Amino acid gold nanoparticle and preparation method and application thereof

Abstract

The embodiment of the invention discloses an amino acid gold nanoparticle and a preparation method and application thereof. The amino acid gold nanoparticle is synthesized by a gold nanoparticle and amino acid. The embodiment of the invention further discloses a corresponding preparation method and application of the amino acid gold nanoparticle. The amino acid gold nanoparticle is beneficial to achievement of detection of the concentration of heavy metal ions in a living body.

Description

technical field [0001] The invention relates to the technical field of nanomedicine, in particular to amino acid gold nanoparticles, a preparation method and application thereof. Background technique [0002] With the improvement of people's attention to health, the poisoning caused by heavy metal ions has attracted more and more attention. In daily life, heavy metal ions affect people's life and health all the time, and a very small amount of heavy metal ions (such as divalent mercury ions, dimethyl lead ions) can endanger human life. Among the poisoning caused by heavy metal ions, mercury, lead, and thallium poisoning are the most common types of heavy metal ion poisoning. Taking mercury ion as an example, mercury ion is one of the most threatening and toxic metal ions to the human body and the environment. It has varying degrees of toxic effects on the brain, bones, kidneys, central nervous system, immune and endocrine systems. And its pollutants can pollute a large amo...

AI Technical Summary

Problems solved by technology

However, the existing heavy metal detection methods lack specificity in clinical practice and the detection methods are very lagging behind. Over time, misdiagnosis, missed diagnosis and delayed diagnosis are common. research hotspots

[0003] Although there are many methods for the detection of heavy metal ions, such as atomic absorption, electron paramagnetic resonance, fluorescent probes, etc., these methods are not capable of intuitive and real-time detection of ions in vivo, and the pretreatment of samples is also relatively complicated. The interference of other cations cannot be ruled out, and the probe-based metal ion detection has defects such as low selectivity of the probe and poor water solubility of the probe, so the traditional method for detecting metal examples is limited in practice.

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