Placental hydrolytic ultrafiltrate and preparation method and application thereof and female care gel

A technology for female care and ultrafiltrate, applied in skin care preparations, sexual diseases, fluid delivery, etc., can solve problems such as disrupting endocrine function, and achieve the effect of restoring ovarian cell vitality, delaying decline, and youthful body and mind.

Inactive Publication Date: 2017-09-29
佛山市南海区普罗圣塔生物科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In view of this, the present invention provides a placental hydrolysis ultrafiltrate and its preparation method, application and feminine care gel, aiming to solve the potential harm of interfering with the normal endocrine function of the human body through oral or injection of various sex hormone preparations in the prior art

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  • Placental hydrolytic ultrafiltrate and preparation method and application thereof and female care gel
  • Placental hydrolytic ultrafiltrate and preparation method and application thereof and female care gel
  • Placental hydrolytic ultrafiltrate and preparation method and application thereof and female care gel

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preparation example Construction

[0034] The invention provides a kind of preparation method of placenta hydrolysis ultrafiltrate, comprises the following steps:

[0035] Step 1. Weigh fresh or frozen placenta, remove fascia and large blood vessels in a clean and sterile environment, rinse it in sterile ice water at 4°C-10°C, and obtain the cleaned placenta;

[0036] Step 2, cutting the cleaned placenta obtained in step 1 into small pieces, and grinding it in a masher to obtain a crushed placenta;

[0037] Step 3. Add small molecular mass water with the same weight as the fresh or frozen placenta in step 1 to the pulverized placenta obtained in step 1, with a pH greater than 9.6, place it in a sterile stainless steel container, seal it, and store it at -20°C or below The temperature is quick-frozen overnight, and then placed in an environment of 4°C-10°C to completely thaw, and the quick-freezing and thawing operations are repeated several times to obtain the hydrolyzate;

[0038] Step 4, centrifuging the hyd...

Embodiment 1

[0044] Step 1. Weighing fresh human placenta, removing fascia and large blood vessels in a clean and sterile environment, rinsing it in sterile ice water at 4°C to obtain a cleaned placenta; wherein, the crushed placenta has a particle size of 60 mesh;

[0045] Step 2, cutting the cleaned placenta obtained in step 1 into small pieces, and grinding it in a masher to obtain a crushed placenta;

[0046] Step 3. Add small molecular mass water with the same weight as the fresh placenta in step 1 to the pulverized placenta obtained in step 2, with a pH of 12.5, place it in a sterile stainless steel container, seal it, and freeze it at -20°C overnight. Then place it in an environment of 4°C to completely thaw, and repeat quick-freezing and thawing operations 3 times to obtain a hydrolyzate;

[0047] Wherein, the small molecular cluster water is composed of 3-6 water molecules, and its movement speed is fast, and it has extremely strong penetrating power, diffusing power and dissolvin...

Embodiment 2

[0051] Step 1. Weigh the frozen placenta of the animal, thaw it completely in an environment of 4°C in advance, remove the fascia and large blood vessels in a clean and sterile environment, and rinse it in sterile ice water at 10°C to obtain a cleaned placenta;

[0052] Step 2, cutting the cleaned placenta obtained in step 1 into small pieces, and crushing it in a masher to obtain a crushed placenta; wherein, the particle size of the crushed placenta is 120 mesh;

[0053] Step 3. Add small molecule water with a pH equal to the weight of the frozen placenta in step 1 to the pulverized placenta obtained in step 2, and place it in a sterile stainless steel container, seal it, and quickly freeze it overnight at a temperature of -25°C. Then put it in an environment of 7°C to completely thaw, and repeat quick freezing and thawing operations 4 times to obtain a hydrolyzate;

[0054] Step 4, centrifuging the hydrolyzate obtained in step 3 in a centrifuge for 45 minutes to obtain a sup...

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Abstract

The present invention provides a placental hydrolytic ultrafiltrate and a preparation method and application thereof and a female care gel. The female care gel is prepared from the placental hydrolytic ultrafiltrate as a main raw material, the placental hydrolytic ultrafiltrate is prepared by a special process, the molecular weight is 1KD to 10KD, the placental hydrolytic ultrafiltrate can be used for effective removal of free hormone with the molecular weight of 1KD or below, and may not lead to rebound caused by drug withdrawal ceasing, the placental hydrolytic ultrafiltrate is rich in a variety of small molecule effective components such as growth stimulating and regulating factors, through local medication to women's reproductive tract, the placental hydrolytic ultrafiltrate is absorbed into blood by mucous membranes and fast reaches the ovary, and has a special effect to restore ovarian cell viability and stimulate ovarian cell regeneration; in addition, the placental hydrolytic ultrafiltrate can significantly enhance various functions of the ovary, slows the decline of the functions of the ovary, corrects the endocrine function disorder of the female, and makes the female in a healthier and younger physical and mental state.

Description

technical field [0001] The invention relates to the field of biotechnology, and in particular to a placenta hydrolysis ultrafiltrate, its preparation method, application and female care gel. Background technique [0002] As adult women grow older, ovarian function usually begins to decline gradually from the age of 28, accompanied by the gradual aging of skin appearance and mentality. Oral and injection of various sex hormone preparations can replace declining ovarian function, but its suppression of ovarian function leads to serious "drug withdrawal rebound", which has been completely banned at present. In addition, oral administration of some natural extracts similar to sex hormone molecules such as phytosterols has a certain effect on delaying the decline of ovarian function, but due to the differences in the molecular structure of phytosterols and the destruction of active ingredients by the digestive system during oral administration, the effect is very serious. limite...

Claims

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Application Information

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IPC IPC(8): A61K35/50A61K9/06A61K8/04A61K8/98A61Q19/00A61P15/00A61P15/08
Inventor 蔡豪斌
Owner 佛山市南海区普罗圣塔生物科技有限公司
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