Self-emulsifying eicosapentaenoic acid nutrient composition and application thereof
A nutritional composition and self-emulsifying technology, applied in the directions of drug combinations, plant raw materials, medical preparations containing active ingredients, etc., can solve the problems of irritation, easy recurrence, inconvenience in eating, etc., and achieve increased absorption in the body, significant treatment effect, effect without dependency
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Embodiment 1
[0022] Recipe: (weight)
[0023]
[0024] Mix EPA and emulsifier, then add grape seed extract and vitamin K2, stir evenly, and fill soft capsules.
Embodiment 2
[0027] Recipe: (weight)
[0028]
[0029] Mix EPA and emulsifier, then add grape seed extract and vitamin K2, stir evenly, and fill hard capsules.
[0030] The EPA is from tuna oil.
Embodiment 3
[0032] 1. Animal experiments
[0033] (1) Animal selection: 40 weaned Wistar rats with a body weight of 80-100 g were selected. Rats were reared in single cages and randomly divided into 4 groups, 10 in each group. Animals were housed in separate cages and acclimatized for at least one week prior to experimentation. The animal laboratory was equipped with automatic temperature (22±1°C) and lighting control (12 hours light / 12 hours dark). The experimental procedures and animal feeding of animals were carried out in accordance with the institutional guidelines of the "Manual for the Care and Use of Laboratory Animals" of the National Institutes of Health.
[0034] (2) Drug administration: all adopt oral administration, and the dose is expressed as administration amount (g) / body weight (kg)
[0035] (3) Acute inflammation model: the anti-inflammatory effect of the composition was studied using the acute inflammation model induced by cross-vegetable gum.
[0036] Rats received...
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