Predictive tumor system based on next generation sequencing

Abstract

A system for predicting tumors based on next-generation sequencing, including an anticoagulant blood collection tube for collecting blood, a DNA extraction kit, a next-generation sequencing device, and a gene mutation evaluation system. Extract whole blood DNA, the second generation sequencing device detects the sequence of the whole blood DNA, the gene mutation evaluation system analyzes the situation of gene mutation according to the sequence detected by the second generation sequencing device, and according to the tumorigenicity grade of the mutated gene And the dominant recessiveness of the gene predicts the risk level of tumor occurrence. The present invention adopts the second-generation sequencing platform second-generation sequencing device to sequence the gene, which is fast, so that the gene can be comprehensively sequenced, the tumor can be comprehensively screened, and the risk level of the tumor can be predicted through the gene mutation evaluation system, so that customers can do it as soon as possible. get ready. Analyze the situation of gene mutation, and predict the risk level of tumor occurrence according to the tumorigenicity level of the mutated gene and the dominant recessiveness of the gene, and fully consider the impact of the mutated gene on the occurrence of tumor, thus making the prediction more accurate.

Description

technical field [0001] The invention relates to the technical field of medical equipment, in particular to a next-generation sequencing-based tumor prediction system. Background technique [0002] Hereditary tumors are caused by mutations in specific disease-causing genes (such genes are called hereditary tumor-associated genes) and are clustered in families, accounting for about 5% to 10% of cancers, including gastric cancer, melanoma, Colorectal cancer, breast cancer, ovarian cancer, etc. [0003] The latest study in 2014 analyzed the spectrum of cancer epidemics in China, which showed that based on the average life expectancy of 74 years, the probability of each person suffering from malignant tumors in their lifetime is 22%. People with inherited tumor-associated gene mutations have an increased risk of malignancy. At present, most testing institutions can only provide several specific genetic tumor screenings, the screening range is not comprehensive, and the predicti...

AI Technical Summary

Problems solved by technology

At present, most testing institutions can only provide several specific genetic tumor screenings, the screening range is not comprehensive, and the prediction accuracy is relatively low

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