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liquid oral composition

A composition and oral technology, which can be used in oral care, cosmetic preparations, dentistry, etc., can solve problems such as difficulty in fully exerting the sterilization effect of IPMP

Active Publication Date: 2020-10-27
LION CORP
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  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

) is a nonionic bactericide with a high penetrating bactericidal effect. It is known that it is effective for the prevention or suppression of periodontal disease, but it is difficult to fully exert the bactericidal effect of IPMP in a liquid oral composition

Method used

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Embodiment Construction

[0027] The present invention is further described in detail below. The liquid oral composition of the present invention contains (A) isopropylmethylphenol, (B) cetylpyridinium chloride, (C) N-acyl taurate, and (D) a nonionic surfactant.

[0028] (A) Isopropylmethylphenol is a nonionic bactericide that imparts an osmotic bactericidal effect on periodontal pathogenic biofilms, and its addition amount is preferably 0.01 to 0.1% (mass%, the same below) of the total composition. ), more preferably 0.02 to 0.08%. The more the amount added, the higher the osmotic bactericidal effect on periodontal pathogenic biofilm, and when it is more than 0.01%, sufficient osmotic bactericidal effect on periodontal pathogenic biofilm can be exhibited. When it is less than 0.1%, it is also suitable for preventing the generation of turbidity and preventing the expression of peculiar smell.

[0029] (B) The amount of cetylpyridinium chloride added is preferably 0.01 to 0.1% of the total composition...

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Abstract

To provide a liquid composition for oral cavity, which has excellent osmotic and bactericidal effects on periodontal pathogenic biofilms and bactericidal effects on planktonic bacteria, in addition, suppresses turbidity during high-temperature storage, has good appearance stability, and is effective for periodontal The prevention or inhibition of the disease is effective, and the liquid oral composition is prepared as follows: in the liquid oral composition containing (A) isopropylmethylphenol and (B) cetylpyridinium chloride, add 0.1 to 0.6% by mass (C) N-acyl taurate and 0.1-0.8 mass % (D) nonionic surfactant.

Description

technical field [0001] The present invention relates to a liquid oral composition containing isopropylmethylphenol, which is excellent in the osmotic sterilization effect on the periodontal pathogenic biofilm in the oral cavity and the bactericidal effect on planktonic bacteria, and can suppress turbidity during high-temperature storage , has good appearance stability, and is effective in preventing or inhibiting periodontal disease. Background technique [0002] Isopropylmethylphenol (hereinafter abbreviated as IPMP) as a nonionic bactericide is a nonionic bactericide with a high penetrating bactericidal effect on periodontal pathogenic biofilm (hereinafter abbreviated as BF), and it is known It is effective for the prevention or suppression of periodontal disease, but it is difficult to fully exert the bactericidal effect of IPMP in a liquid oral composition. [0003] Therefore, in order to ensure the solubilization of IPMP in the liquid oral composition and the osmotic b...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/34A61K8/46A61K8/49A61K8/86A61Q11/00
CPCA61K8/34A61K8/46A61K8/49A61Q11/00A61K8/86A61K8/347
Inventor 加藤妥治泷沙织
Owner LION CORP
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