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Probiotic composite composition containing bifidobacterium and lactobacillus acidophilus and application

A composite composition, the technology of Lactobacillus acidophilus, applied in the direction of bifidobacteria, medical preparations containing active ingredients, Lactobacillus, etc., can solve the problems of reduced number of viable bacteria and single composition, so as to reduce the side effects of antibiotics and acid resistance And strong bile resistance, the effect of improving constipation

Inactive Publication Date: 2017-06-20
家家乐购(北京)科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] In order to overcome the defect that the above-mentioned probiotic product has a single composition and the number of viable bacteria decreases with time, the present invention provides a probiotic composite composition containing Bifidobacterium Bb-12 and Lactobacillus acidophilus La-5, and In the preparation of nutritional products for improving constipation, bad breath and skin quality, the probiotic compound composition can also be used in combination with goat milk powder or antibiotics

Method used

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  • Probiotic composite composition containing bifidobacterium and lactobacillus acidophilus and application
  • Probiotic composite composition containing bifidobacterium and lactobacillus acidophilus and application
  • Probiotic composite composition containing bifidobacterium and lactobacillus acidophilus and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] The steps of making the probiotic complex composition into tablets include:

[0057] (1) Enlarge and cultivate Bb-12 and La-5 bacterial strains with conventional method fermentation;

[0058] (2) Take 1g of strain Bb-12 and 1g of strain La-5, add 1g of inulin, mix, add 15g of resistant dextrin, and mix;

[0059] (3) starch is passed through 80 mesh sieves, and is used as an auxiliary material in the preparation for subsequent use;

[0060] (4) Add the starch obtained in step (3) to the mixed powder obtained in step (2) until the weight is 100g;

[0061] (5) Use a one-step granulator to granulate the above-mentioned mixed powder, pass through a 10-mesh sieve, then add 0.4% magnesium stearate, use a conventional tablet press to compress tablets (the specification is 1g / tablet), and then coat (conventional film-coated), bottled.

Embodiment 2

[0063] This example uses the same method as in Example 1 to prepare tablets, except that the amount of each component is changed to 3g of strain Bb-12, 3g of strain La-5, 5g of inulin, 23g of resistant dextrin, and starch as the carrier. The tablet specification is 1g / tablet.

Embodiment 3

[0065] The present embodiment adopts the substantially same method as embodiment 1 to prepare capsules. The difference is that the dosage of each component becomes: 2g strain Bb-12, 2g strain La-5, 3g inulin, 18g resistant dextrin, and starch as carrier. Adopt a one-step granulator to granulate all the mixed powders, pass through a 10-mesh sieve, and then use a fully automatic capsule filling machine to pack the granulated granules into capsules to obtain capsules (the specification is 0.5g / capsule of content).

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Abstract

The invention provides a probiotic composite composition containing bifidobacterium and lactobacillus acidophilus and application of the probiotic composite composition. The probiotic composite composition is prepared from the following components in parts by weight: 0.2 to 0.8 part by weight of probiotics, 0.1 to 0.7 part by weight of inulin and 1.5 to 2.7 parts by weight of soluble dietary fiber. The probiotic composite composition provided by the invention is a composite intestinal health nutrient product; the number of viable bacteria is not attenuated along with time; a flora has good acid resistance and bile resistance; the probiotic composite composition has clinically-verified health efficacy; for a 28-unit type probiotic composite preparation, each unit contains the probiotic composite composition and a description; the probiotic composite composition is used for crowds with constipation, ozostomia and skin problem and crowds taking antibiotics; according to the probiotic composite composition, constipation and ozostomia symptoms of the crowds can be improved, the skin type is improved, side effects of the antibiotics are reduced, and the life quality of the crowds is improved.

Description

technical field [0001] The present invention relates to a probiotic composite composition containing bifidobacteria and Lactobacillus acidophilus and its application, in particular to a probiotic composition comprising Bifidobacterium B.bifidum-12 (Bb-12) and Lactobacillus acidophilus L.acidophilu-5 (La-5) composite composition. Background technique [0002] At present, the internationally accepted definition of probiotics is "probiotics refer to one or more live microorganisms that have beneficial effects on the host when consumed in sufficient quantities, are able to resist gastric acid and bile, and reach the intestinal tract alive, where they can Colonize for a certain period of time.” So far, the probiotics that scientists have discovered can be roughly divided into three categories, including lactobacilli, bifidobacteria and Gram-positive cocci. When the human body is full of probiotics, people will be in a healthy state, but once the balance of the flora in the body ...

Claims

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Application Information

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IPC IPC(8): A61K35/747A61P1/10A61P1/02A61P17/00A23L33/135A23L33/21A23L33/26A61K35/745A61K31/733
CPCA61K31/733A61K35/745A61K35/747A23V2002/00A23V2400/515A23V2400/113A61K2300/00A23V2200/32A23V2250/284A23V2250/5072A23V2250/5114A23V2250/51082
Inventor 唐挺
Owner 家家乐购(北京)科技有限公司
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