Preparation method of magnetic ordered mesoporous carbon nanospheres for magnetic targeted drug delivery

A technology of targeted drug delivery and mesoporous carbon, which is applied in the direction of nano-carbon, pharmaceutical formulations, medical preparations containing active ingredients, etc., and can solve the problem of damaged tissues, non-specificity of anti-tumor drugs, high toxicity, and decreased immune function of the human body, etc. question

Active Publication Date: 2017-08-11
TAIYUAN UNIV OF TECH
View PDF4 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Cancer is one of the diseases that seriously threaten human health. Chemotherapy has always played an important role in cancer treatment, but antitumor drugs have the disadvantages of non-specificity and high toxicity. In the process of killing tumor cells, they will also Damage to normal tissues to varying degrees, resulting in a decline in the immune function of the human body, and drug treatment is also affected by drug dose dependence, resulting in poor cancer treatment effect

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of magnetic ordered mesoporous carbon nanospheres for magnetic targeted drug delivery
  • Preparation method of magnetic ordered mesoporous carbon nanospheres for magnetic targeted drug delivery
  • Preparation method of magnetic ordered mesoporous carbon nanospheres for magnetic targeted drug delivery

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0101] The present invention will be further described below in conjunction with accompanying drawing:

[0102] figure 1 As shown, it is a state diagram of vacuum sintered magnetically ordered mesoporous carbon nanospheres. The position and connection relationship of each part must be correct, the installation should be firm, and the operations should be performed in sequence.

[0103] Quantities of the chemicals used in the preparation are determined in grams, milliliters, centimeters according to a pre-set range 3 is the unit of calculation.

[0104] The vacuum sintering furnace is vertical, the lower part of the vacuum sintering furnace 1 is the furnace seat 2, the upper part is the furnace cover 3, and the inside is the furnace chamber 4; Put quartz container 6, be provided with stainless steel wire mesh 7 on quartz container 6 tops, put magnetically ordered mesoporous carbon nanosphere 8 in quartz container 6 built-in; On the inner wall of vacuum sintering furnace 1, be...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a preparation method of magnetic ordered mesoporous carbon nanospheres for magnetic targeted drug delivery. Aiming at the defects of non-specificity and high toxicity of antitumor drugs, with phenol, formaldehyde, sodium hydroxide and alpha-type iron oxide as raw materials and iron nitrate as a magnetic agent, after hydrothermal synthesis and vacuum sintering at high temperature are conducted, the magnetic ordered mesoporous carbon nanospheres are prepared as a controlled release formulation of a cancer targeted drug. According to the preparation method, the process is advanced, and data is complete and accurate; the product is black powder particles, the particle size is <= 100 nm, the specific surface area of the nanospheres reaches 344.9 m<2> / g, the particles have magnetic ordered mesoporous structures with the pore diameter of the mesoporous <= 3 nm, and the purity of the product reaches 99.8%; the preparation method of the magnetic ordered mesoporous carbon nanospheres is advanced.

Description

technical field [0001] The invention relates to a method for preparing magnetically ordered mesoporous carbon nanospheres for magnetically targeted drug delivery, and belongs to the technical field of preparation and application of biomedical materials. Background technique [0002] Cancer is one of the diseases that seriously threaten human health. Chemotherapy has always played an important role in cancer treatment, but antitumor drugs have the disadvantages of non-specificity and high toxicity. In the process of killing tumor cells, they will also Normal tissues are damaged to varying degrees, resulting in a decline in the immune function of the human body, and drug treatment is also affected by drug dose dependence, resulting in poor cancer treatment effect. [0003] Magnetic targeted drug delivery preparation is a targeting preparation composed of magnetic nanoparticles, drug carriers and drug molecules. , pH stimulation, realize the slow release of the drug, the magne...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C01B32/15C01G49/08A61K41/00A61K47/02A61K9/14A61K31/704A61P35/00
CPCA61K9/0009A61K9/143A61K31/704A61K41/0052C01G49/08C01P2002/72C01P2002/84C01P2004/04C01P2004/32C01P2004/51C01P2004/64C01P2004/80C01P2006/12C01P2006/17C01P2006/80
Inventor 陈琳刘旭光杨永珍张欢
Owner TAIYUAN UNIV OF TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap