrogol 400 12.0%, Sodium Carboxymethyl Cellulose 1.0%, PVM / MA Copolymer 1.0%, Aspartame 0.1%, Sodium Lauryl Sulfate 1.5%, Sodium Lauroyl Sarcosinate 1.5%, Fragrance 0.3%, Methylparaben 0.01%, Butylparaben 0.01%, Triclosan 0.2%, Tranexamic Acid 0.05%, Wild Chrysanthemum Extract Extract 0.5%, Periplaneta americana extract 2.5%, deionized water balance.

[0046] Go through the following steps:

[0047] 1). Mix the above prepared sodium carboxymethylcellulose, PVM / MA copolymer, glycerin and polyethylene glycol 400 homogeneously, then add deionized water and mix well, heat to 80°C and keep for 18min , make sodium carboxymethyl cellulose, PVM / MA copolymer fully expand, then cool to room temperature, obtain mixed solution;

[0048] 2). Add aspartame, tranexamic acid, methyl p-hydroxybenzoate, butyl p-hydroxybenzoate, wild chrysanthemum extract, sodium lauryl sulfate, ...

Embodiment 2

[0052] Prepare materials according to the following mass ratios:

[0053] Hydrated Silica 51.0%, Glycerin 14.0%, Macrogol 400 14.0%, Sodium Carboxymethyl Cellulose 0.6%, PVM / MA Copolymer 0.6%, Aspartame 0.1%, Sodium Lauryl Sulfate 1.0%, Sodium lauroyl sarcosinate 1.0%, methyl p-hydroxybenzoate 0.01%, butyl p-hydroxybenzoate 0.01%, fragrance 0.3%, triclosan 0.2%, tranexamic acid 0.05%, wild chrysanthemum extract Extract 0.5%, Periplaneta americana extract 3.0%, deionized water balance.

[0054] Go through the following steps:

[0055] 1). Mix the above prepared sodium carboxymethylcellulose, PVM / MA copolymer, glycerin and polyethylene glycol 400 homogeneously, then add deionized water and mix well, heat to 85°C and keep for 15min , make sodium carboxymethyl cellulose, PVM / MA copolymer fully expand, then cool to room temperature, obtain mixed solution;

[0056] 2). Add aspartame, tranexamic acid, methyl p-hydroxybenzoate, butyl p-hydroxybenzoate, wild chrysanthemum extract, s...

Embodiment 3

[0060] Prepare materials according to the following mass ratios:

[0061] Hydrated Silica 50.0%, Glycerin 16.0%, Macrogol 400 16.0%, Sodium Carboxymethyl Cellulose 0.7%, PVM / MA Copolymer 0.7%, Aspartame 0.1%, Sodium Lauryl Sulfate 1.25%, Sodium lauroyl sarcosinate 1.25%, methyl p-hydroxybenzoate 0.01%, butyl p-hydroxybenzoate 0.01%, essence 0.3%; triclosan hydroxydiphenyl ether 0.2%, tranexamic acid 0.05%, wild chrysanthemum extract Extract 0.5%, Periplaneta americana extract 3.5%, deionized water balance.

[0062] Go through the following steps:

[0063] 1). Mix the above prepared sodium carboxymethylcellulose, PVM / MA copolymer, glycerin and polyethylene glycol 400 homogeneously, then add deionized water and mix well, heat to 90°C and keep for 10min , make sodium carboxymethyl cellulose, PVM / MA copolymer fully expand, then cool to room temperature, obtain mixed solution;

[0064] 2). Add aspartame, tranexamic acid, methyl p-hydroxybenzoate, butyl p-hydroxybenzoate, wild ch...

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Abstract

The invention provides an American cockroach extract-containing anti-inflammatory and antiulcer toothpaste. The toothpaste is produced from, by mass, 42.0-53.0% of hydrated silica, 20.0-38.0% of an excipient, 1.0-2.0% of glue, 0-1.5% of aspartame, 2.0-4.0% of a foaming agent, 0-0.3% of an essence, 0.02% of an antiseptic, 0-0.2% of trichlorohydroxydiphenyl ether, 0-0.05% of tranexamic acid, 0.5-6.0% of American cockroach extract, 0.1-1.5% of wild chrysanthemum flower extract, and the balance of deionized water, and the sum of mass fractions of all above components is 100%. The American cockroach extract is added to make the toothpaste have very good inflammation prevention, bacterium prevention and tissue repairing promotion effects, and the wild chrysanthemum flower extract which is also added in the invention has heat clearing, internal heat repelling, bacterial preventing, inflammation preventing, oxidation preventing and mutation preventing effects.

Description

technical field [0001] The invention relates to a toothpaste, in particular to an anti-inflammatory and anti-ulcer toothpaste containing an extract of Periplaneta americana and a production process thereof, belonging to the technical field of oral cleaning care products. Background technique [0002] Oral inflammation is a common disease, such as periodontitis, gingivitis, periodontal abscess, maxillofacial space infection, etc. Although it is not fatal, the physical pain and psychological impact on people cannot be tolerated. ignore. A large number of studies have shown that periodontal disease is caused by bacterial infection, and controlling plaque is the key to preventing oral inflammation. Clinically, Western medicine is mainly used to treat oral inflammation. Although this method has quick results, it will cause bacteria to develop drug resistance. The use of traditional Chinese medicine ingredients can prevent bacteria from developing drug resistance and achieve the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/98A61K8/9789A61Q11/00A61Q17/00A61P1/02
CPCA61K8/987A61K8/97A61Q11/00A61Q17/005
Inventor 李映波黎静孙笠雯赵思聪
Owner 李映波
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