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Decoction piece prepared from superfine Chinese medicinal powder and preparation method thereof

A technology of traditional Chinese medicinal materials and ultra-fine powder, which is applied in the directions of pharmaceutical formula, powder transportation, plant raw materials, etc., and can solve the problems of the release rate of active ingredients, etc., to shorten the time of fine grinding, reduce the possibility of moisture absorption, and reduce hardness Effect

Active Publication Date: 2017-09-22
达嘉维康生物制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the preparation process of the prior art, in order to prevent the problem of "caking" in the prepared Chinese herbal medicine pieces, it is usually necessary to add water or ethanol to granulate the Chinese herbal medicine after being pulverized to obtain the granulated Chinese herbal medicine pieces, and the granulated Chinese herbal medicine Decoction pieces have a certain impact on the release rate of active ingredients in Chinese herbal medicines

Method used

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  • Decoction piece prepared from superfine Chinese medicinal powder and preparation method thereof

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preparation example Construction

[0030] figure 1 It is a flowchart of a preparation method of Chinese herbal medicine fine powder decoction pieces shown in the embodiment of the present application; the preparation method includes:

[0031] S101 dry-cleaning the dried Chinese herbal medicines, mechanically crushing them to 10-20 meshes, and obtaining coarse powder of pure medicinal materials;

[0032] The coarse powder of pure medicinal materials can be directly used as traditional Chinese medicinal materials in clinical practice of traditional Chinese medicine.

[0033] The coarse powder of the pure medicinal material is embrittled at low temperature to obtain the embrittled Chinese medicinal material; the attention is paid to the Chinese medicinal material;

[0034] In the coarse crushing process, the coarse crushing adopts the shearing method to achieve the effect of crushing Chinese herbal medicines. The cost of the crushing process is low, and the processing capacity of Chinese medicinal materials is l...

Embodiment 1

[0082] The fresh angelica is placed in a microwave vacuum drier to dry until the water content is less than or equal to 3%, and the dried angelica is obtained.

[0083] Then the dried angelica is placed in a mechanical crushing device for mechanical crushing, and the motor drives the impeller to cut the angelica into coarse particles of 10-20 mesh.

[0084] At the same time, the angelica is separated from the angelica in the process of coarse crushing, but the soil at the joint between the angelica and the angelica is exposed on the surface of the angelica, and at this time, the soil is separated from the angelica under the blowing of compressed air.

[0085] The 10 mesh-20 mesh angelica coarse particles are subjected to embrittlement treatment, and the embrittlement temperature is kept at -40-50°C. After the embrittlement treatment, the toughness of angelica will change, the toughness of angelica will disappear, and angelica will become brittle or even vitrified.

[0086] The e...

Embodiment 2

[0093] The fresh rhubarb is dried in a microwave vacuum dryer until the water content is less than or equal to 3%, and the dried rhubarb is obtained.

[0094] Then the dried rhubarb is placed in a mechanical crushing device for mechanical crushing, and the motor drives the impeller to cut the rhubarb into 10-20 mesh rhubarb coarse particles.

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Abstract

The invention discloses a decoction piece prepared from superfine Chinese medicinal powder and a preparation method thereof. According to the preparation method, dried Chinese medicinal materials are coarsely ground first, and then coarse Chinese medicinal powder is embrittled to destroy the toughness of the clean coarse Chinese medicinal powder, shorten the fine grinding time and reduce the moisture absorption possibility of the Chinese medicinal materials so as to solve a caking problem of the prepared traditional Chinese medicinal decoction piece. By the preparation method, plant fiber in the traditional Chinese medicinal decoction piece is dissociated, so that the structure of the traditional Chinese medicinal decoction piece is loose, the hardness of the traditional Chinese medicinal decoction piece is reduced, subsequent fine grinding is facilitated, the fine grinding time is shortened, the moisture absorption possibility of the traditional Chinese medicinal decoction piece in the fine grinding process is reduced, and the caking problem of the prepared traditional Chinese medicinal decoction piece is avoided. By the preparation method disclosed by the embodiment of the invention, the fine grinding time is shortened, the moisture absorption possibility of the traditional Chinese medicinal decoction piece in the fine grinding process is reduced, the granulating process in the conventional preparation method is eliminated, and the release rate of active components of the prepared traditional Chinese medicinal decoction piece is high.

Description

technical field [0001] The invention relates to the technical field of Chinese medicinal materials, in particular to an ultrafine powder decoction piece of Chinese medicinal materials and a preparation method thereof. Background technique [0002] The active ingredients in Chinese herbal medicines are mainly distributed in the cells. For conventional decoction pieces, the Chinese herbal medicines are stored as fine powder. When eating, the active ingredients stored in the cells are released by decoction. During the decoction process, the active ingredients in the cells must pass through one or even dozens of cell walls to be released. Usually the active ingredients have a long onset time and low utilization rate. Superfine pulverization technology is a new technology developed in the past 20 years. The superfine pulverization technology can pulverize the material into extremely fine powder, so that the cell wall breaking rate of Chinese medicinal materials can reach more t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/00A61K9/14A61K36/232A61K36/708
CPCA61K9/14A61K36/00A61K36/232A61K36/708
Inventor 黄生武易志红
Owner 达嘉维康生物制药有限公司
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