Preparation method of magnetic ordered mesoporous carbon nanospheres for magnetic targeted drug delivery

Abstract

The invention relates to a preparation method of magnetic ordered mesoporous carbon nanospheres for magnetic targeted drug delivery. Aiming at the defects of non-specificity and high toxicity of antitumor drugs, with phenol, formaldehyde, sodium hydroxide and alpha-type iron oxide as raw materials and iron nitrate as a magnetic agent, after hydrothermal synthesis and vacuum sintering at high temperature are conducted, the magnetic ordered mesoporous carbon nanospheres are prepared as a controlled release formulation of a cancer targeted drug. According to the preparation method, the process is advanced, and data is complete and accurate; the product is black powder particles, the particle size is <= 100 nm, the specific surface area of the nanospheres reaches 344.9 m<2> / g, the particles have magnetic ordered mesoporous structures with the pore diameter of the mesoporous <= 3 nm, and the purity of the product reaches 99.8%; the preparation method of the magnetic ordered mesoporous carbon nanospheres is advanced.

Description

technical field [0001] The invention relates to a method for preparing magnetically ordered mesoporous carbon nanospheres for magnetically targeted drug delivery, and belongs to the technical field of preparation and application of biomedical materials. Background technique [0002] Cancer is one of the diseases that seriously threaten human health. Chemotherapy has always played an important role in cancer treatment, but antitumor drugs have the disadvantages of non-specificity and high toxicity. In the process of killing tumor cells, they will also Normal tissues are damaged to varying degrees, resulting in a decline in the immune function of the human body, and drug treatment is also affected by drug dose dependence, resulting in poor cancer treatment effect. [0003] Magnetic targeted drug delivery preparation is a targeting preparation composed of magnetic nanoparticles, drug carriers and drug molecules. , pH stimulation, realize the slow release of the drug, the magne...

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Problems solved by technology

[0002] Cancer is one of the diseases that seriously threaten human health. Chemotherapy has always played an important role in cancer treatment, but antitumor drugs have the disadvantages of non-specificity and high toxicity. In the process of killing tumor cells, they will also Damage to normal tissues to varying degrees, resulting in a decline in the immune function of the human body, and drug treatment is also affected by drug dose dependence, resulting in poor cancer treatment effect

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