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Traditional Chinese medicine soft capsule for treating ankylosing spondylitis and preparation method thereof

A technology for ankylosing spondylitis and soft capsules, applied in capsule delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problem of single dosage form, achieve significant curative effect, improve drug stability, and reduce unit dosage Effect

Inactive Publication Date: 2017-07-14
AFFILIATED HOSPITAL OF ZUNYI MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the formulations of Chinese patent medicines for the treatment of ankylosing spondylitis are relatively single, mainly tablets and pills

Method used

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  • Traditional Chinese medicine soft capsule for treating ankylosing spondylitis and preparation method thereof
  • Traditional Chinese medicine soft capsule for treating ankylosing spondylitis and preparation method thereof
  • Traditional Chinese medicine soft capsule for treating ankylosing spondylitis and preparation method thereof

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Effect test

Embodiment 1

[0033] An embodiment of the traditional Chinese medicine soft capsule for treating ankylosing spondylitis of the present invention, the traditional Chinese medicine soft capsule described in this embodiment includes a capsule fluid and a capsule shell, and the capsule fluid is composed of a Chinese medicine extract and a pharmaceutical auxiliary material. The mass ratio of the Chinese medicine extract to the pharmaceutical excipient is 1:1.2, and the Chinese medicine extract is composed of the following components by weight: 25 parts of Clematis clematis extract, 40 parts of Ivy vine extract, 25 parts of Rhizoma Drynariae extract parts, 10 parts of Achyranthes bidentata extract; the pharmaceutical adjuvant consists of the following components by weight: 8 parts of diluent, 7 parts of suspending agent, 2 parts of antioxidant, wherein the diluent is vegetable oil, and the auxiliary The suspension is a mixture of 10% to 30% oil and wax, and the antioxidant is a food-grade antioxid...

Embodiment 2

[0045] An embodiment of the traditional Chinese medicine soft capsule for treating ankylosing spondylitis of the present invention, the traditional Chinese medicine soft capsule described in this embodiment includes a capsule fluid and a capsule shell, and the capsule fluid is composed of a Chinese medicine extract and a pharmaceutical auxiliary material. The mass ratio of the Chinese medicine extract to the pharmaceutical excipient is 1:1.4, and the Chinese medicine extract is composed of the following components by weight: 25 parts of Clematis clematis extract, 30 parts of Ivy vine extract, 35 parts of Rhizoma Drynariae extract part, 10 parts of Achyranthes bidentata extract; the pharmaceutical adjuvant consists of the following components by weight: 10 parts of diluent, 8 parts of suspending agent, 3 parts of antioxidant, wherein the diluent is vegetable oil, and the auxiliary The suspension is a mixture of 10% to 30% oil and wax, and the antioxidant is a food-grade antioxid...

Embodiment 3

[0048] An embodiment of the traditional Chinese medicine soft capsule for treating ankylosing spondylitis of the present invention, the traditional Chinese medicine soft capsule described in this embodiment includes a capsule fluid and a capsule shell, and the capsule fluid is composed of a Chinese medicine extract and a pharmaceutical auxiliary material. The mass ratio of the Chinese medicine extract to the pharmaceutical excipient is 1:1.5, and the Chinese medicine extract is composed of the following components by weight: 30 parts of Clematis clematis extract, 30 parts of Ivy vine extract, 30 parts of Rhizoma Rhizoma Rhizoma part, 10 parts of Radix Achyranthes Radix Extract; described pharmaceutical excipient is made up of the component of following parts by weight: diluent 11 parts, suspending agent 7 parts, antioxidant 4 parts, wherein said diluent is vegetable oil, and described auxiliary The suspension is a mixture of 10% to 30% oil and wax, and the antioxidant is a food...

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Abstract

The invention discloses a traditional Chinese medicine soft capsule for treating ankylosing spondylitis and a preparation method thereof. The traditional Chinese medicine soft capsule comprises a capsule solution and a capsule shell. The capsule solution is composed of a traditional Chinese medicine extract and medicinal auxiliary materials. The traditional Chinese medicine extract is composed of the following components in parts by weight: 20 to 40 parts of clematis root extract, 20 to 40 parts of sinomenium acutum extract, 20 to 40 parts of rhizoma drynariae extract, and 10 to 20 parts of achyranthes root extract. The provided traditional Chinese medicine soft capsule has the advantages of user-friendliness, rapid effect, high bioavailability, and high stability, the concentration of traditional Chinese medicine extract in the soft capsule is enough, and thus the soft capsule has the functions of clearing and activating the channels and collaterals, tonifying the kidney, and activating blood, and has a prominent curative effect on various kinds of ankylosing spondylitis.

Description

technical field [0001] The invention relates to a Chinese patent medicine and a preparation method thereof, in particular to a traditional Chinese medicine soft capsule for treating ankylosing spondylitis and a preparation method thereof. Background technique [0002] Ankylosing spondylitis (AS), also known as deforming spondylitis, atrophic spondylitis, bamboo spondylosis, etc., is a chronic progressive, independent, systemic disease of unknown etiology. AS belongs to the category of "big hunchback" and "stubborn numbness" in traditional Chinese medicine. It is a disease mainly characterized by chronic inflammation of the axial joints. The lesions mainly involve the sacroiliac joints, the small intervertebral joints of the spine, and the hips, knees, and ankles of the lower limbs. Joints and other large joints. In the early stage of clinical practice, back stiffness and pain are the main symptoms. Chronic progression and prolonged healing can cause spinal rigidity and fibr...

Claims

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Application Information

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IPC IPC(8): A61K36/716A61K36/72A61K9/48A61P19/08
CPCA61K9/4808A61K9/4858A61K36/12A61K36/126A61K36/21A61K36/264A61K36/59A61K36/716A61K36/72A61K2300/00
Inventor 王信
Owner AFFILIATED HOSPITAL OF ZUNYI MEDICAL COLLEGE
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